(Q38845236)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Tracey M Gloster

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Wesley F Zandberg

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Julia E Heinonen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

David L Shen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Lehua Deng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

publication date

23 January 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

174-181

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

20 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3202988/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/nchembio.520

0 references

cites work

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Enzymatic route to preparative-scale synthesis of UDP-GlcNAc/GalNAc, their analogues and GDP-fucose

9 September 2017

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O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death.

9 September 2017

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Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc).

9 September 2017

1 reference

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Chemical approaches to perturb, profile, and perceive glycans

9 September 2017

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Thiasugars: potential glycosidase inhibitors.

9 September 2017

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A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

9 September 2017

1 reference

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Non-canonical glycosyltransferase modulates post-hypoxic cardiac myocyte death and mitochondrial permeability transition

9 September 2017

1 reference

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Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation

9 September 2017

1 reference

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Glycosyltransferases: structures, functions, and mechanisms

9 September 2017

1 reference

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Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

9 September 2017

1 reference

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Increased O-GlcNAc levels during reperfusion lead to improved functional recovery and reduced calpain proteolysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics

9 September 2017

1 reference

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Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins

9 September 2017

1 reference

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Structure and mechanism of a bacterial beta-glucosaminidase having O-GlcNAcase activity

9 September 2017

1 reference

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O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease

9 September 2017

1 reference

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Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability

9 September 2017

1 reference

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Glycan-dependent leukocyte adhesion and recruitment in inflammation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

A chemical approach for identifying O-GlcNAc-modified proteins in cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

The Hexapeptide inhibitor of Galbeta 1,3GalNAc-specific alpha 2,3-sialyltransferase as a generic inhibitor of sialyltransferases

9 September 2017

1 reference

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Biochemical engineering of the N-acyl side chain of sialic acid: biological implications

9 September 2017

1 reference

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Functional cloning and mutational analysis of the human cDNA for phosphoacetylglucosamine mutase: identification of the amino acid residues essential for the catalysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Molecular cloning and characterization of murine and human N-acetylglucosamine kinase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Cell surface engineering by a modified Staudinger reaction

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Suppression of tumor growth and metastasis in Mgat5-deficient mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Dynamic O-GlcNAcylation of the small heat shock protein alpha B-crystallin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis.

9 September 2017

1 reference

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Analysis of nuclear pore protein p62 glycosylation

9 September 2017

1 reference

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Disaccharide uptake and priming in animal cells: inhibition of sialyl Lewis X by acetylated Gal beta 1-->4GlcNAc beta-O-naphthalenemethanol

9 September 2017

1 reference

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Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Alloxan: history and mechanism of action

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Decreased UDP-GlcNAc levels abrogate proliferation control in EMeg32-deficient cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Perturbations in O-linked beta-N-acetylglucosamine protein modification cause severe defects in mitotic progression and cytokinesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Probing synergy between two catalytic strategies in the glycoside hydrolase O-GlcNAcase using multiple linear free energy relationships

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Discovery of O-GlcNAc transferase inhibitors

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Two-step enzymatic synthesis of UDP-N-acetylgalactosamine

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Characterization of the cellular uptake and metabolic conversion of acetylated N-acetylmannosamine (ManNAc) analogues to sialic acids

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

Synthesis of GDP-5-thiosugars and their use as glycosyl donor substrates for glycosyltransferases

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

The mechanism of inhibition of glycosylphosphatidylinositol anchor biosynthesis in Trypanosoma brucei by mannosamine

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3202988

The effect of tunicamycin, an inhibitor of protein glycosylation, on embryonic development in the sea urchin

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21258330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.520

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21258330%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference