(Q38713300)

5 September 2017

Genetic and pharmacological inhibition of vanin-1 activity in animal models of type 2 diabetes (English)

1 reference

5 September 2017

1 reference

type 2 diabetes

9 December 2023

7

Mihai G Netea

1 reference

5 September 2017

Janna A van Diepen

1

1 reference

5 September 2017

Patrick A Jansen

2

1 reference

5 September 2017

Dov B Ballak

3

1 reference

5 September 2017

Anneke Hijmans

4

1 reference

5 September 2017

Floris P J T Rutjes

5

1 reference

5 September 2017

Cees J Tack

6

1 reference

5 September 2017

Joost Schalkwijk

8

1 reference

5 September 2017

Rinke Stienstra

9

1 reference

5 September 2017

language of work or name

English

0 references

publication date

2 March 2016

1 reference

5 September 2017

1 reference

5 September 2017

6

1 reference

5 September 2017

21906

1 reference

Creative Commons Attribution 4.0 International

5 September 2017

start time

2 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/srep21906

0 references

cites work

The structure of vanin 1: a key enzyme linking metabolic disease and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

A fluorescent assay suitable for inhibitor screening and vanin tissue quantification

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Pantetheinase activity of membrane-bound Vanin-1: lack of free cysteamine in tissues of Vanin-1 deficient mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Is pantetheinase the actual identity of mouse and human vanin-1 proteins?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Regulation of leukocyte adherence and migration by glycosylphosphatidyl-inositol-anchored proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Analysis of vanin-1 upregulation and lipid accumulation in hepatocytes in response to a high-fat diet and free fatty acids.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

PPARalpha regulates the production of serum Vanin-1 by liver

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Peroxisome proliferator-activated receptor alpha target genes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

Mouse vanin-1 is cytoprotective for islet beta cells and regulates the development of type 1 diabetes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4773925

The enzymatic breakdown of pantethine to pantothenic acid and cystamine

31 August 2018

1 reference

12 December 2020

Pantethine lipomodulation: evidence for cysteamine mediation in vitro and in vivo

1 reference

12 December 2020

Vanin-1 is a key activator for hepatic gluconeogenesis

1 reference

12 December 2020

Pantethine stimulates lipolysis in adipose tissue and inhibits cholesterol and fatty acid synthesis in liver and intestinal mucosa in the normolipidemic rat

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP21906

1 reference

Dimensions Publication ID

5 September 2017

0 references

1 reference

5 September 2017

1 reference