(Q38870844)

7 September 2017

High-throughput decoding of antitrypanosomal drug efficacy and resistance (English)

1 reference

zinc-binding phosphatase, putative

7 September 2017

1 reference

5 February 2019

trypanothione synthetase

1 reference

5 February 2019

adenosine transporter 2

1 reference

5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

adenosine transporter 2

1 reference

5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

1 reference

clathrin coat assembly protein ap19, putative

5 February 2019

1 reference

endosomal integral membrane protein, putative

5 February 2019

1 reference

gamma-adaptin 1, putative

5 February 2019

1 reference

protein phosphatase 2C, putative

5 February 2019

1 reference

5 February 2019

adenosine transporter 1

1 reference

5 February 2019

1 reference

75 kDa invariant surface glycoprotein

5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

1 reference

5 February 2019

1 reference

lysosomal/endosomal membrane protein p67

5 February 2019

1 reference

UDP-Gal or UDP-GlcNAc-dependent glycosyltransferase, putative

5 February 2019

1 reference

purine nucleoside transporter

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

cysteine peptidase, Clan CA, family C1, Cathepsin L-like

5 February 2019

1 reference

Uncharacterised ACR, YagE family COG1723, putative

5 February 2019

1 reference

S-adenosylmethionine decarboxylase

5 February 2019

1 reference

S-adenosylmethionine decarboxylase

5 February 2019

1 reference

5 February 2019

Mu-adaptin 1, putative

1 reference

PX domain containing protein, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

glucosamine-fructose-6-phosphate aminotransferase, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

amino acid permease 24

1 reference

mitogen-activated protein kinase kinase 4, putative

6 February 2019

1 reference

6 February 2019

aquaporin 2, putative

1 reference

amino acid transporter AATP5

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

purine nucleoside transporter

6 February 2019

1 reference

riboflavin kinase, putative

6 February 2019

1 reference

Autophagy-related protein 24

6 February 2019

1 reference

cysteine peptidase, Clan CA, family C19, putative

6 February 2019

1 reference

calcium motive p-type ATPase, putative

6 February 2019

1 reference

serine peptidase, Clan SC, Family S10

6 February 2019

1 reference

serine peptidase, Clan SC, Family S10

6 February 2019

1 reference

serine peptidase, Clan SC, Family S10

6 February 2019

1 reference

Temperature dependent protein affecting M2 dsRNA replication, putative

6 February 2019

1 reference

STE/STE11 serine/threonine-protein kinase, putative

6 February 2019

1 reference

The ARF-like 2 binding protein BART, putative

6 February 2019

1 reference

adaptin complex 1 subunit, putative

6 February 2019

1 reference

Mitoribosomal SSU assembly factor 29

6 February 2019

1 reference

6 February 2019

ABC1 protein, putative

1 reference

mitogen-activated protein kinase 11, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

P-type H+-ATPase, putative

1 reference

P-type H+-ATPase, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

C-terminal motor kinesin, putative

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

1 reference

Uncharacterised ACR, YagE family COG1723, putative

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

ubiquitin carboxyl-terminal hydrolase, putative

1 reference

mitochondrial carrier protein

6 February 2019

1 reference

6 February 2019

1 reference

6 February 2019

0 references

aquaporin 2, putative

0 references

aquaporin 2, putative

0 references

Nicola Baker

3

0 references

Lucy Glover

Lucy Glover

4

0 references

Alejandro Sanchez-Flores

Alejandro Sanchez-Flores

5

0 references

Sam Alsford

Sam Alsford

1

0 references

Mark C. Field

Mark C Field

8

0 references

David A. Horn

David Horn

10

0 references

Matthew Berriman

9

Matthew Berriman

1 reference

7 September 2017

Sabine Eckert

2

1 reference

7 September 2017

Ka Fai Leung

6

1 reference

7 September 2017

Daniel J Turner

7

1 reference

7 September 2017

language of work or name

English

0 references

publication date

25 January 2012

1 reference

7 September 2017

1 reference

7 September 2017

482

1 reference

7 September 2017

7384

1 reference

7 September 2017

232-236

1 reference

Ubiquitylation and developmental regulation of invariant surface protein expression in trypanosomes

7 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

A molecular mechanism for eflornithine resistance in African trypanosomes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

The development of drugs for treatment of sleeping sickness: a historical review

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

The burden of human African trypanosomiasis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Single-locus targeting constructs for reliable regulated RNAi and transgene expression in Trypanosoma brucei

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Tagging a T. brucei RRNA locus improves stable transfection efficiency and circumvents inducible expression position effects

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

The Genome of the African Trypanosome Trypanosoma brucei

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Invariant surface proteins in bloodstream forms of Trypanosoma brucei.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Chemotherapy of human African trypanosomiasis: current and future prospects

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

SSAHA: a fast search method for large DNA databases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Arsenical-resistant trypanosomes lack an unusual adenosine transporter

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Organization of two invariant surface glycoproteins in the surface coat of Trypanosoma brucei.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Trypanothione is the primary target for arsenical drugs against African trypanosomes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

The mitochondrion is a site of trypanocidal action of the aromatic diamidine DB75 in bloodstream forms of Trypanosoma brucei

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Molecular characterization of Trypanosoma brucei P-type H+-ATPases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

A nucleoside transporter from Trypanosoma brucei involved in drug resistance.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

The treatment of human African trypanosomiasis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

The LAMP-like protein p67 plays an essential role in the lysosome of African trypanosomes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Activation of endocytosis as an adaptation to the mammalian host by trypanosomes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Characterization of tGLP-1, a Golgi and lysosome-associated, transmembrane glycoprotein of African trypanosomes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Processing and transport of a lysosomal membrane glycoprotein is developmentally regulated in African trypanosomes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Uptake of the trypanocidal drug suramin by bloodstream forms of Trypanosoma brucei and its effect on respiration and growth rate in vivo

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Address in Pathology, ON CHEMIOTHERAPY: Delivered before the Seventeenth International Congress of Medicine

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineage

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Dileucine signal-dependent and AP-1-independent targeting of a lysosomal glycoprotein in Trypanosoma brucei

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Ever-increasing complexities of diamidine and arsenical crossresistance in African trypanosomes

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

Synergistic and additive killing by antimicrobial factors found in human airway surface liquid

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303116

The uptake of the trypanocidal drug suramin in combination with low-density lipoproteins by Trypanosoma brucei and its possible mode of action

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22278056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22278056

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10771

1 reference

Dimensions Publication ID

7 September 2017

0 references

1 reference

7 September 2017

PubMed publication ID

22278056

1 reference