(Q38696318)

28747436

5 September 2017

title

The Alzheimer's Disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool (English)

1 reference

5 September 2017

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Stevan A Springer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Andrea Verhagen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Venkatasubramaniam Sundaramurthy

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Frederico Alisson-Silva

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Weiping Jiang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Pradipta Ghosh

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Ajit Varki

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

26 July 2017

1 reference

28747436

Journal of Biological Chemistry

5 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

292

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

15312-15320

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

6 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5602391/fullTextXML

inferred from PubMed Central ID database lookup

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31 August 2018

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CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.

31 August 2018

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Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta

31 August 2018

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Age-dependent roles of peroxisomes in the hippocampus of a transgenic mouse model of Alzheimer's disease

31 August 2018

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Mechanisms underlying the rapid peroxisome proliferator-activated receptor-γ-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease

31 August 2018

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A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

31 August 2018

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Peroxisomes, oxidative stress, and inflammation

31 August 2018

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Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

31 August 2018

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

31 August 2018

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

31 August 2018

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Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells

31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

31 August 2018

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31 August 2018

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31 August 2018

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31 August 2018

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ITIM-dependent endocytosis of CD33-related Siglecs: role of intracellular domain, tyrosine phosphorylation, and the tyrosine phosphatases, Shp1 and Shp2

31 August 2018

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31 August 2018

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Siglecs and their roles in the immune system

31 August 2018

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31 August 2018

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Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote

31 August 2018

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31 August 2018

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A study of CD33 (SIGLEC-3) antigen expression and function on activated human T and NK cells: two isoforms of CD33 are generated by alternative splicing

31 August 2018

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Siglecs--the major subfamily of I-type lectins

31 August 2018

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Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling

31 August 2018

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31 August 2018

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Prediction of peroxisomal targeting signal 1 containing proteins from amino acid sequence

31 August 2018

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31 August 2018

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31 August 2018

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Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease

31 August 2018

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Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2.

31 August 2018

1 reference

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Cryptic sialic acid binding lectins on human blood leukocytes can be unmasked by sialidase treatment or cellular activation

31 August 2018

1 reference

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When less is more: gene loss as an engine of evolutionary change

31 August 2018

1 reference

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Siglecs: a family of sialic-acid binding lectins

31 August 2018

1 reference

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Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

31 August 2018

1 reference

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Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease

31 August 2018

1 reference

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Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils

31 August 2018

1 reference

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Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5602391

Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5602391

Intracellular pools of transferrin receptors result from constitutive internalization of unoccupied receptors

31 August 2018

1 reference

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Basic local alignment search tool

31 August 2018

1 reference

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Import of proteins into peroxisomes and other microbodies

31 August 2018

1 reference

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Two categories of mammalian galactose-binding receptors distinguished by glycan array profiling

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M117.799346

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

21 January 2018

1 reference

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https://api.crossref.org/works/10.1074%2FJBC.M117.799346

Human-Specific Evolutionary Changes in the Biology of Siglecs

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5602391

Evidence of Toll-like receptor molecules on human platelets

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28747436

12 December 2020

inferred from PubMed ID database lookup

Purification and identification of formyl-methionyl-leucyl-phenylalanine as the major peptide neutrophil chemotactic factor produced by Escherichia coli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28747436

12 December 2020

inferred from PubMed ID database lookup

The large intracellular pool of asialoglycoprotein receptors functions during the endocytosis of asialoglycoproteins by isolated rat hepatocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28747436

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M117.799346

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28747436%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

28747436

1 reference