(Q38772655)

English

Early Secreted Antigenic Target of 6 kDa of Mycobacterium tuberculosis Stimulates Macrophage Chemoattractant Protein-1 Production by Macrophages and Its Regulation by p38 Mitogen-Activated Protein Kinases and Interleukin-4.

scientific article published on 7 May 2016

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scholarly article

1 reference

Europe PubMed Central

6 September 2017

Early Secreted Antigenic Target of 6 kDa of Mycobacterium tuberculosis Stimulates Macrophage Chemoattractant Protein-1 Production by Macrophages and Its Regulation by p38 Mitogen-Activated Protein Kinases and Interleukin-4. (English)

1 reference

Europe PubMed Central

6 September 2017

Mycobacterium tuberculosis

1 reference

based on heuristic

inferred from title

author name string

J Ma

1

1 reference

Europe PubMed Central

6 September 2017

B-G Jung

2

1 reference

Europe PubMed Central

6 September 2017

N Yi

3

1 reference

Europe PubMed Central

6 September 2017

B Samten

4

1 reference

Europe PubMed Central

6 September 2017

publication date

7 May 2016

1 reference

Europe PubMed Central

6 September 2017

Scandinavian Journal of Immunology

1 reference

Europe PubMed Central

6 September 2017

84

1 reference

Europe PubMed Central

6 September 2017

1

1 reference

Europe PubMed Central

6 September 2017

39-48

1 reference

Europe PubMed Central

6 September 2017

Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature

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Reconsidering adjuvant immunotherapy for tuberculosis

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Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages

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Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

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The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

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A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion

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Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation

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Novel human immunodeficiencies reveal the essential role of type-I cytokines in immunity to intracellular bacteria

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Early secreted antigenic target of 6-kDa protein of Mycobacterium tuberculosis primes dendritic cells to stimulate Th17 and inhibit Th1 immune responses

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Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis

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The ESAT-6 protein of Mycobacterium tuberculosis interacts with beta-2-microglobulin (β2M) affecting antigen presentation function of macrophage

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Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue

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Expression and secretion of chemotactic cytokines IL-8 and MCP-1 by human endothelial cells after Rickettsia rickettsii infection: regulation by nuclear transcription factor NF-kappaB.

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Monocyte chemoattractant protein-1 (MCP-1): an overview

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CCL2 responses to Mycobacterium tuberculosis are associated with disease severity in tuberculosis

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A functional promoter polymorphism in monocyte chemoattractant protein-1 is associated with increased susceptibility to pulmonary tuberculosis.

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MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms

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The isolation and characterization of murine macrophages

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ESAT-6 inhibits production of IFN-gamma by Mycobacterium tuberculosis-responsive human T cells

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Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

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Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

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Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications

1 reference

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Protein secretion systems in Mycobacteria.

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Early secreted antigenic target of 6 kDa (ESAT-6) protein of Mycobacterium tuberculosis induces interleukin-8 (IL-8) expression in lung epithelial cells via protein kinase signaling and reactive oxygen species

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Regulation of gene expression by PI3K in mouse growth plate chondrocytes

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ESAT-6 induced COX-2 expression involves coordinated interplay between PI3K and MAPK signaling.

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21 January 2018

The Mycobacterium tuberculosis early secreted antigenic target of 6 kDa inhibits T cell interferon-γ production through the p38 mitogen-activated protein kinase pathway

1 reference

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Tumor necrosis factor and tuberculosis

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p38 MAPK regulates IL-1beta induced IL-6 expression through mRNA stability in osteoblasts

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Increased release of interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha by bronchoalveolar cells lavaged from involved sites in pulmonary tuberculosis

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Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load

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Role of TNF-Alpha, IFN-Gamma, and IL-10 in the Development of Pulmonary Tuberculosis

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The IL-13/IL-4Rα axis is involved in tuberculosis-associated pathology

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Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system

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21 January 2018

MKK3/6-p38 MAPK signaling is required for IL-1beta and TNF-alpha-induced RANKL expression in bone marrow stromal cells

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Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP

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IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway.

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Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1.

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Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth

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Impaired dendritic cell differentiation of CD16-positive monocytes in tuberculosis: role of p38 MAPK.

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The role of p38 MAPK in rhinovirus-induced monocyte chemoattractant protein-1 production by monocytic-lineage cells

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Thrombin induces MCP-1 expression through Rho-kinase and subsequent p38MAPK/NF-κB signaling pathway activation in vascular endothelial cells.

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p38 MAP-kinases pathway regulation, function and role in human diseases

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The regulation of Th1 responses by the p38 MAPK

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Role of MCP-1 in tumor necrosis factor-alpha-induced endothelial dysfunction in type 2 diabetic mice

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T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis.

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Th2 cytokines in susceptibility to tuberculosis.

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Cloning of interleukin-4 delta2 splice variant (IL-4delta2) in chimpanzee and cynomolgus macaque: phylogenetic analysis of delta2 splice variant appearance, and implications for the study of IL-4-driven immune processes

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Critical role of p38 MAPK in IL-4-induced alternative activation of peritoneal macrophages.

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Mycobacterium tuberculosis directs T helper 2 cell differentiation by inducing interleukin-1β production in dendritic cells.

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ESAT-6- and CFP-10-specific Th1, Th22 and Th17 cells in tuberculous pleurisy may contribute to the local immune response against Mycobacterium tuberculosis infection

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Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

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Identifiers

10.1111/SJI.12447

1 reference

Europe PubMed Central

6 September 2017

1 reference

Europe PubMed Central

6 September 2017

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