(Q38749027)

English

γ-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules

scientific article published on 30 August 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

γ-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules (English)

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Sahdeo Prasad

1

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Subash C Gupta

2

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Amit K Tyagi

3

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Bharat B Aggarwal

4

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

language of work or name

0 references

publication date

30 August 2016

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

British Journal of Cancer

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

115

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

7

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

814-824

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

copyright license

Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International

30 August 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Global cancer statistics, 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Cancer statistics, 2015

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Prevention and Treatment of Colorectal Cancer by Natural Agents From Mother Nature

1 reference

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1 October 2017

Regorafenib for gastrointestinal malignancies : from preclinical data to clinical results of a novel multi-target inhibitor

1 reference

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1 October 2017

Cotransfection of survivin and CD44v3 short hairpin RNAs affects proliferation, apoptosis, and invasiveness of colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Bevacizumab in colorectal cancer: current and future directions

1 reference

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1 October 2017

Development and validation of a sensitive LC/MS/MS method for the determination of γ-tocotrienol in rat plasma: application to pharmacokinetic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Resistance to EGFR-targeted therapy: a family affair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Tocotrienols fight cancer by targeting multiple cell signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

γ-Tocotrienol induces growth arrest through a novel pathway with TGFβ2 in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Differential suppression of proliferation in MCF-7 and MDA-MB-231 breast cancer cells exposed to alpha-, gamma- and delta-tocotrienols is accompanied by altered expression of oxidative stress modulatory enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

NF-kappaB and cancer: how intimate is this relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Suppression of NF-kappabeta signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Specific accumulation of gamma- and delta-tocotrienols in tumor and their antitumor effect in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Reduction of DNA damage in older healthy adults by Tri E Tocotrienol supplementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

In vivo angiogenesis is suppressed by unsaturated vitamin E, tocotrienol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

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Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

1 reference

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Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

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Tumor suppressive effects of tocotrienol in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Gamma-tocotrienol inhibits neoplastic mammary epithelial cell proliferation by decreasing Akt and nuclear factor kappaB activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Tocotrienol: the natural vitamin E to defend the nervous system?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

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Induction of cytotoxicity in human lung adenocarcinoma cells by 6-O-carboxypropyl-alpha-tocotrienol, a redox-silent derivative of alpha-tocotrienol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5046209

1 October 2017

Tocotrienols: constitutional effects in aging and disease

1 reference

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Clinical Pharmacokinetics of Antioxidants and Their Impact on Systemic Oxidative Stress

1 reference

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Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status

1 reference

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Assay for redox-sensitive transcription factor

1 reference

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The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract

1 reference

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Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice.

1 reference

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1 reference

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31 August 2018

Disruption of mitochondria during tocotrienol-induced apoptosis in MDA-MB-231 human breast cancer cells

1 reference

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Gamma-tocopherol inhibits human cancer cell cycle progression and cell proliferation by down-regulation of cyclins

1 reference

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31 August 2018

Lowering of serum cholesterol in hypercholesterolemic humans by tocotrienols (palmvitee)

1 reference

https://pubmed.ncbi.nlm.nih.gov/27575851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The enhancement of the oral bioavailability of γ-tocotrienol in mice by γ-cyclodextrin inclusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/27575851

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/27575851

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based on heuristic

inferred from PubMed ID database lookup

A comparison of tocopherol and tocotrienol for the chemoprevention of chemically induced rat mammary tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/27575851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time trends of mortality from colorectal cancer in the United States: a birth-cohort analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27575851

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJC.2016.257

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

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