(Q38891812)

English

CRLX101, an investigational camptothecin-containing nanoparticle-drug conjugate, targets cancer stem cells and impedes resistance to antiangiogenic therapy in mouse models of breast cancer.

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

CRLX101, an investigational camptothecin-containing nanoparticle-drug conjugate, targets cancer stem cells and impedes resistance to antiangiogenic therapy in mouse models of breast cancer (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

0 references

angiogenesis inhibitor

1 reference

based on heuristic

inferred from title

neoplastic stem cells

1 reference

based on heuristic

inferred from title

author name string

Sarah J Conley

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Trenton L Baker

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Rebecca L Theisen

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Douglas Lazarus

5

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Christian G Peters

6

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Europe PubMed Central

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4 March 2020

Shawn G Clouthier

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Scott Eliasof

8

1 reference

Europe PubMed Central

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4 March 2020

language of work or name

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publication date

2 April 2015

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Breast Cancer Research and Treatment

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

150

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4 March 2020

3

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4 March 2020

559-567

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Europe PubMed Central

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4 March 2020

https://scigraph.springernature.com/pub.10.1007/s10549-015-3349-8

0 references

Angiogenesis: an organizing principle for drug discovery?

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Targeting hypoxia in cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Cancer stem cells, hypoxia and metastasis

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Cancer stem cells at the crossroads of current cancer therapy failures--radiation oncology perspective

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Schedule-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation, angiogenesis, and tumor growth by topotecan in U251-HRE glioblastoma xenografts

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Modulation of camptothecin analogs in the treatment of cancer: a review

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Preclinical to clinical development of the novel camptothecin nanopharmaceutical CRLX101.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Bridging the gap between cytotoxic and biologic therapy with metronomic topotecan and pazopanib in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10549-015-3349-8

21 January 2018

Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells

1 reference

12 January 2024

https://opencitations.net/index/api/v1/citations/10.1073/PNAS.1421438111

Identifiers

10.1007/S10549-015-3349-8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25833208%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

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