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Phospho-ubiquitin: upending the PINK-Parkin-ubiquitin cascade
scientific article published on 2 February 2016
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scholarly article
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Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
review article
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Europe PubMed Central
title
Phospho-ubiquitin: upending the PINK-Parkin-ubiquitin cascade
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
author
Noriyuki Matsuda
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
author name string
Noriyuki Matsuda
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4885936
retrieved
5 September 2017
publication date
2 February 2016
1 reference
stated in
Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
published in
Journal of Biochemistry
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Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
volume
159
1 reference
stated in
Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
page(s)
379-385
1 reference
stated in
Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
cites work
The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Expanding the ubiquitin code through post-translational modification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Molecular mechanisms underlying PINK1 and Parkin catalyzed ubiquitylation of substrates on damaged mitochondria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1/Parkin-mediated mitophagy in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Mitophagy in yeast: Molecular mechanisms and physiological role
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Receptor-mediated mitophagy in yeast and mammalian systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Organellophagy: eliminating cellular building blocks via selective autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Ubiquitin is phosphorylated by PINK1 to activate parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1 is degraded through the N-end rule pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
The LIR motif - crucial for selective autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Structure of the human Parkin ligase domain in an autoinhibited state
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Structure of parkin reveals mechanisms for ubiquitin ligase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Autophagy: renovation of cells and tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
What genetics tells us about the causes and mechanisms of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Mechanisms of mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Structural basis for sorting mechanism of p62 in selective autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
6 September 2017
Phosphorylated ubiquitin chain is the genuine Parkin receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
14 September 2017
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
25 September 2017
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
23 June 2018
A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
23 June 2018
Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
23 June 2018
Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
23 June 2018
Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
31 August 2018
The protonophore CCCP interferes with lysosomal degradation of autophagic cargo in yeast and mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
31 August 2018
Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
31 August 2018
Neurodegenerative disease: pink, parkin and the brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4885936
retrieved
31 August 2018
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26839319
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/JB/MVV125
1 reference
stated in
Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PMCID
4885936
1 reference
stated in
Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PubMed ID
26839319
1 reference
stated in
Europe PubMed Central
PMCID
4885936
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26839319%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
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