(Q38919135)

7 September 2017

title

The acinar regulator Gata6 suppresses KrasG12V-driven pancreatic tumorigenesis in mice (English)

1 reference

7 September 2017

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Carmen Guerra

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Francisco X Real

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Francesc Madriles

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Marta Cañamero

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Enrique Carrillo-de Santa Pau

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Natalia Del Pozo

5

1 reference

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31 May 2020

language of work or name

English

0 references

publication date

16 January 2015

1 reference

7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

65

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

476-486

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Pancreatitis is a risk factor for pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Pancreatic ductal adenocarcinoma and acinar cells: a matter of differentiation and development?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Further extension of mammalian GATA-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

GATA4 and GATA6 control mouse pancreas organogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Pepsinogen C: a type 2 cell-specific protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

A novel gastrokine, Gkn3, marks gastric atrophy and shows evidence of adaptive gene loss in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Cloning and expression of the mRNA of human galectin-4, an S-type lectin down-regulated in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Expression and localization of epithelial aquaporins in the adult human lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

A migration signature and plasma biomarker panel for pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Integrative survival-based molecular profiling of human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Nr5a2 heterozygosity sensitises to, and cooperates with, inflammation in KRas(G12V)-driven pancreatic tumourigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Gene expression profiles in pancreatic intraepithelial neoplasia reflect the effects of Hedgehog signaling on pancreatic ductal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Genome profiling of pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Frequent genomic copy number gain and overexpression of GATA-6 in pancreatic carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

GATA6 activates Wnt signaling in pancreatic cancer by negatively regulating the Wnt antagonist Dickkopf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308042

10.1136/GUTJNL-2014-308042

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25596178%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference