(Q38880070)

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Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor

scientific article published on May 2015

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scholarly article

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Europe PubMed Central

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7 September 2017

Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor (English)

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7 September 2017

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based on heuristic

inferred from title

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10 June 2020

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10 June 2020

Lecia V Sequist

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10 June 2020

Mari Mino-Kenudson

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Mari Mino-Kenudson

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10 June 2020

Dora Dias-Santagata

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10 June 2020

Jeffrey A Engelman

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Jeffrey A Engelman

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10 June 2020

19

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A John Iafrate

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10 June 2020

author name string

Zofia Piotrowska

1

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10 June 2020

Matthew J Niederst

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10 June 2020

Chris A Karlovich

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10 June 2020

Heather A Wakelee

4

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10 June 2020

Joel W Neal

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10 June 2020

Linnea Fulton

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10 June 2020

Elizabeth L Lockerman

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10 June 2020

Anuj Kalsy

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10 June 2020

Subba Digumarthy

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10 June 2020

Alona Muzikansky

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10 June 2020

Mitch Raponi

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10 June 2020

Angel R Garcia

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10 June 2020

Hillary E Mulvey

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10 June 2020

Richard H DiCecca

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10 June 2020

Alice T Shaw

20

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10 June 2020

Andrew R Allen

21

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10 June 2020

publication date

1 May 2015

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7 September 2017

Cancer Discovery

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10 June 2020

5

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10 June 2020

7

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10 June 2020

713-722

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10 June 2020

Rociletinib in EGFR-mutated non-small-cell lung cancer

1 reference

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9 September 2017

AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497836

9 September 2017

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497836

9 September 2017

Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497836

9 September 2017

Patient-derived models of acquired resistance can identify effective drug combinations for cancer.

1 reference

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9 September 2017

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

1 reference

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9 September 2017

Emerging paradigms in the development of resistance to tyrosine kinase inhibitors in lung cancer

1 reference

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9 September 2017

Bypass mechanisms of resistance to receptor tyrosine kinase inhibition in lung cancer

1 reference

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9 September 2017

Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers

1 reference

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9 September 2017

Genomic landscape of non-small cell lung cancer in smokers and never-smokers

1 reference

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9 September 2017

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

1 reference

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9 September 2017

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

1 reference

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9 September 2017

ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells

1 reference

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9 September 2017

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

1 reference

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9 September 2017

Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497836

9 September 2017

New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

1 reference

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9 September 2017

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497836

9 September 2017

Detection and quantification of mutations in the plasma of patients with colorectal tumors

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9 September 2017

Comparison of the EGFR resistance mutation profiles generated by EGFR-targeted tyrosine kinase inhibitors and the impact of drug combinations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497836

14 September 2017

Anchored multiplex PCR for targeted next-generation sequencing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497836

22 August 2018

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4497836

22 August 2018

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

1 reference

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22 August 2018

Reciprocal and complementary role of MET amplification and EGFR T790M mutation in acquired resistance to kinase inhibitors in lung cancer

1 reference

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22 August 2018

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

1 reference

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22 August 2018

First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations

1 reference

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Biomarker Analyses and Final Overall Survival Results From a Phase III, Randomized, Open-Label, First-Line Study of Gefitinib Versus Carboplatin/Paclitaxel in Clinically Selected Patients With Advanced Non–Small-Cell Lung Cancer in Asia (IPASS)

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2 December 2018

Identifiers

10.1158/2159-8290.CD-15-0399

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Europe PubMed Central

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10 June 2020

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Europe PubMed Central

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10 June 2020

PubMed publication ID

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Europe PubMed Central

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10 June 2020

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