(Q38881975)

7 September 2017

MicroRNA-17-5p activates hepatic stellate cells through targeting of Smad7. (English)

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7 September 2017

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Fujun Yu

1

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7 September 2017

Yong Guo

2

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7 September 2017

Bicheng Chen

3

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7 September 2017

Peihong Dong

4

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7 September 2017

Jianjian Zheng

5

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7 September 2017

27 April 2015

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7 September 2017

Laboratory Investigation

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7 September 2017

95

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7 September 2017

7

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7 September 2017

781-789

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https://scigraph.springernature.com/pub.10.1038/labinvest.2015.58

7 September 2017

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cites work

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MicroRNA-21 activates hepatic stellate cells via PTEN/Akt signaling

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Evolving challenges in hepatic fibrosis

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Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver

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MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death

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MiR-21 simultaneously regulates ERK1 signaling in HSC activation and hepatocyte EMT in hepatic fibrosis

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Suppression of hepatic stellate cell activation by microRNA-29b.

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Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis

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mir-17-92, a cluster of miRNAs in the midst of the cancer network

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miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway

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Inhibition by curcumin of multiple sites of the transforming growth factor-beta1 signalling pathway ameliorates the progression of liver fibrosis induced by carbon tetrachloride in rats

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MicroRNA-155 attenuates activation of hepatic stellate cell by simultaneously preventing EMT process and ERK1 signalling pathway.

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Analyzing real-time PCR data by the comparative C(T) method

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MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway

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Activation of peroxisome proliferator-activated receptor-gamma by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells

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Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

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The potential of microRNAs in liver fibrosis

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Repression of Smad7 mediated by DNMT1 determines hepatic stellate cell activation and liver fibrosis in rats

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

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Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage

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MicroRNA-216a/217-induced epithelial-mesenchymal transition targets PTEN and SMAD7 to promote drug resistance and recurrence of liver cancer

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Histone deacetylase 4 is required for TGFbeta1-induced myofibroblastic differentiation

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Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.

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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

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MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis.

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The microRNA spectrum in 12 body fluids

21 January 2018

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Serum microRNA-122 predicts survival in patients with liver cirrhosis

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miR-33a levels in hepatic and serum after chronic HBV-induced fibrosis.

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Mature miR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7 and vimentin in different signal pathways

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12 December 2020

Serum microRNAs are promising novel biomarkers for diffuse large B cell lymphoma

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12 December 2020

High expression of serum miR-17-5p associated with poor prognosis in patients with hepatocellular carcinoma

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12 December 2020

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12 December 2020

Liver fibrosis: from mechanisms to treatment

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12 December 2020

Transforming growth factor beta signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts. TGFbeta signal transduction during transdifferentiation of hepatic

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12 December 2020

10.1038/LABINVEST.2015.58

Identifiers

DOI

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Dimensions Publication ID

7 September 2017

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