(Q38810847)

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Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism.

scientific article published on 17 December 2015

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scholarly article

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Europe PubMed Central

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2 March 2020

Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26680596%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Juan Carlos Espín

5

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2 March 2020

Antonio González-Sarrías

1

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2 March 2020

María A Nuñez-Sánchez

2

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2 March 2020

Rocio Garcia Villalba

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2 March 2020

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Francisco A Tomás-Barberán

4

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2 March 2020

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17 December 2015

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2 March 2020

European Journal of Nutrition

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2 March 2020

56

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2 March 2020

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2 March 2020

831-841

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2 March 2020

https://scigraph.springernature.com/pub.10.1007/s00394-015-1131-7

0 references

The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy-6H-dibenzopyran-6-one derivatives by the colonic microflora of healthy humans

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts, and oak-aged wine in humans: identification of biomarkers and individual variability

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Ellagitannins, ellagic acid and vascular health.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Biological significance of urolithins, the gut microbial ellagic Acid-derived metabolites: the evidence so far

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Gene expression, cell cycle arrest and MAPK signalling regulation in Caco-2 cells exposed to ellagic acid and its metabolites, urolithins.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

The ellagic acid-derived gut microbiota metabolite, urolithin A, potentiates the anticancer effects of 5-fluorouracil chemotherapy on human colon cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Colon cancer chemopreventive activities of pomegranate ellagitannins and urolithins

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Phase-II metabolism limits the antiproliferative activity of urolithins in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Intestinal ellagitannin metabolites ameliorate cytokine-induced inflammation and associated molecular markers in human colon fibroblasts.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP).

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

UV and MS identification of Urolithins and Nasutins, the bioavailable metabolites of ellagitannins and ellagic acid in different mammals.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Time course production of urolithins from ellagic acid by human gut microbiota.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Influence of gut microbiota-derived ellagitannins' metabolites urolithins on pro-inflammatory activities of human neutrophils.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

The ellagic acid derivative 4,4'-di-O-methylellagic acid efficiently inhibits colon cancer cell growth through a mechanism involving WNT16.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Cancer chemotherapy and drug metabolism.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Intestinal and hepatic glucuronidation of flavonoids

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Differential apoptosis-inducing effect of quercetin and its glycosides in human promyeloleukemic HL-60 cells by alternative activation of the caspase 3 cascade

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Pomegranate ellagitannin-derived compounds exhibit antiproliferative and antiaromatase activity in breast cancer cells in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Dissimilar in vitro and in vivo effects of ellagic acid and its microbiota-derived metabolites, urolithins, on the cytochrome P450 1A1.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

NF-kappaB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts.

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Urolithins, ellagic acid-derived metabolites produced by human colonic microflora, exhibit estrogenic and antiestrogenic activities

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Urolithins at physiological concentrations affect the levels of pro-inflammatory cytokines and growth factor in cultured cardiac cells in hyperglucidic conditions

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Interindividual variability in the human metabolism of ellagic acid: Contribution of Gordonibacter to urolithin production

1 reference

https://api.crossref.org/works/10.1007%2FS00394-015-1131-7

21 January 2018

Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours

1 reference

https://pubmed.ncbi.nlm.nih.gov/26680596

12 December 2020

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Identifiers

10.1007/S00394-015-1131-7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26680596%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26680596%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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