(Q38654054)

5 September 2017

title

Heart regeneration and repair after myocardial infarction: translational opportunities for novel therapeutics (English)

1 reference

5 September 2017

main subject

myocardial infarction

1 reference

Thomas J Cahill

1

1 reference

5 September 2017

Robin P Choudhury

series ordinal

2

1 reference

5 September 2017

Paul R Riley

series ordinal

3

1 reference

5 September 2017

publication date

21 July 2017

1 reference

Nature Reviews Drug Discovery

5 September 2017

published in

1 reference

https://scigraph.springernature.com/pub.10.1038/nrd.2017.106

5 September 2017

exact match

0 references

cites work

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The neprilysin pathway in heart failure: a review and guide on the use of sacubitril/valsartan

21 January 2018

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Current state of clinical translation of cardioprotective agents for acute myocardial infarction

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2017.106

Adult Stem Cell Therapy and Heart Failure, 2000 to 2016: A Systematic Review

21 January 2018

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Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration

21 January 2018

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Redirecting cardiac growth mechanisms for therapeutic regeneration

21 January 2018

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Evolution, comparative biology and ontogeny of vertebrate heart regeneration.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cryoinjury as a myocardial infarction model for the study of cardiac regeneration in the zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Hypoxia/reoxygenation cardiac injury and regeneration in zebrafish adult heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Heart regeneration in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Recapitulation of developmental cardiogenesis governs the morphological and functional regeneration of adult newt hearts following injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Extensive scar formation and regression during heart regeneration after cryoinjury in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Transient regenerative potential of the neonatal mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Functional Recovery of a Human Neonatal Heart After Severe Myocardial Infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Long-term myocardial scarring after operation for anomalous left coronary artery from the pulmonary artery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Some principles of regeneration in mammalian systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Mammalian heart renewal by pre-existing cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Adult c-kit(pos) cardiac stem cells are necessary and sufficient for functional cardiac regeneration and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

An emerging consensus on cardiac regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Bone marrow cells regenerate infarcted myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cardiac myocyte cell cycle control in development, disease, and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Evidence for cardiomyocyte renewal in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cardiomyocyte proliferation contributes to heart growth in young humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Meis1 regulates postnatal cardiomyocyte cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Requirement for neuregulin receptor erbB2 in neural and cardiac development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

GATA4 regulates Fgf16 to promote heart repair after injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The hippo pathway in heart development, regeneration, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Hippo pathway effector Yap promotes cardiac regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Chromatin regulation by Brg1 underlies heart muscle development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Clonally dominant cardiomyocytes direct heart morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Monitoring Tissue Regeneration at Single-Cell Resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cardiomyocyte cell cycle control and growth estimation in vivo--an analysis based on cardiomyocyte nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Six-Year Prognostic Value of Microvascular Obstruction After Reperfused ST-Elevation Myocardial Infarction as Assessed by Contrast-Enhanced Cardiovascular Magnetic Resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Coronary arteries form by developmental reprogramming of venous cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The epicardium signals the way towards heart regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Characterisation of the human embryonic and foetal epicardium during heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cellular origin and developmental program of coronary angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

C/EBP transcription factors mediate epicardial activation during heart development and injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Epicardial regeneration is guided by cardiac outflow tract and Hedgehog signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

De novo cardiomyocytes from within the activated adult heart after injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Extending the time window of mammalian heart regeneration by thymosin beta 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Arterial endothelial cells: still the craftsmen of regenerated endothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Genetic lineage tracing discloses arteriogenesis as the main mechanism for collateral growth in the mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Arteries are formed by vein-derived endothelial tip cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Insulin-Like Growth Factor 1 Receptor-Dependent Pathway Drives Epicardial Adipose Tissue Formation After Myocardial Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

