(Q38872538)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25997032%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Designing the furin-cleavable linker in recombinant immunotoxins based on Pseudomonas exotoxin A (English)

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8 March 2020

1

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8 March 2020

author name string

Martin Skarzynski

2

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8 March 2020

Jamy A Therres

3

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8 March 2020

Joshua R Ostovitz

4

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8 March 2020

Hong Zhou

5

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8 March 2020

Robert J Kreitman

6

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8 March 2020

Ira Pastan

7

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8 March 2020

publication date

3 June 2015

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8 March 2020

published in

Bioconjugate Chemistry

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8 March 2020

volume

26

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8 March 2020

issue

6

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8 March 2020

page(s)

1120-1128

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CD22 is a recycling receptor that can shuttle cargo between the cell surface and endosomal compartments of B cells

8 March 2020

cites work

1 reference

12 December 2020

Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes

1 reference

12 December 2020

A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.

1 reference

12 December 2020

Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

12 December 2020

Phase I trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P.

1 reference

12 December 2020

A recombinant immunotoxin containing a disulfide-stabilized Fv fragment

1 reference

12 December 2020

Recombinant immunotoxins in the treatment of cancer

1 reference

12 December 2020

NIH Image to ImageJ: 25 years of image analysis

1 reference

12 December 2020

A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer

1 reference

12 December 2020

Retracted: A Femtomol Range FRET Biosensor Reports Exceedingly Low Levels of Cell Surface Furin: Implications for the Processing of Anthrax Protective Antigen

1 reference

12 December 2020

Major Cancer Regressions in Mesothelioma After Treatment with an Anti-Mesothelin Immunotoxin and Immune Suppression

1 reference

12 December 2020

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.

1 reference

12 December 2020

Improving antibody affinity by mimicking somatic hypermutation in vitro

1 reference

12 December 2020

Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.

1 reference

12 December 2020

Prediction of proprotein convertase cleavage sites

1 reference

12 December 2020

A study of human furin specificity using synthetic peptides derived from natural substrates, and effects of potassium ions

1 reference

12 December 2020

Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia

1 reference

12 December 2020

A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicity

1 reference

12 December 2020

Substrate cleavage analysis of furin and related proprotein convertases. A comparative study

1 reference

12 December 2020

Mesothelin: a new target for immunotherapy

1 reference

12 December 2020

Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers

1 reference

12 December 2020

A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.

1 reference

12 December 2020

GPI-anchor remodeling: potential functions of GPI-anchors in intracellular trafficking and membrane dynamics

1 reference

12 December 2020

An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies

1 reference

12 December 2020

Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol

1 reference

12 December 2020

Improved cytotoxic activity toward cell lines and fresh leukemia cells of a mutant anti-CD22 immunotoxin obtained by antibody phage display.

1 reference

12 December 2020

Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv.

1 reference

12 December 2020

Reduction of furin-nicked Pseudomonas exotoxin A: an unfolding story

1 reference

12 December 2020

Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion.

1 reference

12 December 2020

Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL.

1 reference

12 December 2020

Furin-mediated cleavage of Pseudomonas exotoxin-derived chimeric toxins.

1 reference

12 December 2020

Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases

1 reference

12 December 2020

Induction of caspase-dependent programmed cell death in B-cell chronic lymphocytic leukemia by anti-CD22 immunotoxins

1 reference

12 December 2020

Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary

1 reference

12 December 2020

Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes

1 reference

12 December 2020

Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotox

1 reference

12 December 2020

FurinDB: A database of 20-residue furin cleavage site motifs, substrates and their associated drugs

1 reference

12 December 2020

CAT-8015: a second-generation pseudomonas exotoxin A-based immunotherapy targeting CD22-expressing hematologic malignancies

1 reference

12 December 2020

10.1021/ACS.BIOCONJCHEM.5B00190

Identifiers

DOI

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release_ascwjiobj5bzhdvfzgi5npogxi

8 March 2020

Fatcat ID

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