(Q38926363)

7 September 2017

2 references

19 September 2019

6 December 2020

False-positive findings in Cochrane meta-analyses with and without application of trial sequential analysis: an empirical review (English)

1 reference

biomedical investigative technique

7 September 2017

1 reference

6 December 2020

1 reference

19 September 2019

3

1 reference

7 September 2017

4

1 reference

7 September 2017

2

Kristian Thorlund

1 reference

7 September 2017

1

Georgina Imberger

1 reference

7 September 2017

12 August 2016

3 references

7 September 2017

19 September 2019

6 December 2020

3 references

7 September 2017

19 September 2019

6 December 2020

6

1 reference

7 September 2017

8

1 reference

7 September 2017

e011890

1 reference

Creative Commons Attribution-NonCommercial

7 September 2017

2 references

19 September 2019

6 December 2020

The knowledge system underpinning healthcare is not fit for purpose and must change

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Predictive distributions for between-study heterogeneity and simple methods for their application in Bayesian meta-analysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

HMG CoA reductase inhibitors (statins) for dialysis patients

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

The impact of study size on meta-analyses: examination of underpowered studies in Cochrane reviews

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Vaccines for preventing pneumococcal infection in adults

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Calcium antagonists for acute ischemic stroke

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Fetal electrocardiogram (ECG) for fetal monitoring during labour

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Inhaled corticosteroids versus long-acting beta2-agonists for chronic obstructive pulmonary disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

The number of patients and events required to limit the risk of overestimation of intervention effects in meta-analysis--a simulation study

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Sequential methods for random-effects meta-analysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Statistically significant meta-analyses of clinical trials have modest credibility and inflated effects

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Estimating required information size by quantifying diversity in random-effects model meta-analyses.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Effect of early treatment with anti-hypertensive drugs on short and long-term mortality in patients with an acute cardiovascular event

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Evidence synthesis as the key to more coherent and efficient research

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Apparently conclusive meta-analyses may be inconclusive--Trial sequential analysis adjustment of random error risk due to repetitive testing of accumulating data in apparently conclusive neonatal meta-analyses

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Attention should be given to multiplicity issues in systematic reviews

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Early stopping of randomized clinical trials for overt efficacy is problematic

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Antiplatelet agents for preventing pre-eclampsia and its complications

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Statistics: The Problem of Examining Accumulating Data More Than Once

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Meta-analysis in clinical trials

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Sequential meta-analysis: an efficient decision-making tool

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Updating meta-analyses leads to larger type I errors than publication bias

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Can trial sequential monitoring boundaries reduce spurious inferences from meta-analyses?

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Cumulating evidence from randomized trials: utilizing sequential monitoring boundaries for cumulative meta-analysis

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

Interim analysis: the alpha spending function approach.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4985805

A prospectively planned cumulative meta-analysis applied to a series of concurrent clinical trials

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27519923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Uncertainty of the time of first significance in random effects cumulative meta-analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27519923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Applying the law of iterated logarithm to control type I error in cumulative meta-analysis of binary outcomes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27519923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1136/BMJOPEN-2016-011890

1 reference

7 September 2017

1 reference

7 September 2017

1 reference

PMCID

4985805