(Q38871309)

7 September 2017

title

Spatial genomic heterogeneity within localized, multifocal prostate cancer (English)

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7 September 2017

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62

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7 September 2017

Richard de Borja

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James Hawley

James Hawley

46

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Andrew McPherson

Andrew McPherson

9

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Nicholas J Harding

Nicholas J Harding

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Julie Livingstone

Julie Livingstone

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Timothy Beck

Timothy A Beck

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Francis Nguyen

Francis Nguyen

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Dominique Trudel

Dominique Trudel

5

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Alejandro Berlin

Alejandro Berlin

34

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Paul C. Boutros

Paul C Boutros

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John McPherson

John D McPherson

63

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Robert G. Bristow

Robert G Bristow

Theodorus H Van der Kwast

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Theodorus van der Kwast

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Rosalind Eeles

Rosalind Eeles

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Lincoln Stein

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Lincoln D Stein

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Lambin P

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David Neal

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2

Michael Fraser

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37

Fouad Yousif

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Lee Timms

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18

Taryne Chong

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Emilie Lalonde

6

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Alice Meng

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Pablo H Hennings-Yeomans

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Veronica Y Sabelnykova

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Amin Zia

11

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Natalie S Fox

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Yu-Jia Shiah

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7 September 2017

Jianxin Wang

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Cherry L Have

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Michelle Sam

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Jeremy Johns

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Nicholas Buchner

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Ada Wong

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John D Watson

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Trent T Simmons

25

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Christine P'ng

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Gaetano Zafarana

27

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Xuemei Luo

29

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7 September 2017

Kenneth C Chu

30

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Stephenie D Prokopec

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Jenna Sykes

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Alan Dal Pra

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Andrew Brown

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7 September 2017

Michelle A Chan-Seng-Yue

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Robert E Denroche

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Lauren C Chong

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Gregory M Chen

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Esther Jung

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Clement Fung

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Maud H W Starmans

43

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Hanbo Chen

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Shaylan K Govind

45

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7 September 2017

Alister D'Costa

47

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7 September 2017

Melania Pintilie

48

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Daryl Waggott

49

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7 September 2017

Faraz Hach

50

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7 September 2017

Lakshmi B Muthuswamy

52

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7 September 2017

Colin Cooper

53

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Bernard Tetu

56

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Cenk Sahinalp

57

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Neil Fleshner

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Sohrab P Shah

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Colin C Collins

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7 September 2017

language of work or name

English

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publication date

25 May 2015

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7 September 2017

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7 September 2017

volume

47

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7 September 2017

issue

7

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7 September 2017

page(s)

736-745

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Exome sequencing of prostate cancer supports the hypothesis of independent tumour origins

7 September 2017

cites work

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Architecture of the human regulatory network derived from ENCODE data

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12 December 2020

Histological grade heterogeneity in multifocal prostate cancer. Biological and clinical implications

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12 December 2020

The genomic complexity of primary human prostate cancer

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12 December 2020

Screening for prostate cancer: systematic review and meta-analysis of randomised controlled trials

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12 December 2020

Genomic profiling reveals alternative genetic pathways of prostate tumorigenesis

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12 December 2020

NCCN clinical practice guidelines in oncology: prostate cancer

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12 December 2020

Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors

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12 December 2020

Allelic loss of the loci containing the androgen synthesis gene, StAR, is prognostic for relapse in intermediate-risk prostate cancer

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12 December 2020

Cancer-specific mortality after surgery or radiation for patients with clinically localized prostate cancer managed during the prostate-specific antigen era.

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12 December 2020

Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer

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12 December 2020

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

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12 December 2020

Validating the interval to biochemical failure for the identification of potentially lethal prostate cancer

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12 December 2020

PIK3CA mutation H1047R is associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trials

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12 December 2020

Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

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12 December 2020

nFuse: discovery of complex genomic rearrangements in cancer using high-throughput sequencing

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12 December 2020

CREST maps somatic structural variation in cancer genomes with base-pair resolution.

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12 December 2020

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

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12 December 2020

High-resolution array CGH identifies novel regions of genomic alteration in intermediate-risk prostate cancer

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12 December 2020

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

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12 December 2020

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

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12 December 2020

Database resources of the National Center for Biotechnology Information

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12 December 2020

Biomarkers of response to Akt inhibitor MK-2206 in breast cancer

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12 December 2020

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

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12 December 2020

The Sequence Alignment/Map format and SAMtools

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12 December 2020

Bioconductor: open software development for computational biology and bioinformatics

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12 December 2020

Fast and accurate long-read alignment with Burrows-Wheeler transform

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12 December 2020

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

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12 December 2020

GENCODE: the reference human genome annotation for The ENCODE Project

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12 December 2020

mRNA expression signature of Gleason grade predicts lethal prostate cancer

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12 December 2020

The landscape of somatic copy-number alteration across human cancers

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12 December 2020

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

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12 December 2020

The mutational landscape of lethal castration-resistant prostate cancer

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12 December 2020

Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy

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12 December 2020

The genetic landscape of high-risk neuroblastoma

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12 December 2020

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

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12 December 2020

BEDTools: a flexible suite of utilities for comparing genomic features

1 reference

12 December 2020

Multiple cancers in the prostate. Morphologic features of clinically recognized versus incidental tumors

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12 December 2020

A framework for variation discovery and genotyping using next-generation DNA sequencing data

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12 December 2020

Integrative genomic profiling of human prostate cancer

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12 December 2020

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

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12 December 2020

High frequency of mutations of the PIK3CA gene in human cancers

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12 December 2020

Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

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12 December 2020

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

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12 December 2020

Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies

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12 December 2020

A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries

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12 December 2020

Gene amplifications associated with the development of hormone-resistant prostate cancer

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12 December 2020

The mitochondrial and autosomal mutation landscapes of prostate cancer

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12 December 2020

Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study

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12 December 2020

Punctuated evolution of prostate cancer genomes

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12 December 2020

Negative autoregulation of c-myc transcription

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12 December 2020

The duplicated genes database: identification and functional annotation of co-localised duplicated genes across genomes

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12 December 2020

RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings

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12 December 2020

Tabix: fast retrieval of sequence features from generic TAB-delimited files

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12 December 2020

Epigenetic markers of prostate cancer in plasma circulating DNA.

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12 December 2020

qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles

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12 December 2020

Detecting false-positive signals in exome sequencing

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12 December 2020

NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy

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12 December 2020

VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R

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12 December 2020

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

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12 December 2020

SeqWare Query Engine: storing and searching sequence data in the cloud

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12 December 2020

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

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12 December 2020

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

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12 December 2020

Summaries of Affymetrix GeneChip probe level data

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12 December 2020

Optimal treatment of intermediate-risk prostate carcinoma with radiotherapy: clinical and translational issues

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12 December 2020

Identifiers

DOI

10.1038/NG.3315

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7 September 2017

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