(Q38736464)

14 July 2018

title

Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer (English)

1 reference

14 July 2018

author name string

Ting Ni

1

1 reference

14 July 2018

Xiao-Yan Li

2

1 reference

14 July 2018

Na Lu

3

1 reference

14 July 2018

Teng An

4

1 reference

14 July 2018

Zhi-Ping Liu

5

1 reference

14 July 2018

Rong Fu

6

1 reference

14 July 2018

Wen-Cong Lv

7

1 reference

14 July 2018

Yi-Wei Zhang

8

1 reference

14 July 2018

Xiao-Jun Xu

9

1 reference

14 July 2018

R Grant Rowe

10

1 reference

14 July 2018

Yong-Shun Lin

11

1 reference

14 July 2018

Amanda Scherer

12

1 reference

14 July 2018

Tamar Feinberg

13

1 reference

14 July 2018

Xiao-Qi Zheng

14

1 reference

14 July 2018

Bao-An Chen

15

1 reference

14 July 2018

X Shirley Liu

16

1 reference

14 July 2018

Qing-Long Guo

17

1 reference

14 July 2018

Zhao-Qiu Wu

18

1 reference

14 July 2018

Stephen J Weiss

19

1 reference

14 July 2018

publication date

17 October 2016

1 reference

14 July 2018

published in

Nature Cell Biology

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14 July 2018

volume

18

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14 July 2018

issue

11

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14 July 2018

page(s)

1221-1232

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14 July 2018

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

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15 July 2018

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Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

15 July 2018

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Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

15 July 2018

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Shp2 signaling suppresses senescence in PyMT-induced mammary gland cancer in mice.

15 July 2018

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15 July 2018

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Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages

15 July 2018

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Transient SNAIL1 expression is necessary for metastatic competence in breast cancer

15 July 2018

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Cooperative actions of p21WAF1 and p53 induce Slug protein degradation and suppress cell invasion

15 July 2018

1 reference

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MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors

15 July 2018

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A Snail1/Notch1 signalling axis controls embryonic vascular development.

15 July 2018

1 reference

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Oncogenic roles of EMT-inducing transcription factors

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

p53 in cell invasion, podosomes, and invadopodia

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin β

15 July 2018

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A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis

15 July 2018

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Molecular mechanisms of epithelial-mesenchymal transition

15 July 2018

1 reference

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TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Collective invasion in breast cancer requires a conserved basal epithelial program

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Differential role of Snail1 and Snail2 zinc fingers in E-cadherin repression and epithelial to mesenchymal transition

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

The epigenetics of epithelial-mesenchymal plasticity in cancer

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Epithelial plasticity: a common theme in embryonic and cancer cells.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Nuclear expression of snail is an independent negative prognostic factor in human breast cancer.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Inhibition of Snail1-DNA-PKcs protein-protein interface sensitizes cancer cells and inhibits tumor metastasis

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

The twist box domain is required for Twist1-induced prostate cancer metastasis

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Mutual regulation between DNA-PKcs and Snail1 leads to increased genomic instability and aggressive tumor characteristics.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

A "twist box" code of p53 inactivation: twist box: p53 interaction promotes p53 degradation

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Interactions between cancer stem cells and their niche govern metastatic colonization

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

TP53 mutations in human cancers: origins, consequences, and clinical use

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Senescence in tumours: evidence from mice and humans

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Epithelial-mesenchymal transitions in development and disease

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Induction of a MT1-MMP and MT2-MMP-dependent basement membrane transmigration program in cancer cells by Snail1.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Blocking of p53-Snail binding, promoted by oncogenic K-Ras, recovers p53 expression and function

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Twist and p53 reciprocally regulate target genes via direct interaction

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

The epithelial-mesenchymal transition generates cells with properties of stem cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Acetylation is indispensable for p53 activation

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Generation of a functional mammary gland from a single stem cell

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Cancer development induced by graded expression of Snail in mice.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

The transcriptional repressor Snail promotes mammary tumor recurrence

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Regulation of the p300 HAT domain via a novel activation loop.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Correlation of Snail expression with histological grade and lymph node status in breast carcinomas

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6038146

Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB3425

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB3425

Different levels of Twist1 regulate skin tumor initiation, stemness, and progression

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27749822

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCB3425

1 reference

14 July 2018

Dimensions Publication ID

0 references

1 reference

14 July 2018

PubMed publication ID

27749822

1 reference

14 July 2018