(Q38677840)

5 September 2017

title

Recent advances in engineering nonribosomal peptide assembly lines (English)

1 reference

5 September 2017

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26699732%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

M Winn

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26699732%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

J K Fyans

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26699732%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Y Zhuo

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26699732%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

publication date

24 December 2015

1 reference

5 September 2017

published in

Natural Product Reports

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26699732%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26699732%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26699732%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

317-347

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26699732%20AND%20SRC:MED&resulttype=core&format=json

Oritavancin: first global approval

9 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Biosynthesis of nonribosomal peptides1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Portability of epimerization domain and role of peptidyl carrier protein on epimerization activity in nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

The txtAB genes of the plant pathogen Streptomyces acidiscabies encode a peptide synthetase required for phytotoxin thaxtomin A production and pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Tailoring enzymes that modify nonribosomal peptides during and after chain elongation on NRPS assembly lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Characterization and genetic manipulation of peptide synthetases in Pseudomonas aeruginosa PAO1 in order to generate novel pyoverdines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Biological variation of microbial metabolites by precursor-directed biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Fluorobalhimycin--a new chapter in glycopeptide antibiotic research

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Auxotrophic-precursor directed biosynthesis of nonribosomal lipopeptides with modified tryptophan residues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Mutasynthesis of glycopeptide antibiotics: variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

New pacidamycin antibiotics through precursor-directed biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Gene expression enabling synthetic diversification of natural products: chemogenetic generation of pacidamycin analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Natural products to drugs: daptomycin and related lipopeptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Conjugation of fatty acids with different lengths modulates the antibacterial and antifungal activity of a cationic biologically inactive peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Inactivation of the lipopeptide antibiotic daptomycin by hydrolytic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Engineered biosynthesis of nonribosomal lipopeptides with modified fatty acid side chains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Enduracidin analogues with altered halogenation patterns produced by genetically engineered strains of Streptomyces fungicidicus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Functional analysis of the lipoglycodepsipeptide antibiotic ramoplanin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Engineered biosynthesis of enduracidin lipoglycopeptide antibiotics using the ramoplanin mannosyltransferase Ram29.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

A40926, a new glycopeptide antibiotic with anti-Neisseria activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Multiple complexes of long aliphatic N-acyltransferases lead to synthesis of 2,6-diacylated/2-acyl-substituted glycopeptide antibiotics, effectively killing vancomycin-resistant enterococcus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Glycopeptide sulfation evades resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Harnessing the synthetic capabilities of glycopeptide antibiotic tailoring enzymes: characterization of the UK-68,597 biosynthetic cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Combinatorial biosynthesis of lipopeptide antibiotics in Streptomyces roseosporus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Genetic engineering in Streptomyces roseosporus to produce hybrid lipopeptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Combinatorial biosynthesis of novel antibiotics related to daptomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Non-ribosomal peptide synthetase module fusions to produce derivatives of daptomycin in Streptomyces roseosporus

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Biosynthesis of novel Pyoverdines by domain substitution in a nonribosomal peptide synthetase of Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Decreasing the ring size of a cyclic nonribosomal peptide antibiotic by in-frame module deletion in the biosynthetic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Module extension of a non-ribosomal peptide synthetase of the glycopeptide antibiotic balhimycin produced by Amycolatopsis balhimycina

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Creating functional engineered variants of the single-module non-ribosomal peptide synthetase IndC by T domain exchange.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Biochemical and Crystallographic Analysis of Substrate Binding and Conformational Changes in Acetyl-CoA Synthetase † , ‡

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

The mechanism of domain alternation in the acyl-adenylate forming ligase superfamily member 4-chlorobenzoate: coenzyme A ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

A subdomain swap strategy for reengineering nonribosomal peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

NRPSpredictor2--a web server for predicting NRPS adenylation domain specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Biosynthesis of the (2S,3R)-3-methyl glutamate residue of nonribosomal lipopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Directed evolution can rapidly improve the activity of chimeric assembly-line enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Directed evolution of the nonribosomal peptide synthetase AdmK generates new andrimid derivatives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Engineering the substrate specificity of the DhbE adenylation domain by yeast cell surface display

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

An engineered yeast efficiently secreting penicillin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Bacillus subtilis as heterologous host for the secretory production of the non-ribosomal cyclodepsipeptide enniatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Diversification of echinomycin molecular structure by way of chemoenzymatic synthesis and heterologous expression of the engineered echinomycin biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Reconstituted biosynthesis of the nonribosomal macrolactone antibiotic valinomycin in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Targeted capture and heterologous expression of the Pseudoalteromonas alterochromide gene cluster in Escherichia coli represents a promising natural product exploratory platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Harnessing homologous recombination in vitro to generate recombinant DNA via SLIC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Enzymatic assembly of DNA molecules up to several hundred kilobases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

A stepwise increase in pristinamycin II biosynthesis by Streptomyces pristinaespiralis through combinatorial metabolic engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

A one pot, one step, precision cloning method with high throughput capability

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Tandem assembly of the epothilone biosynthetic gene cluster by in vitro site-specific recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Rapid metabolic pathway assembly and modification using serine integrase site-specific recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Refactoring the silent spectinabilin gene cluster using a plug-and-play scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Improved seamless mutagenesis by recombineering using ccdB for counterselection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Lambda red-mediated genetic manipulation of antibiotic-producing Streptomyces.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Use of the meganuclease I-SceI of Saccharomyces cerevisiae to select for gene deletions in actinomycetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

An efficient blue-white screening based gene inactivation system for Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

TALENs: a widely applicable technology for targeted genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

High-efficiency multiplex genome editing of Streptomyces species using an engineered CRISPR/Cas system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H

Directed evolution of a gatekeeper domain in nonribosomal peptide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC5NP00099H