(Q38808822)

6 September 2017

Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells (English)

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6 September 2017

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Shun Fang

1

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6 September 2017

Hongyi Gao

2

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6 September 2017

Yue Tong

3

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6 September 2017

Jie Yang

4

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6 September 2017

Ruixiang Tang

5

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6 September 2017

Yuchun Niu

6

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6 September 2017

Man Li

7

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6 September 2017

Linlang Guo

8

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6 September 2017

2 November 2015

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6 September 2017

Laboratory Investigation

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6 September 2017

96

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6 September 2017

1

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6 September 2017

60-68

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https://scigraph.springernature.com/pub.10.1038/labinvest.2015.123

6 September 2017

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Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

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Long noncoding RNA HOTAIR is relevant to cellular proliferation, invasiveness, and clinical relapse in small-cell lung cancer

21 January 2018

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DNA methylation profiling in the clinic: applications and challenges

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SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15.

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Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer

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IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer.

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IGFBP-3 methylation-derived deficiency mediates the resistance to cisplatin through the activation of the IGFIR/Akt pathway in non-small cell lung cancer.

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HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer).

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Downregulation of HOXA1 gene affects small cell lung cancer cell survival and chemoresistance under the regulation of miR-100.

21 January 2018

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Transcriptional activation of signal transducer and activator of transcription (STAT) 3 and STAT5B partially mediate homeobox A1-stimulated oncogenic transformation of the immortalized human mammary epithelial cell.

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HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells.

21 January 2018

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The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1) expression

21 January 2018

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Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL.

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Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing.

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

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Correlation of MTDH/AEG-1 and HOTAIR Expression with Metastasis and Response to Treatment in Sarcoma Patients

21 January 2018

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12 December 2020

Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma

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12 December 2020

Overexpression of HOXA1 correlates with poor prognosis in patients with hepatocellular carcinoma

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12 December 2020

Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas.

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12 December 2020

Small-cell lung cancer

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12 December 2020

10.1038/LABINVEST.2015.123

Identifiers

DOI

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Dimensions Publication ID

6 September 2017

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