tcf21+ epicardial cells adopt non-myocardial fates during zebrafish heart development and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Dynamic haematopoietic cell contribution to the developing and adult epicardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Regulation of the inflammatory response in cardiac repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Abandoning M1/M2 for a Network Model of Macrophage Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Alternatively activated macrophages determine repair of the infarcted adult murine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Foxp3+ CD4+ T cells improve healing after myocardial infarction by modulating monocyte/macrophage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Temporal neutrophil polarization following myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Acute inflammation initiates the regenerative response in the adult zebrafish brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Reparative inflammation takes charge of tissue regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Immune modulation of stem cells and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A special population of regulatory T cells potentiates muscle repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Macrophages commit postnatal endothelium-derived progenitors to angiogenesis and restrict endothelial to mesenchymal transition during muscle regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Macrophage Wnt7b is critical for kidney repair and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Acute inflammation stimulates a regenerative response in the neonatal mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Macrophages are required for neonatal heart regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Regeneration, tissue injury and the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Myocardial extracellular matrix: an ever-changing and diverse entity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Remodelling the extracellular matrix in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Normal newt limb regeneration requires matrix metalloproteinase function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A transitional extracellular matrix instructs cell behavior during muscle regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Scar-free wound healing and regeneration in amphibians: immunological influences on regenerative success

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cardiac morphology and blood pressure in the adult zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Reduced matrix rigidity promotes neonatal cardiomyocyte dedifferentiation, proliferation and clonal expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Human Ventricular Unloading Induces Cardiomyocyte Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Decellularized zebrafish cardiac extracellular matrix induces mammalian heart regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A dynamic spatiotemporal extracellular matrix facilitates epicardial-mediated vertebrate heart regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Periostin is essential for cardiac healing after acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Stimulating myocardial regeneration with periostin Peptide in large mammals improves function post-myocardial infarction but increases myocardial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Drug and cell delivery for cardiac regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Evolution of animal regeneration: re-emergence of a field

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

View from the heart: cardiac fibroblasts in development, scarring and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Transforming growth factor: beta signaling is essential for limb regeneration in axolotls

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Astrocyte scar formation aids central nervous system axon regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Forced expression of the cyclin B1-CDC2 complex induces proliferation in adult rat cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Knockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cyclin A2 mediates cardiomyocyte mitosis in the postmitotic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

E2F2 expression induces proliferation of terminally differentiated cardiomyocytes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Reprogramming-derived gene cocktail increases cardiomyocyte proliferation for heart regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Catheter-based Intramyocardial Injection of FGF1 or NRG1-loaded MPs Improves Cardiac Function in a Preclinical Model of Ischemia-Reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Functional screening identifies miRNAs inducing cardiac regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Direct visualization of cell division using high-resolution imaging of M-phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

In Vivo Cellular Reprogramming: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Chemical mapping of a single molecule by plasmon-enhanced Raman scattering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Robust cellular reprogramming occurs spontaneously during liver regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Recent advances in direct cardiac reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Heart repair by reprogramming non-myocytes with cardiac transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Tissue-engineered 3-dimensional (3D) microenvironment enhances the direct reprogramming of fibroblasts into cardiomyocytes by microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Vascular endothelial growth factor in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

VEGF gene therapy: therapeutic angiogenesis in the clinic and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Epicardial FSTL1 reconstitution regenerates the adult mammalian heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Molecular Imaging of Angiogenesis in Cardiac Regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Vessel formation. De novo formation of a distinct coronary vascular population in neonatal heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Endothelial plasticity drives arterial remodeling within the endocardium after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Anatomy and development of the cardiac lymphatic vasculature: Its role in injury and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Lymphangiogenesis in myocardial remodelling after infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cardiac lymphatics are heterogeneous in origin and respond to injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Selective Stimulation of Cardiac Lymphangiogenesis Reduces Myocardial Edema and Fibrosis Leading to Improved Cardiac Function Following Myocardial Infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Inflammatory processes in cardiovascular disease: a route to targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cardiac fibrosis in myocardial infarction-from repair and remodeling to regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Anti-remodeling and anti-fibrotic effects of the neuregulin-1β glial growth factor 2 in a large animal model of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Chymase inhibition prevents cardiac fibrosis and dysfunction after myocardial infarction in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Platelet-derived growth factor blockade on cardiac remodeling following infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cardiac cell therapy: lessons from clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cell therapy for cardiac repair--lessons from clinical trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Bridging the regeneration gap: genetic insights from diverse animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

