(Q38827412)

English

Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition.

scientific article published on October 2015

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26474067%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition (English)

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27 February 2020

Ryan M Sheridan

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27 February 2020

David L Bentley

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27 February 2020

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Nova Fong

1

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27 February 2020

Kristopher Brannan

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27 February 2020

Benjamin Erickson

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27 February 2020

Hyunmin Kim

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27 February 2020

Michael A Cortazar

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27 February 2020

Tram Nguyen

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27 February 2020

Shai Karp

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27 February 2020

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1 October 2015

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27 February 2020

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27 February 2020

60

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27 February 2020

2

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27 February 2020

256-267

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27 February 2020

Widespread Inducible Transcription Downstream of Human Genes

1 reference

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9 September 2017

Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs

1 reference

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9 September 2017

Unraveling the mechanistic features of RNA polymerase II termination by the 5'-3' exoribonuclease Rat1

1 reference

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9 September 2017

The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway

1 reference

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9 September 2017

The Integrator complex controls the termination of transcription at diverse classes of gene targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate.

1 reference

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9 September 2017

Genome-wide mapping of yeast RNA polymerase II termination

1 reference

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9 September 2017

4sUDRB-seq: measuring genomewide transcriptional elongation rates and initiation frequencies within cells

1 reference

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9 September 2017

Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications

1 reference

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9 September 2017

Mammalian 5'-capped microRNA precursors that generate a single microRNA.

1 reference

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9 September 2017

A bacterial-like mechanism for transcription termination by the Sen1p helicase in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Dismantling promoter-driven RNA polymerase II transcription complexes in vitro by the termination factor Rat1.

1 reference

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9 September 2017

Definition of RNA polymerase II CoTC terminator elements in the human genome.

1 reference

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9 September 2017

Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

How to stop: the mysterious links among RNA polymerase II occupancy 3' of genes, mRNA 3' processing and termination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

RNA polymerase II pausing downstream of core histone genes is different from genes producing polyadenylated transcripts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

1 reference

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9 September 2017

Pre-mRNA splicing is a determinant of histone H3K36 methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Real-time observation of transcription initiation and elongation on an endogenous yeast gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Unravelling the means to an end: RNA polymerase II transcription termination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Coupled 5′ Nucleotide Recognition and Processivity in Xrn1-Mediated mRNA Decay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

An unexpected ending: noncanonical 3' end processing mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Coupled RNA processing and transcription of intergenic primary microRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

A novel tandem reporter quantifies RNA polymerase II termination in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Transcription termination by nuclear RNA polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Primary microRNA transcripts are processed co-transcriptionally.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3' end RNA polyadenylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Molecular dissection of mammalian RNA polymerase II transcriptional termination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Nucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism

1 reference

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9 September 2017

Genome-wide distribution of yeast RNA polymerase II and its control by Sen1 helicase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Pause sites promote transcriptional termination of mammalian RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

The role of Rat1 in coupling mRNA 3'-end processing to transcription termination: implications for a unified allosteric-torpedo model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

E Pluribus Unum: 3' end formation of polyadenylated mRNAs, histone mRNAs, and U snRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Symplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Dynamic association of capping enzymes with transcribing RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Termination efficiency at rho-dependent terminators depends on kinetic coupling between RNA polymerase and rho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

9 September 2017

Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

14 September 2017

Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

14 September 2017

Human snRNA genes use polyadenylation factors to promote efficient transcription termination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

17 June 2018

Kinetic competition between RNA Polymerase II and Sen1-dependent transcription termination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

17 June 2018

Dynamic transitions in RNA polymerase II density profiles during transcription termination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

17 June 2018

mRNA decapping factors and the exonuclease Xrn2 function in widespread premature termination of RNA polymerase II transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

17 June 2018

Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae.

1 reference

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17 June 2018

Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3' end processing in the human alpha 2 globin gene

1 reference

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17 June 2018

Tumor progression in four mammary epithelial cell lines derived from the same patient

1 reference

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17 June 2018

Poly(A) Signal-Dependent Transcription Termination Occurs through a Conformational Change Mechanism that Does Not Require Cleavage at the Poly(A) Site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

22 August 2018

The RNA exosome promotes transcription termination of backtracked RNA polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

22 August 2018

Pcf11 is a termination factor in Drosophila that dismantles the elongation complex by bridging the CTD of RNA polymerase II to the nascent transcript

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

22 August 2018

Analysis of polymerase II elongation complexes by native gel electrophoresis. Evidence for a novel carboxyl-terminal domain-mediated termination mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

22 August 2018

Coupling termination of transcription to messenger RNA maturation in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654110

22 August 2018

The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/26474067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/26474067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLCEL.2015.09.026

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26474067%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26474067%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26474067%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

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