(Q38807251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Modern approaches to accelerate discovery of new antischistosomal drugs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Bruno J. Neves

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Carolina Horta Andrade

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

2

Eugene Muratov

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

author name string

Renato Beilner Machado

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

language of work or name

English

0 references

publication date

3 May 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Drug Discovery

1 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

page(s)

557-567

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

Effect of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad: a community study [corrected].

1 April 2020

cites work

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Praziquantel, a new broad-spectrum antischistosomal agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Molecular, biochemical, and morphometric characterization of Fasciola species potentially causing zoonotic disease in Egypt

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Schistosomiasis: from drug deployment to drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Microgeographic Population Genetic Structure of Baylisascaris procyonis (Nematoda: Ascaroidae) in Western Michigan Indicates the Grand River Is a Barrier to Gene Flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

In vitro and in vivo trematode models for chemotherapeutic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Innovative lead discovery strategies for tropical diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The genome of the blood fluke Schistosoma mansoni

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The Schistosoma japonicum genome reveals features of host-parasite interplay

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Whole-genome sequence of Schistosoma haematobium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

HTS and hit finding in academia--from chemical genomics to drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The promise of open innovation in drug discovery: an industry perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The essential roles of chemistry in high-throughput screening triage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Comparative analysis of DNA alkylation by conjugates between pyrrole-imidazole hairpin polyamides and chlorambucil or seco-CBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Isothermal microcalorimetry to study drugs against Schistosoma mansoni

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

A novel high throughput assay for anthelmintic drug screening and resistance diagnosis by real-time monitoring of parasite motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Viability of developmental stages of Schistosoma mansoni quantified with xCELLigence worm real-time motility assay (xWORM).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Segmenting the etiological agent of schistosomiasis for high-content screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The QDREC web server: determining dose-response characteristics of complex macroparasites in phenotypic drug screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

WormAssay: a novel computer application for whole-plate motion-based screening of macroscopic parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Fluorescence/luminescence-based markers for the assessment of Schistosoma mansoni schistosomula drug assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Comparison of microscopy and Alamar blue reduction in a larval based assay for schistosome drug screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Proteolytic profiling and comparative analyses of active trypsin-like serine peptidases in preimaginal stages of Culex quinquefasciatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Lactate as a novel quantitative measure of viability in Schistosoma mansoni drug sensitivity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Maximizing computational tools for successful drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

PubChem's BioAssay Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

ChEMBL: a large-scale bioactivity database for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Exploiting open data: a new era in pharmacoinformatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Role of Open Source Tools and Resources in Virtual Screening for Drug Discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The holistic integration of virtual screening in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

How far can virtual screening take us in drug discovery?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Hit identification and optimization in virtual screening: practical recommendations based on a critical literature analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Discovery of inhibitors of Schistosoma mansoni HDAC8 by combining homology modeling, virtual screening, and in vitro validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

3-oxoacyl-ACP reductase from Schistosoma japonicum: integrated in silico-in vitro strategy for discovering antischistosomal lead compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Aldose reductase from Schistosoma japonicum: crystallization and structure-based inhibitor screening for discovering antischistosomal lead compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Discovery of new inhibitors of Schistosoma mansoni PNP by pharmacophore-based virtual screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Discovery of Potent Inhibitors of Schistosoma mansoni NAD⁺ Catabolizing Enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Target-based molecular modeling strategies for schistosomiasis drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Structure-based virtual screening for drug discovery: principles, applications and recent advances.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Molecular docking and structure-based drug design strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Receptor-based virtual screening protocol for drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Methods and applications of structure based pharmacophores in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Pharmacophore modelling: a forty year old approach and its modern synergies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Recent approaches to chemical discovery and development against malaria and the neglected tropical diseases human African trypanosomiasis and schistosomiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

In silico repositioning-chemogenomics strategy identifies new drugs with potential activity against multiple life stages of Schistosoma mansoni

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

State-of-the-art in ligand-based virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

An overview of molecular fingerprint similarity search in virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Molecular fingerprint similarity search in virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Methods for generating and applying pharmacophore models as virtual screening filters and for bioactivity profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The importance of discerning shape in molecular pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Recent trends and applications in 3D virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Discovery of isoquinolinone indole acetic acids as antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Identifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival Forests

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Per aspera ad astra: application of Simplex QSAR approach in antiviral research

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Protein secondary structure prediction with SPARROW.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Virtual screening strategies in medicinal chemistry: the state of the art and current challenges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

A quality alert and call for improved curation of public chemistry databases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Trust, but verify: on the importance of chemical structure curation in cheminformatics and QSAR modeling research

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Curation of chemogenomics data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Oversampling to overcome overfitting: exploring the relationship between data set composition, molecular descriptors, and predictive modeling methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

QSAR modeling of imbalanced high-throughput screening data in PubChem

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Virtual screening of bioassay data

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Is the sigma2 receptor a histone binding protein?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The effect of ligand-based tautomer and protomer prediction on structure-based virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Accommodating Protein Flexibility for Structure-Based Drug Design

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Molecular dynamics simulations of protein dynamics and their relevance to drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

The future of molecular dynamics simulations in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Software and resources for computational medicinal chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Induced fit docking, and the use of QM/MM methods in docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Assessing the performance of 3D pharmacophore models in virtual screening: how good are they?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Best Practices for QSAR Model Development, Validation, and Exploitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

ADMET in silico modelling: towards prediction paradise?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Pred-hERG: A Novel web-Accessible Computational Tool for Predicting Cardiac Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Combination of ligand- and structure-based methods in virtual screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Virtual screening strategies in drug discovery: a critical review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

New Vaccines for the World's Poorest People

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Existing and Developing Approaches for QSAR Analysis of Mixtures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F17460441.2016.1178230

Benchmarking sets for molecular docking

21 January 2018

1 reference

12 December 2020

Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme

1 reference

12 December 2020

Recognizing pitfalls in virtual screening: a critical review

1 reference

12 December 2020

Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula

1 reference

12 December 2020

Susceptibility or resistance of praziquantel in human schistosomiasis: a review

1 reference

12 December 2020

Schistosomes: challenges in compound screening

1 reference

12 December 2020

Automated imaging and other developments in whole-organism anthelmintic screening

1 reference

12 December 2020

QSAR modeling: where have you been? Where are you going to?

1 reference

12 December 2020

Human schistosomiasis

1 reference

12 December 2020

Shape-based virtual screening with volumetric aligned molecular shapes

1 reference

12 December 2020

Anthelmintic drug discovery: into the future

1 reference

12 December 2020

Protein Flexibility in Docking-Based Virtual Screening: Discovery of Novel Lymphoid-Specific Tyrosine Phosphatase Inhibitors Using Multiple Crystal Structures

1 reference

12 December 2020

Short report: diminished susceptibility to praziquantel in a Senegal isolate of Schistosoma mansoni.

1 reference

12 December 2020

Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel.

1 reference

12 December 2020

Ceftobiprole - a case study

1 reference

13 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1080/17460441.2016.1178230

Identifiers

DOI

10.1080/17460441.2016.1178230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073973%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

27073973

1 reference