(Q38826536)

15 July 2018

title

Clinical Trial of the Anti-PD-L1 Antibody BMS-936559 in HIV-1 Infected Participants on Suppressive Antiretroviral Therapy (English)

1 reference

15 July 2018

main subject

anti-retroviral agent

0 references

16

Joseph J Eron

1 reference

15 July 2018

Richard A Koup

14

object named as

Richard A Koup

1 reference

15 July 2018

author name string

Cynthia L Gay

1

1 reference

15 July 2018

Ronald J Bosch

2

1 reference

15 July 2018

Justin Ritz

3

1 reference

15 July 2018

Jason M Hataye

4

1 reference

15 July 2018

Evgenia Aga

5

1 reference

15 July 2018

Randall L Tressler

6

1 reference

15 July 2018

Stephen W Mason

7

1 reference

15 July 2018

Carey K Hwang

8

1 reference

15 July 2018

Dennis M Grasela

9

1 reference

15 July 2018

Neelanjana Ray

10

1 reference

15 July 2018

Josh C Cyktor

11

1 reference

15 July 2018

John M Coffin

12

1 reference

15 July 2018

Edward P Acosta

13

1 reference

15 July 2018

John W Mellors

15

1 reference

15 July 2018

AIDS Clinical Trials 5326 Study Team

17

1 reference

15 July 2018

language of work or name

English

0 references

publication date

1 June 2017

1 reference

15 July 2018

Journal of Infectious Diseases

published in

1 reference

15 July 2018

volume

215

1 reference

15 July 2018

issue

11

1 reference

15 July 2018

page(s)

1725-1733

1 reference

15 July 2018

HIV and hypogonadism: a new challenge for young-aged and middle-aged men on effective antiretroviral therapy

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Prevalence of testosterone deficiency in HIV-infected men under antiretroviral therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Programed death-1/programed death-ligand 1 expression in lymph nodes of HIV infected patients: results of a pilot safety study in rhesus macaques using anti-programed death-ligand 1 (Avelumab).

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Immune Checkpoint Inhibitors: Review and Management of Endocrine Adverse Events.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Novel Assays for Measurement of Total Cell-Associated HIV-1 DNA and RNA.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Immune Checkpoint Inhibitors: New Insights and Current Place in Cancer Therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Receptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Immune exhaustion occurs concomitantly with immune activation and decrease in regulatory T cells in viremic chronically HIV-1-infected patients

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Enhancing SIV-specific immunity in vivo by PD-1 blockade

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Viral immune evasion due to persistence of activated T cells without effector function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Improved single-copy assays for quantification of persistent HIV-1 viremia in patients on suppressive antiretroviral therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD-L1 blockade in chronic hepadnaviral infection

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Breakthrough of the year 2013. Cancer immunotherapy

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Human immune deficiency virus (HIV) infection and the hypothalamic pituitary adrenal axis

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5790148

B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression

22 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FINFDIS%2FJIX191

Expression of PD-L1, a marker of disease status, is not reduced by HAART in aviraemic patients

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28431010

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28431010

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/INFDIS/JIX191

1 reference

15 July 2018

release_xatjqc3aqngp5a7wbsphdk3fa4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xatjqc3aqngp5a7wbsphdk3fa4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

5790148

1 reference

15 July 2018

PubMed ID

28431010

1 reference

15 July 2018