AAV-mediated in vivo functional selection of tissue-protective factors against ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Heart regeneration: opportunities and challenges for drug discovery with novel chemical and therapeutic methods or agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A chemical biology approach to myocardial regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Cell delivery routes for stem cell therapy to the heart: current and future approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Hydrogel based approaches for cardiac tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The cancer paradigms of mammalian regeneration: can mammals regenerate as amphibians?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Translating stem cell research to cardiac disease therapies: pitfalls and prospects for improvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Phase II clinical research design in cardiology: learning the right lessons too well: observations and recommendations from the Cardiovascular Cell Therapy Research Network (CCTRN).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Clinical imaging in regenerative medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): weighted regression and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

SCIENTIFIC COMMUNITY. Confronting stem cell hype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Identification of splenic reservoir monocytes and their deployment to inflammatory sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Myocardial no-reflow in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Crosstalk between fibroblasts and inflammatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Left ventricular remodeling after myocardial infarction: pathophysiology and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Adrenergic nervous system in heart failure: pathophysiology and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Mechanisms of disease: apoptosis in heart failure--seeing hope in death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The neurohormonal hypothesis: a theory to explain the mechanism of disease progression in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Intracoronary Bone Marrow–Derived Progenitor Cells in Acute Myocardial Infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

RETRACTED: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Intracoronary injection of bone marrow-derived mononuclear cells early or late after acute myocardial infarction: effects on global left ventricular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Autologous mesenchymal stem cells produce concordant improvements in regional function, tissue perfusion, and fibrotic burden when administered to patients undergoing coronary artery bypass grafting: The Prospective Randomized Study of Mesenchymal S

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A randomized double-blind control study of early intra-coronary autologous bone marrow cell infusion in acute myocardial infarction: the REGENERATE-AMI clinical trial†.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Sustained delivery of insulin-like growth factor-1/hepatocyte growth factor stimulates endogenous cardiac repair in the chronic infarcted pig heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Growth hormone-releasing hormone agonists reduce myocardial infarct scar in swine with subacute ischemic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Effect of Losmapimod on Cardiovascular Outcomes in Patients Hospitalized With Acute Myocardial Infarction: A Randomized Clinical Trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Early short-term doxycycline therapy in patients with acute myocardial infarction and left ventricular dysfunction to prevent the ominous progression to adverse remodelling: the TIPTOP trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study].

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Effects of selective matrix metalloproteinase inhibitor (PG-116800) to prevent ventricular remodeling after myocardial infarction: results of the PREMIER (Prevention of Myocardial Infarction Early Remodeling) trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Myoblast transplantation for heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Intravenous immunoglobulin does not reduce left ventricular remodeling in patients with myocardial dysfunction during hospitalization after acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Epidemiology of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Late donor cardiectomy after paediatric heterotopic cardiac transplantation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Sympathetic Reinnervation Is Required for Mammalian Cardiac Regeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Pan-epicardial lineage tracing reveals that epicardium derived cells give rise to myofibroblasts and perivascular cells during zebrafish heart regeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

The evolution of regeneration: Adaptive or inherent?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Collagen reconstitution is inversely correlated with induction of limb regeneration in Ambystoma mexicanum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A Phase I, Single Ascending Dose Study of Cimaglermin Alfa (Neuregulin 1β3) in Patients With Systolic Dysfunction and Heart Failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

In vivo cardiac reprogramming contributes to zebrafish heart regeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Hemodynamic contribution of stem cell scaffolding in acute injured myocardium

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Pathophysiology of chronic heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Human embryonic stem cell-derived cardiac progenitors for severe heart failure treatment: first clinical case report: Figure 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

A Phase II, randomized, double-blind, multicenter, based on standard therapy, placebo-controlled study of the efficacy and safety of recombinant human neuregulin-1 in patients with chronic heart failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

Pexelizumab and the APEX AMI trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRD.2017.106

31 March 2020

Identifiers

DOI

10.1038/NRD.2017.106

1 reference

5 September 2017

1 reference