(Q38816622)

English

Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation.

scientific article published on 25 November 2015

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

17

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Hong Shen

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Tongtong Liu

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Hao Jiang

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Craig Titsch

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Kristin Taylor

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Hamza Kandoussi

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Xi Qiu

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Cliff Chen

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Sunil Sukrutharaj

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Kathy Kuit

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Gabe Mintier

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Prasad Krishnamurthy

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

R Marcus Fancher

13

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Jianing Zeng

14

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

A David Rodrigues

15

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Punit Marathe

16

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

publication date

25 November 2015

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Drug Metabolism and Disposition

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

44

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

238-249

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Tissue distribution and ontogeny of organic cation transporters in mice

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Effects of tetraalkylammonium compounds with different affinities for organic cation transporters on the pharmacokinetics of metformin

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Pyrimethamine pharmacokinetics and its tissue localization in mice: effect of dose size

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Solute carrier transporter and drug-related nephrotoxicity: the impact of proximal tubule cell models for preclinical research

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Membrane transporters in drug development

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Prediction of fluoroquinolone-induced elevation in serum creatinine levels: a case of drug-endogenous substance interaction involving the inhibition of renal secretion.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Novel pre-clinical methodologies for pharmacokinetic drug-drug interaction studies: spotlight on "humanized" animal models.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Evaluation of the usefulness of breast cancer resistance protein (BCRP) knockout mice and BCRP inhibitor-treated monkeys to estimate the clinical impact of BCRP modulation on the pharmacokinetics of BCRP substrates

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Renal transporters in drug development

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Multidrug and toxin extrusion family SLC47: physiological, pharmacokinetic and toxicokinetic importance of MATE1 and MATE2-K.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Precise comparison of protein localization among OCT, OAT, and MATE in human kidney

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Molecular mechanism of renal tubular secretion of the antimalarial drug chloroquine

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Drug specificity and intestinal membrane localization of human organic cation transporters (OCT).

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Involvement of carnitine/organic cation transporter OCTN1/SLC22A4 in gastrointestinal absorption of metformin.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

A human transporter protein that mediates the final excretion step for toxic organic cations

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Absolute measurement of species differences in sodium taurocholate cotransporting polypeptide (NTCP/Ntcp) and its modulation in cultured hepatocytes.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Clinical pharmacokinetics of metformin

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Evaluation of rosuvastatin as an organic anion transporting polypeptide (OATP) probe substrate: in vitro transport and in vivo disposition in cynomolgus monkeys.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Cynomolgus monkey as a potential model to assess drug interactions involving hepatic organic anion transporting polypeptides: in vitro, in vivo, and in vitro-to-in vivo extrapolation

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Pitavastatin as an in vivo probe for studying hepatic organic anion transporting polypeptide-mediated drug-drug interactions in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Use of in vivo animal models to assess pharmacokinetic drug-drug interactions

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Protective effect of concomitant administration of imatinib on cisplatin-induced nephrotoxicity focusing on renal organic cation transporter OCT2.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A).

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Creatinine transport by basolateral organic cation transporter hOCT2 in the human kidney

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Role of organic cation transporters in the renal handling of therapeutic agents and xenobiotics

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Molecular identification and functional characterization of rabbit MATE1 and MATE2-K.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2).

1 reference

https://api.crossref.org/works/10.1124%2FDMD.115.066852

21 January 2018

Identifiers

10.1124/DMD.115.066852

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

release_jvyyj5p2dvbpxfdeyz5ipp5vq4

1 reference

https://api.fatcat.wiki/v0/release/jvyyj5p2dvbpxfdeyz5ipp5vq4

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26608080%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38816622&oldid=2109297866"