(Q38712275)

19 May 2018

title

Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition (English)

1 reference

19 May 2018

Ectonucleotide pyrophosphatase/phosphodiesterase 7

main subject

1 reference

GOA release 2020-03-11

zinc ion binding

1 reference

GOA release 2020-03-11

author

Alexei Gorelik

1

1 reference

19 May 2018

author name string

Fangyu Liu

2

1 reference

19 May 2018

Katalin Illes

3

1 reference

19 May 2018

Bhushan Nagar

4

1 reference

19 May 2018

language of work or name

English

0 references

publication date

14 March 2017

1 reference

19 May 2018

Journal of Biological Chemistry

published in

1 reference

19 May 2018

volume

292

1 reference

19 May 2018

issue

17

1 reference

19 May 2018

page(s)

7087-7094

1 reference

19 May 2018

Processing of X-ray diffraction data collected in oscillation mode

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23 June 2018

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23 June 2018

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23 June 2018

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Molecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke

23 June 2018

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23 June 2018

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The Cation- Box Is a Specific Phosphatidylcholine Membrane Targeting Motif

23 June 2018

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Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification

23 June 2018

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Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

23 June 2018

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23 June 2018

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Towards automated crystallographic structure refinement with phenix.refine

23 June 2018

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Computational identification and experimental characterization of substrate binding determinants of nucleotide pyrophosphatase/phosphodiesterase 7.

23 June 2018

1 reference

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Structural basis of substrate discrimination and integrin binding by autotaxin

23 June 2018

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Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

23 June 2018

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The role of bile salts in digestion

23 June 2018

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Understanding the molecular activity of alkaline sphingomyelinase (NPP7) by computer modeling.

23 June 2018

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Features and development of Coot

23 June 2018

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

23 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Phasercrystallographic software

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Alkaline sphingomyelinase: an old enzyme with novel implications

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Val-407 and Ile-408 in the beta5'-loop of pancreatic lipase mediate lipase-colipase interactions in the presence of bile salt micelles

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Intestinal alkaline sphingomyelinase hydrolyses and inactivates platelet-activating factor by a phospholipase C activity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Functional studies of human intestinal alkaline sphingomyelinase by deglycosylation and mutagenesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Pancreatic trypsin cleaves intestinal alkaline sphingomyelinase from mucosa and enhances the sphingomyelinase activity.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Purification, localization, and expression of human intestinal alkaline sphingomyelinase

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Crystal structure of the open form of dog gastric lipase in complex with a phosphonate inhibitor

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Effects of phospholipids on sphingomyelin hydrolysis induced by intestinal alkaline sphingomyelinase: an in vitro study

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Familial adenomatous polyposis is associated with a marked decrease in alkaline sphingomyelinase activity: a key factor to the unrestrained cell proliferation?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

The crystal structure of bovine bile salt activated lipase: insights into the bile salt activation mechanism

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Alkaline sphingomyelinase activity is decreased in human colorectal carcinoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Identification of an alkaline sphingomyelinase activity in human bile

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Micelle formation by bile salts. Physical-chemical and thermodynamic considerations

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5409475

Micelle Formation by Bile Salts

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M116.769273

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M116.769273

Purification of a newly identified alkaline sphingomyelinase in human bile and effects of bile salts and phosphatidylcholine on enzyme activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28292932

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enhanced colonic tumorigenesis in alkaline sphingomyelinase (NPP7) knockout mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28292932

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M116.769273

1 reference

19 May 2018

PMC publication ID

5409475

1 reference

19 May 2018

PubMed publication ID

28292932

1 reference

19 May 2018