(Q43086838)

13 November 2017

CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation (English)

1 reference

systemic lupus erythematosus

13 November 2017

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14

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13 November 2017

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13 November 2017

Emiliano Marasco

2

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Nataly Manjarrez-Orduño

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object named as

Manjarrez-Orduño N

1 reference

13 November 2017

18

Gaffney PM

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13 November 2017

19

Timothy J Vyse

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13 November 2017

23

Peter K Gregersen

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13 November 2017

22

Betty Diamond

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13 November 2017

21

Lindsey A Criswell

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13 November 2017

Sharon A Chung

3

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13 November 2017

Matthew S Katz

4

1 reference

13 November 2017

Jenna F Kiridly

5

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13 November 2017

Kim R Simpfendorfer

6

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13 November 2017

Jan Freudenberg

7

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13 November 2017

David H Ballard

8

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13 November 2017

Emil Nashi

9

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13 November 2017

Thomas J Hopkins

10

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13 November 2017

Deborah S Cunninghame Graham

11

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13 November 2017

Annette T Lee

12

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13 November 2017

Marieke J H Coenen

13

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13 November 2017

Dorine W Swinkels

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13 November 2017

Robert R Graham

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13 November 2017

Timothy W Behrens

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13 November 2017

language of work or name

English

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publication date

7 October 2012

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13 November 2017

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13 November 2017

44

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13 November 2017

11

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13 November 2017

1227-1230

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https://scigraph.springernature.com/pub.10.1038/ng.2439

13 November 2017

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cites work

The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Genomics and the multifactorial nature of human autoimmune disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

METAL: fast and efficient meta-analysis of genomewide association scans

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Genetic associations of LYN with systemic lupus erythematosus

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Structural basis for the recognition of c-Src by its inactivator Csk

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

A new multipoint method for genome-wide association studies by imputation of genotypes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Association of PDCD1 genetic variation with risk and clinical manifestations of systemic lupus erythematosus in a multiethnic cohort

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

PTPN22: setting thresholds for autoimmunity

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Genetic lesions in T-cell tolerance and thresholds for autoimmunity.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

A gene atlas of the mouse and human protein-encoding transcriptomes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

Age- and gender-specific reference values of estimated GFR in Caucasians: the Nijmegen Biomedical Study.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715052

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.2439

21 January 2018

Identifiers

DOI

10.1038/NG.2439

1 reference

Dimensions Publication ID

13 November 2017

0 references

1 reference

13 November 2017

1 reference