(Q28545832)

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TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits

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TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits (English)

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rheumatoid arthritis

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Michelle O'Laughlin

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2015

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10

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4

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e0122271

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Creative Commons Attribution 4.0 International

7 April 2015

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April 2022 Public Data File from Crossref

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Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

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Multiple loci are associated with white blood cell phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

The comparative risk of serious infections among rheumatoid arthritis patients starting or switching biological agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Associations of disease activity and treatments with mortality in men with rheumatoid arthritis: results from the VARA registry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Electronic medical records for discovery research in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Clinical value of blocking IL-6 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

A groupwise association test for rare mutations using a weighted sum statistic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Administrative codes combined with medical records based criteria accurately identified bacterial infections among rheumatoid arthritis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Development of a large-scale de-identified DNA biobank to enable personalized medicine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

A single tumour necrosis factor haplotype influences the response to adalimumab in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

The efficacy of anti-TNF in rheumatoid arthritis, a comparison between randomised controlled trials and clinical practice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

Databases of patients with early rheumatoid arthritis in the USA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

29 September 2017

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

3 June 2018

Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0122271

21 January 2018

Pfizer's first-in-class JAK inhibitor pricey for rheumatoid arthritis market

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0122271

21 January 2018

Use of genome-wide association studies for drug repositioning

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0122271

21 January 2018

CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0122271

21 January 2018

EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) study identifies fecal calprotectin, serum MMP9, and serum IL-22 as a novel combination of biomarkers for Crohn's disease activity: role of cross-sectional imaging

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0122271

21 January 2018

The CORRONA database.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0122271

21 January 2018

Reuma.pt - the rheumatic diseases portuguese register

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4388675

27 November 2018

Pfizer's JAK inhibitor sails through phase 3 in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25849893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone

1 reference

https://pubmed.ncbi.nlm.nih.gov/25849893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The North American Rheumatoid Arthritis Consortium--bringing genetic analysis to bear on disease susceptibility, severity, and outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25849893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trends in lipids and lipoproteins in US adults, 1988-2010

1 reference

https://pubmed.ncbi.nlm.nih.gov/25849893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haplotype-tagging analysis of common variants of the IL23R gene demonstrates gene-wide extent of association with IBD

1 reference

https://pubmed.ncbi.nlm.nih.gov/25849893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0122271

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2015PLoSO..1022271D

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

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