(Q38726518)

English

Interrogation of related clinical pan-azole-resistant Aspergillus fumigatus strains: G138C, Y431C, and G434C single nucleotide polymorphisms in cyp51A, upregulation of cyp51A, and integration and activation of transposon Atf1 in the cyp51A promoter

scientific article published on 29 August 2011

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scholarly article

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11 February 2020

Interrogation of related clinical pan-azole-resistant Aspergillus fumigatus strains: G138C, Y431C, and G434C single nucleotide polymorphisms in cyp51A, upregulation of cyp51A, and integration and activation of transposon Atf1 in the cyp51A promoter (English)

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11 February 2020

Aspergillus fumigatus

0 references

ABC multidrug transporter

1 reference

5 February 2019

14-alpha sterol demethylase

1 reference

6 February 2019

ABC multidrug transporter

1 reference

6 February 2019

single-nucleotide polymorphism

1 reference

based on heuristic

inferred from title

David W. Denning

7

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11 February 2020

3

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11 February 2020

Dominique Sanglard

6

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11 February 2020

author name string

Ahmed M Albarrag

1

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11 February 2020

Michael J Anderson

2

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11 February 2020

Geoff D Robson

4

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11 February 2020

Peter A Warn

5

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11 February 2020

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publication date

29 August 2011

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11 February 2020

Antimicrobial Agents and Chemotherapy

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11 February 2020

55

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11 February 2020

11

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11 February 2020

5113-5121

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11 February 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3195044/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Global burden of chronic pulmonary aspergillosis as a sequel to pulmonary tuberculosis

1 reference

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Acquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection.

1 reference

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Clinical characteristics and treatment outcomes of chronic necrotizing pulmonary aspergillosis: a review of 43 cases

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An A643T mutation in the transcription factor Upc2p causes constitutive ERG11 upregulation and increased fluconazole resistance in Candida albicans

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Azole-resistance in Aspergillus: proposed nomenclature and breakpoints

1 reference

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Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods

1 reference

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Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism

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6 September 2017

Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus

1 reference

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6 September 2017

Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America

1 reference

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6 September 2017

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

1 reference

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6 September 2017

Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.

1 reference

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6 September 2017

Aspergillus lentulus sp. nov., a new sibling species of A. fumigatus

1 reference

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6 September 2017

In vitro evolution of itraconazole resistance in Aspergillus fumigatus involves multiple mechanisms of resistance

1 reference

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6 September 2017

Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole.

1 reference

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6 September 2017

Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase

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6 September 2017

Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species

1 reference

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6 September 2017

Resistance to itraconazole in Aspergillus nidulans and Aspergillus fumigatus is conferred by extra copies of the A. nidulans P-450 14alpha-demethylase gene, pdmA.

1 reference

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6 September 2017

Microsatellite markers for typing Aspergillus fumigatus isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195044

6 September 2017

Itraconazole resistance in Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195044

6 September 2017

Molecular typing by random amplification of polymorphic DNA and M13 southern hybridization of related paired isolates of Aspergillus fumigatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195044

6 September 2017

Epidemiological cutoffs and cross-resistance to azole drugs in Aspergillus fumigatus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195044

14 September 2017

A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus

1 reference

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Variability of germinative potential among pathogenic species of Aspergillus

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Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure

1 reference

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23 June 2018

Characterisation of Aft1 a Fot1/Pogo type transposon of Aspergillus fumigatus

1 reference

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23 June 2018

A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

1 reference

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Choline- and acetylcholine-induced changes in the morphology of Fusarium graminearum: evidence for the involvement of the choline transport system and acetylcholinesterase.

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Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009.

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Cryptic speciation in the cosmopolitan and clonal human pathogenic fungus Aspergillus fumigatus

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Correlation between in vitro growth rate and in vivo virulence in Aspergillus fumigatus

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31 August 2018

Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma

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1 reference

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31 August 2018

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31 August 2018

EUCAST Technical Note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia–forming moulds

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1 reference

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based on heuristic

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Identifiers

10.1128/AAC.00517-11

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Europe PubMed Central

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11 February 2020

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Europe PubMed Central

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11 February 2020

1 reference

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11 February 2020

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