(Q38704567)

5 September 2017

title

Ubiquitin-Related Roles of β-Arrestins in Endocytic Trafficking and Signal Transduction (English)

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5 September 2017

author name string

Pierre-Yves Jean-Charles

series ordinal

1

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5 September 2017

Vishwaesh Rajiv

series ordinal

2

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5 September 2017

Sudha K Shenoy

series ordinal

3

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5 September 2017

publication date

21 January 2016

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Journal of Cellular Physiology

5 September 2017

published in

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5 September 2017

volume

231

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5 September 2017

issue

10

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5 September 2017

page(s)

2071-2080

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Minireview: ubiquitination-regulated G protein-coupled receptor signaling and trafficking

5 September 2017

cites work

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Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting.

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Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein-coupled receptor Ste2.

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Mechanism and function of deubiquitinating enzymes

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True arrestins and arrestin-fold proteins: a structure-based appraisal

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A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation

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A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis

21 January 2018

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The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization

21 January 2018

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Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.

21 January 2018

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beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53.

21 January 2018

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Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling

21 January 2018

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Direct binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation

21 January 2018

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Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET.

21 January 2018

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Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists

21 January 2018

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Deubiquitinating enzymes: a new class of biological regulators

21 January 2018

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Beta-arrestins and cell signaling

21 January 2018

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Ubiquitin-binding domains - from structures to functions

21 January 2018

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The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein-coupled receptor lysosomal sorting

21 January 2018

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Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.

21 January 2018

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{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

21 January 2018

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Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression

21 January 2018

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Androgen action and metabolism in prostate cancer

21 January 2018

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Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.

21 January 2018

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Structural determinants of arrestin functions

21 January 2018

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Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking

21 January 2018

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MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors

21 January 2018

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A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.

21 January 2018

1 reference

Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) mediates post-endocytic trafficking of protease-activated receptor 2 and calcitonin receptor-like receptor

21 January 2018

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Regulation of endocytic clathrin dynamics by cargo ubiquitination

21 January 2018

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21 January 2018

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21 January 2018

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A new ticket for entry into budding vesicles-ubiquitin

21 January 2018

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Role of ubiquitination in endocytic trafficking of G-protein-coupled receptors

21 January 2018

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Origin and function of ubiquitin-like proteins

21 January 2018

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Regulation of ligand-independent Notch signal through intracellular trafficking

21 January 2018

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The Regulation of Multiple p53 Stress Responses is Mediated through MDM2

21 January 2018

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

1 reference

Molecular determinants of orexin receptor-arrestin-ubiquitin complex formation

21 January 2018

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Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

21 January 2018

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PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications

21 January 2018

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Crystal structure of pre-activated arrestin p44

21 January 2018

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21 January 2018

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Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress

21 January 2018

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Arrestins and protein ubiquitination

21 January 2018

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Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation.

21 January 2018

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Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer

21 January 2018

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Arrestins come of age: a personal historical perspective

21 January 2018

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Transduction of receptor signals by beta-arrestins

21 January 2018

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Mdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5

21 January 2018

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21 January 2018

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beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor

21 January 2018

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Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

21 January 2018

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Function of WW domains as phosphoserine- or phosphothreonine-binding modules

21 January 2018

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Ubiquitination and degradation of mutant p53.

21 January 2018

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Arrestins as regulators of kinases and phosphatases.

21 January 2018

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Ubiquitin and membrane protein turnover: from cradle to grave

21 January 2018

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Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4

21 January 2018

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Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting

21 January 2018

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The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4

21 January 2018

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Ubiquitin-dependent regulation of G protein-coupled receptor trafficking and signaling

21 January 2018

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Tyrosine phosphorylation of G-protein-coupled-receptor kinase 2 (GRK2) by c-Src modulates its interaction with Galphaq

21 January 2018

1 reference

HECT and RING finger families of E3 ubiquitin ligases at a glance

21 January 2018

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Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding

21 January 2018

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The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2A receptor

21 January 2018

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Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation

21 January 2018

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Proteasome-independent functions of ubiquitin in endocytosis and signaling

21 January 2018

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A genomic and functional inventory of deubiquitinating enzymes

21 January 2018

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Arrestin-mediated endocytosis of yeast plasma membrane transporters

21 January 2018

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The puzzle of TRPV4 channelopathies

21 January 2018

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Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin.

21 January 2018

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Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization

21 January 2018

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The arrestin domain-containing 3 protein regulates body mass and energy expenditure

21 January 2018

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Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2

21 January 2018

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Real-time monitoring of ubiquitination in living cells by BRET.

21 January 2018

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The role of arrestins in development

21 January 2018

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Ubiquitin-dependent sorting in endocytosis

21 January 2018

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Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals.

21 January 2018

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The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

21 January 2018

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Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors

21 January 2018

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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

21 January 2018

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Mdm2 is involved in the ubiquitination and degradation of G-protein-coupled receptor kinase 2

21 January 2018

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Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2.

21 January 2018

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Seven-transmembrane receptors and ubiquitination

21 January 2018

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Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation

21 January 2018

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Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination

21 January 2018

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Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes.

21 January 2018

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β-Arrestin-mediated receptor trafficking and signal transduction

21 January 2018

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Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

21 January 2018

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Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2

21 January 2018

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Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor

21 January 2018

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Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4

21 January 2018

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Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

21 January 2018

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Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling

21 January 2018

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Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 ubiquitylation, endocytosis, and function

21 January 2018

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Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network

21 January 2018

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β-arrestins and G protein-coupled receptor trafficking

21 January 2018

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Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer

21 January 2018

1 reference

The ubiquitin system, an immense realm

21 January 2018

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Beta-arrestin-biased ligands at seven-transmembrane receptors

21 January 2018

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Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2

21 January 2018

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Involvement of general control nonderepressible kinase 2 in cancer cell apoptosis by posttranslational mechanisms

21 January 2018

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A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling

21 January 2018

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Beta2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains

21 January 2018

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Activation-dependent conformational changes in {beta}-arrestin 2.

21 January 2018

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Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).

21 January 2018

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Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR.

21 January 2018

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The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.

21 January 2018

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beta-Arrestins facilitate ubiquitin-dependent degradation of apoptosis signal-regulating kinase 1 (ASK1) and attenuate H2O2-induced apoptosis

21 January 2018

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PKCβII inhibits the ubiquitination of β-arrestin2 in an autophosphorylation-dependent manner.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.25317

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5 September 2017

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