(Q38746127)

English

Histone Deacetylase Inhibitor RGFP109 Overcomes Temozolomide Resistance by Blocking NF-κB-Dependent Transcription in Glioblastoma Cell Lines

scientific article published on 08 September 2016

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 September 2017

Histone Deacetylase Inhibitor RGFP109 Overcomes Temozolomide Resistance by Blocking NF-κB-Dependent Transcription in Glioblastoma Cell Lines (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

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author name string

Zong-Yang Li

1

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Europe PubMed Central

PubMed publication ID

6 September 2017

Qing-Zhong Li

2

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Lei Chen

3

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Bao-Dong Chen

4

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Bo Wang

5

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Europe PubMed Central

PubMed publication ID

6 September 2017

Xie-Jun Zhang

6

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Wei-Ping Li

7

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

publication date

8 September 2016

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Europe PubMed Central

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6 September 2017

Neurochemical Research

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Europe PubMed Central

PubMed publication ID

6 September 2017

41

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Europe PubMed Central

PubMed publication ID

6 September 2017

12

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6 September 2017

3192-3205

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Europe PubMed Central

PubMed publication ID

6 September 2017

https://scigraph.springernature.com/pub.10.1007/s11064-016-2043-5

0 references

Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

NF-kappaB and STAT3 signaling in glioma: targets for future therapies

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Regulation of NF-κB Action by Reversible Acetylation

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Good cop, bad cop: the different faces of NF-kappaB

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Transcriptional activation by NF-kappaB requires multiple coactivators

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Duration of nuclear NF-kappaB action regulated by reversible acetylation

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

RGFP109, a histone deacetylase inhibitor attenuates L-DOPA-induced dyskinesia in the MPTP-lesioned marmoset: a proof-of-concept study

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Curcumin induces G2/M cell cycle arrest in a p53-dependent manner and upregulates ING4 expression in human glioma

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Histone deacetylase: a regulator of transcription

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Identification of novel isoform-selective inhibitors within class I histone deacetylases

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Stimulus specificity of gene expression programs determined by temporal control of IKK activity

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Regulation at multiple levels of NF-kappaB-mediated transactivation by protein acetylation

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Histone acetyltransferases

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

The regulation of gene activity by histones and the histone deacetylase RPD3.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Enhanced radiation-induced cell killing and prolongation of gammaH2AX foci expression by the histone deacetylase inhibitor MS-275.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Experimental therapy of malignant gliomas using the inhibitor of histone deacetylase MS-275.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Solution structure and NMR characterization of the binding to methylated histone tails of the plant homeodomain finger of the tumour suppressor ING4

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Function of the ING family of PHD proteins in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Biological functions of the ING family tumor suppressors

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Nuclear localization signal of ING4 plays a key role in its binding to p53.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas

1 reference

https://api.crossref.org/works/10.1007%2FS11064-016-2043-5

21 January 2018

Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2

1 reference

https://pubmed.ncbi.nlm.nih.gov/27632183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide

1 reference

https://pubmed.ncbi.nlm.nih.gov/27632183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

1 reference

https://pubmed.ncbi.nlm.nih.gov/27632183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27632183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of NF-kappaB action by reversible acetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27632183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-016-2043-5

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

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