(Q38888514)

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Discovery of a Promiscuous Non-Heme Iron Halogenase in Ambiguine Alkaloid Biogenesis: Implication for an Evolvable Enzyme Family for Late-Stage Halogenation of Aliphatic Carbons in Small Molecules

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Europe PubMed Central

PubMed publication ID

7 September 2017

Discovery of a Promiscuous Non-Heme Iron Halogenase in Ambiguine Alkaloid Biogenesis: Implication for an Evolvable Enzyme Family for Late-Stage Halogenation of Aliphatic Carbons in Small Molecules (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

12-epi-fischerindole G

1 reference

ChEBI release 2020-05-28

Matthew L. Hillwig

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Matthew L Hillwig

1

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author name string

Qin Zhu

2

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Kuljira Ittiamornkul

3

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Xinyu Liu

4

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

language of work or name

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publication date

30 March 2016

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Europe PubMed Central

PubMed publication ID

7 September 2017

Angewandte Chemie International Edition

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55

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Europe PubMed Central

PubMed publication ID

7 September 2017

19

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

5780-5784

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Stereoselective Halogenation in Natural Product Synthesis

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Biosynthesis of (-)-(1S,2R)-allocoronamic acyl thioester by an Fe(II)-dependent halogenase and a cyclopropane-forming flavoprotein

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Metamorphic enzyme assembly in polyketide diversification

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Biosynthetic chlorination of the piperazate residue in kutzneride biosynthesis by KthP.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Substrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Identification and characterization of a welwitindolinone alkaloid biosynthetic gene cluster in the stigonematalean Cyanobacterium Hapalosiphon welwitschii.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

A new family of iron-dependent halogenases acts on freestanding substrates.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Unified biogenesis of ambiguine, fischerindole, hapalindole and welwitindolinone: identification of a monogeranylated indolenine as a cryptic common biosynthetic intermediate by an unusual magnesium-dependent aromatic prenyltransferase

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Halogenase Engineering for the Generation of New Natural Product Analogues

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Antimicrobial ambiguines from the cyanobacterium Fischerella sp. collected in Israel

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Manganese Porphyrins Catalyze Selective C−H Bond Halogenations

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Site-Selective Aliphatic C-H Chlorination Using N-Chloroamides Enables a Synthesis of Chlorolissoclimide

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201601447

21 January 2018

Identifiers

10.1002/ANIE.201601447

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

release_okm7ofxalrgdngit5g7b5omlwe

1 reference

https://api.fatcat.wiki/v0/release/okm7ofxalrgdngit5g7b5omlwe

24 November 2022

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

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