(Q38679768)

English

Flutamide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in advanced prostatic cancer

scientific article published on August 1989

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scholarly article

1 reference

Europe PubMed Central

5 September 2017

1 reference

Europe PubMed Central

Flutamide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in advanced prostatic cancer (English)

1 reference

Europe PubMed Central

5 September 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

1

object named as

Brogden RN

1 reference

Europe PubMed Central

5 September 2017

author name string

Clissold SP

2

1 reference

Europe PubMed Central

5 September 2017

publication date

1 August 1989

1 reference

Europe PubMed Central

5 September 2017

1 reference

Europe PubMed Central

5 September 2017

38

1 reference

Europe PubMed Central

5 September 2017

2

1 reference

Europe PubMed Central

5 September 2017

185-203

1 reference

Europe PubMed Central

5 September 2017

https://scigraph.springernature.com/pub.10.2165/00003495-198938020-00003

0 references

Percutaneous penetration and metabolism of topical (14C)flutamide in men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete androgen blockade for the treatment of prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced prostatic carcinoma Flutamide therapy after conventional endocrine treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flutamide therapy for advanced prostatic cancer: a phase II study

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leuprolide versus diethylstilbestrol for metastatic prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in previously untreated patients with clinical stage D2 prostate cancer: today's therapy of choice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical evaluation of flutamide and estramustine as initial treatment of metastatic carcinoma of prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination therapy with flutamide and castration (orchiectomy or LHRH agonist): the minimal endocrine therapy in both untreated and previously treated patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Criteria for evaluating patient responses to treatment modalities for prostatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of flutamide, a nonsteroidal antiandrogen on functional maturation of the epididymis of rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of a nonsteroidal antiandrogen, flutamide, on androgen receptor dynamics and ornithine decarboxylase gene expression in mouse kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of flutamide on testosterone metabolism and the plasma levels of androgens and gonadotropins

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear uptake of androgen by human benign prostate in vitro: action of antiandrogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Flutamide or Cyproterone Acetate on Pituitary and Testicular Hormones in Normal Men

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of flutamide action on prostatic and testicular functions in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the Mechanism of the Anti-androgenic Action ofFlutamide (α-α-α-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide)in the Rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence of cardiovascular disease and death in patients receiving diethylstilbestrol for carcinoma of the prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flutamide therapy for carcinoma of the prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in plasma lipoproteins during various androgen suppression therapies in men with prostatic carcinoma: effects of orchiectomy, estrogen, and combination treatment with luteinizing hormone-releasing hormone agonist and flutamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of the circulating levels of glycoprotein hormone alpha-subunit after combined administration of a luteinizing hormone-releasing hormone (LHRH) agonist and flutamide in patients with cancer of the prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of cyproterone acetate in comparison to flutamide and megestrol acetate on the ventral prostate, seminal vesicle, and adrenal glands of adult male rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flutamide versus stilboestrol in the management of advanced prostatic cancer. A controlled prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of a non-steroidal antiandrogen, flutamide, on the hypothalamo-pituitary axis, genital tract and testis in growing male rats: endocrinological and histological data.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microsomal effects of cyproterone acetate and flutamide in rat testis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of flutamide, a nonsteroidal antiandrogen on testis and accessory genital organs of male rats: a reevaluation in prepubertal and adult rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of a New, Nonsteroid, Antiandrogen, α,α,α-Trifluoro-2-methyl-4′-nitro-m-propionotoluidide (Flutamide), in Men Following a single Oral 200 mg Dose

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the antiandrogenic/androgenic activities of flutamide, cyproterone acetate and megestrol acetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experience with flutamide in patients with advanced prostatic cancer without prior endocrine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of flutamide (SCH-13521) and diethylstilbestrol in untreated advanced prostatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flutamide in the Treatment of Metastatic Carcinoma of the Prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Complete androgen blockade (orchiectomy + flutamide) versus androgen blockade with cytostasis (orchiectomy + estramustine) in the treatment of virginal advanced prostate cancer]

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of flutamide and its major metabolites after a single oral dose and during chronic treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical effects of gonadotropin-releasing hormone analogue in metastatic carcinoma of prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of luteinizing hormone bioactivity in patients with prostatic cancer treated with an LHRH agonist and a pure antiandrogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormonal changes induced by the pure antiandrogen flutamide in postmenopausal women with advanced breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A biological profile of a nonsteroidal antiandrogen, SCH 13521 (4'-nitro-3'trifluoromethylisobutyranilide).

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of newly diagnosed metastatic prostate cancer patients with chemotherapy agents in combination with hormones versus hormones alone

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of flutamide and Emcyt in hormone-refractory metastatic prostatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics of interaction of the antiandrogen flutamide with the androgen receptor in various target tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of human skin fibroblasts to obtain potency estimates of drug binding to androgen receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens (flutamide, hydroxyflutamide, RU23908, cyproterone acetate) in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of adrenalectomy, flutamide, and leuprolide on the growth of the Dunning rat R-3327 prostatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flutamide as primary treatment for metastatic prostatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2670515

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00003495-198938020-00003

1 reference

Europe PubMed Central

5 September 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

5 September 2017

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