(Q38916519)

7 September 2017

title

Phosphorylation and turnover of paxillin in focal contacts is controlled by force and defines the dynamic state of the adhesion site (English)

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7 September 2017

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12

Götz von Wichert

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Thomas Seufferlein

7

object named as

Thomas Seufferlein

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Denis Krndija

5

object named as

Denis Krndija

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Anita Ignatius

9

object named as

Anita Ignatius

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7 September 2017

6

Guido Adler

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7 September 2017

Ruifang Qin

1

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7 September 2017

Heidrun Schmid

2

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7 September 2017

Christin Münzberg

3

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7 September 2017

Ulrike Maass

4

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7 September 2017

Astrid Liedert

8

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7 September 2017

Franz Oswald

10

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7 September 2017

Tim Eiseler

11

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7 September 2017

publication date

7 February 2015

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7 September 2017

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7 September 2017

volume

72

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7 September 2017

issue

2

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7 September 2017

page(s)

101-112

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Phosphorylation of paxillin LD4 destabilizes helix formation and inhibits binding to focal adhesion kinase.

7 September 2017

cites work

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Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner

21 January 2018

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Vinculin tension distributions of individual stress fibers within cell-matrix adhesions

21 January 2018

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Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages

21 January 2018

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Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA

21 January 2018

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Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.

21 January 2018

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α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation.

21 January 2018

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Environmental sensing through focal adhesions

21 January 2018

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Opening the floodgates: proteomics and the integrin adhesome

21 January 2018

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Vinculin-p130Cas interaction is critical for focal adhesion dynamics and mechano-transduction

21 January 2018

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Integrin signalling at a glance

21 January 2018

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Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells

21 January 2018

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Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow.

21 January 2018

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Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells.

21 January 2018

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Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment

21 January 2018

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The role of vinculin in the regulation of the mechanical properties of cells

21 January 2018

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Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

21 January 2018

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Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration

21 January 2018

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Finding the weakest link: exploring integrin-mediated mechanical molecular pathways

21 January 2018

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Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

21 January 2018

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Mechanosensitivity and compositional dynamics of cell-matrix adhesions

21 January 2018

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United we stand: integrating the actin cytoskeleton and cell-matrix adhesions in cellular mechanotransduction.

21 January 2018

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Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth.

21 January 2018

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Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration

21 January 2018

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Activation of c-Src and Fyn kinases by protein-tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization

21 January 2018

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Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids

21 January 2018

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Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2

21 January 2018

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RPTP-alpha acts as a transducer of mechanical force on alphav/beta3-integrin-cytoskeleton linkages

21 January 2018

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Focal adhesion kinase mediates defects in the force-dependent reinforcement of initial integrin-cytoskeleton linkages in metastatic colon cancer cell lines

21 January 2018

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EosFP, a fluorescent marker protein with UV-inducible green-to-red fluorescence conversion

21 January 2018

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Actomyosin-generated tension controls the molecular kinetics of focal adhesions.

21 January 2018

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Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

21 January 2018

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Polarized downregulation of the paxillin-p130CAS-Rac1 pathway induced by shear flow

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/CM.21209

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7 September 2017

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