(Q38707618)

English

IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28411130%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21 (English)

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17 March 2020

1

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17 March 2020

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Eric S Geanes

2

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17 March 2020

Joshua Ogony

3

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17 March 2020

Fariba Behbod

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17 March 2020

Jordan Marquess

5

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17 March 2020

Kelli Valdez

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17 March 2020

William Jewell

7

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17 March 2020

Ossama Tawfik

8

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17 March 2020

Joan Lewis-Wambi

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17 March 2020

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12 April 2017

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17 March 2020

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17 March 2020

399

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17 March 2020

29-43

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17 March 2020

Interferon-induced transmembrane protein 1 (IFITM1) is required for the progression of colorectal cancer.

1 reference

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16 September 2018

Prognostic value of immunohistochemical markers in malignant thymic epithelial tumors

1 reference

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16 September 2018

Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer

1 reference

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16 September 2018

PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value

1 reference

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16 September 2018

Mouse Mammary Intraductal (MIND) Method for Transplantation of Patient Derived Primary DCIS Cells and Cell Lines

1 reference

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16 September 2018

Cancer treatment and survivorship statistics, 2016.

1 reference

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16 September 2018

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

1 reference

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16 September 2018

Interferon-induced transmembrane protein 1 (IFITM1) overexpression enhances the aggressive phenotype of SUM149 inflammatory breast cancer cells in a signal transducer and activator of transcription 2 (STAT2)-dependent manner.

1 reference

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16 September 2018

Cytoplasmic p21 is responsible for paclitaxel resistance in ovarian cancer A2780 cells

1 reference

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16 September 2018

The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry

1 reference

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16 September 2018

The pitfall of the transient, inconsistent anticancer capacity of antiestrogens and the mechanism of apparent antiestrogen resistance

1 reference

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16 September 2018

IFITM1 promotes the metastasis of human colorectal cancer via CAV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Targeting interferon response genes sensitizes aromatase inhibitor resistant breast cancer cells to estrogen-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor-positive breast cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Cytoplasmic localization of p21 protects trophoblast giant cells from DNA damage induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Interferons and their stimulated genes in the tumor microenvironment

1 reference

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16 September 2018

The tetraspanin CD81 protein increases melanoma cell motility by up-regulating metalloproteinase MT1-MMP expression through the pro-oncogenic Akt-dependent Sp1 activation signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

IFITs: Emerging Roles as Key Anti-Viral Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Interferon-induced transmembrane protein 1 regulates endothelial lumen formation during angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

IFITM proteins-cellular inhibitors of viral entry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Everolimus in combination with letrozole inhibit human breast cancer MCF-7/Aro stem cells via PI3K/mTOR pathway: an experimental study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Dual inhibition of PI3K and mTOR mitigates compensatory AKT activation and improves tamoxifen response in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

IFITM1 is a tight junction protein that inhibits hepatitis C virus entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER+/HER2-) breast cancers?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Targeting the PI3K/Akt/mTOR pathway for breast cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Influences of the interferon induced transmembrane protein 1 on the proliferation, invasion, and metastasis of the colorectal cancer SW480 cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Interferon-stimulated genes and their antiviral effector functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Understanding the mechanisms of aromatase inhibitor resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Human primary ductal carcinoma in situ (DCIS) subtype-specific pathology is preserved in a mouse intraductal (MIND) xenograft model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

MMP-10/stromelysin-2 promotes invasion of head and neck cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

p21Cip1/Waf1 protein and its function based on a subcellular localization [corrected].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Mechanisms of endocrine resistance in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Activation of CD147 with Cyclophilin A Induces the Expression of IFITM1 through ERK and PI3K in THP-1 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Examination of the expanding pathways for the regulation of p21 expression and activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Differential gene expression identified in Uigur women cervical squamous cell carcinoma by suppression subtractive hybridization

1 reference

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16 September 2018

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ

1 reference

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16 September 2018

A versatile viral system for expression and depletion of proteins in mammalian cells

1 reference

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16 September 2018

Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

p21 in cancer: intricate networks and multiple activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

16 September 2018

Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: a membrane proteomics approach

1 reference

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16 September 2018

A snapshot of microarray-generated gene expression signatures associated with ovarian carcinoma

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16 September 2018

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

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16 September 2018

Interferon-alpha and cancer: mechanisms of action and new perspectives of clinical use.

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16 September 2018

The multiple faces of caveolae

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16 September 2018

The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability

1 reference

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16 September 2018

Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation

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16 September 2018

Human interferons alpha, beta and omega

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16 September 2018

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16 September 2018

CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription

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16 September 2018

STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells

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16 September 2018

Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling.

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16 September 2018

Aromatase inhibitors: mechanism of action and role in the treatment of breast cancer

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16 September 2018

Endocrine-responsive breast cancer and strategies for combating resistance

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16 September 2018

Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

1 reference

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16 September 2018

Up-regulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation

1 reference

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16 September 2018

Multiple functions of caveolin-1.

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16 September 2018

Aromatase, aromatase inhibitors, and breast cancer

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16 September 2018

Pim-1 kinase protects hematopoietic FDC cells from genotoxin-induced death

1 reference

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16 September 2018

The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway

1 reference

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16 September 2018

An estrogen-independent MCF-7 breast cancer cell line which contains a novel 80-kilodalton estrogen receptor-related protein

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16 September 2018

An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol

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16 September 2018

Aromatase, aromatase inhibitors, and breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5530765

15 October 2018

Overexpression of IFITM1 has clinicopathologic effects on gastric cancer and is regulated by an epigenetic mechanism

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/28411130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular profiling of aromatase inhibitor-treated postmenopausal breast tumors identifies immune-related correlates of resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/28411130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular profiling to identify molecular mechanism in esophageal cancer with familial clustering

1 reference

https://pubmed.ncbi.nlm.nih.gov/28411130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CANLET.2017.04.005

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28411130%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28411130%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28411130%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

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