(Q38781435)

6 September 2017

C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress (English)

1 reference

C9orf72-SMCR8 complex subunit

6 September 2017

1 reference

GOA release 2020-03-11

stress granule assembly

1 reference

GOA release 2020-03-11

Smita Saxena

4

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author name string

Niran Maharjan

series ordinal

1

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6 September 2017

Christina Künzli

series ordinal

2

1 reference

6 September 2017

Kilian Buthey

series ordinal

3

1 reference

6 September 2017

language of work or name

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1 April 2016

1 reference

6 September 2017

Molecular Neurobiology

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6 September 2017

54

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6 September 2017

4

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6 September 2017

3062-3077

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https://scigraph.springernature.com/pub.10.1007/s12035-016-9850-1

6 September 2017

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cites work

Amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

The prevalence of frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Clinical and psychometric distinction of frontotemporal and Alzheimer dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Cognitive impairment in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Dementia and cognitive impairment in amyotrophic lateral sclerosis: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

The overlap of amyotrophic lateral sclerosis and frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Trypan blue exclusion test of cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Stress granules: sites of mRNA triage that regulate mRNA stability and translatability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Discovery of Novel DENN Proteins: Implications for the Evolution of Eukaryotic Intracellular Membrane Structures and Human Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

The product of C9orf72, a gene strongly implicated in neurodegeneration, is structurally related to DENN Rab-GEFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Network organization of the human autophagy system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Profilin 1 associates with stress granules and ALS-linked mutations alter stress granule dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

SMN deficiency reduces cellular ability to form stress granules, sensitizing cells to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Loss of function of C9orf72 causes motor deficits in a zebrafish model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9850-1

10.1007/S12035-016-9850-1

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

6 September 2017

0 references

1 reference