(Q38707728)

5 September 2017

title

Improvement of cardiovascular remodelling by chymase inhibitor (English)

1 reference

5 September 2017

2

Denan Jin

1 reference

5 September 2017

Shinji Takai

1

1 reference

5 September 2017

publication date

22 January 2016

1 reference

Clinical and Experimental Pharmacology and Physiology

5 September 2017

published in

1 reference

5 September 2017

volume

43

1 reference

5 September 2017

issue

4

1 reference

5 September 2017

page(s)

387-393

1 reference

Three-dimensional molecular modeling explains why catalytic function for angiotensin-I is different between human and rat chymases.

5 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Induction of chymase that forms angiotensin II in the monkey atherosclerotic aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Angiotensin II generation by mast cell alpha- and beta-chymases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Mouse mast cell protease-1 cleaves angiotensin I to form angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: effects of PA12 upon cardiac haemodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Big angiotensin-25: a novel glycosylated angiotensin-related peptide isolated from human urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

A novel chymase inhibitor, 4-[1-([bis-(4-methyl-phenyl)-methyl]-carbamoyl)3-(2-ethoxy-benzyl)-4-oxo-azetidine-2-yloxy]-benzoic acid (BCEAB), suppressed cardiac fibrosis in cardiomyopathic hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Src is an important mediator of extracellular signal-regulated kinase 1/2-dependent growth signaling by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Pathogenetic role of vascular angiotensin-converting enzyme in the spontaneously hypertensive rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Role of chymase-dependent angiotensin II formation in regulating blood pressure in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

ACE-versus chymase-dependent angiotensin II generation in human coronary arteries: a matter of efficiency?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase inhibition improves vascular dysfunction and survival in stroke-prone spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

A novel chymase inhibitor, 2-(5-formylamino-6-oxo-2-phenyl-1,6-dihydropyrimidine-1-yl)-N-[[,4-dioxo-1-phenyl-7-(2-pyridyloxy)]2-heptyl]acetamide (NK3201), suppressed intimal hyperplasia after balloon injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Mechanisms of arterial remodeling in hypertension: coupled roles of wall shear and intramural stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Doxycycline, a matrix metalloprotease inhibitor, reduces vascular remodeling and damage after cerebral ischemia in stroke-prone spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Increased chymase activity in internal thoracic artery of patients with hypercholesterolemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase inhibition suppresses high-cholesterol diet-induced lipid accumulation in the hamster aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Mast cell chymase inhibition reduces atherosclerotic plaque progression and improves plaque stability in ApoE−/− mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Anti-atherosclerotic effects of an angiotensin converting enzyme inhibitor and an angiotensin II antagonist in Cynomolgus monkeys fed a high-cholesterol diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Role of bone marrow renin-angiotensin system in the pathogenesis of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Association of a mast cell chymase gene variant with HDL cholesterol, but not with blood pressure in the Ohasama study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Selective angiotensin II receptor antagonism reduces insulin resistance in obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Risk of new-onset diabetes in the Losartan Intervention For Endpoint reduction in hypertension study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Improved islet morphology after blockade of the renin- angiotensin system in the ZDF rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Pancreatic beta-cells express phagocyte-like NAD(P)H oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase inhibition provides pancreatic islet protection in hamsters with streptozotocin-induced diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Advanced glycation end products activate a chymase-dependent angiotensin II-generating pathway in diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase inhibition prevents myocardial fibrosis through the attenuation of NOX4-associated oxidative stress in diabetic hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Possible roles of cardiac chymase after myocardial infarction in hamster hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Beneficial effects of cardiac chymase inhibition during the acute phase of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

An antiarrhythmic effect of a chymase inhibitor after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Impact of acute myocardial ischemia reperfusion on the tissue and blood-borne renin-angiotensin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase inhibition reduces infarction and matrix metalloproteinase-9 activation and attenuates inflammation and fibrosis after acute myocardial ischemia/reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Neuroendocrine activity in congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Impact of chymase inhibitor on cardiac function and survival after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase Inhibition Prevents Cardiac Fibrosis and Improves Diastolic Dysfunction in the Progression of Heart Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Estrogen inhibits mast cell chymase release to prevent pressure overload-induced adverse cardiac remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Chymase inhibition prevents fibronectin and myofibrillar loss and improves cardiomyocyte function and LV torsion angle in dogs with isolated mitral regurgitation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Human chymase degrades human fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Mast cell chymase induces smooth muscle cell apoptosis by a mechanism involving fibronectin degradation and disruption of focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Cardiorenal end points in a trial of aliskiren for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

Cleaved secretory leucocyte protease inhibitor as a biomarker of chymase activity in allergic airway disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2F1440-1681.12549

21 January 2018

Identifiers

DOI

10.1111/1440-1681.12549

1 reference

5 September 2017

1 reference