(Q38936622)

7 September 2017

1 reference

title

Immunity and inflammation in diabetic kidney disease: translating mechanisms to biomarkers and treatment targets (English)

1 reference

7 September 2017

0 references

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1 reference

4

Katherine R Tuttle

1 reference

7 September 2017

Raimund Pichler

1

1 reference

7 September 2017

Maryam Afkarian

series ordinal

2

1 reference

7 September 2017

Brad P Dieter

series ordinal

3

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7 September 2017

publication date

24 August 2016

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American Journal of Physiology - Renal Physiology

7 September 2017

published in

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7 September 2017

volume

312

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7 September 2017

issue

4

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7 September 2017

page(s)

F716-F731

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Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia

7 September 2017

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Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. Possible mediation by glucose

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Interleukin-18 enhances monocyte tumor necrosis factor alpha and interleukin-1beta production induced by direct contact with T lymphocytes: implications in rheumatoid arthritis.

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High glucose induces toll-like receptor expression in human monocytes: mechanism of activation

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Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy

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Pentoxifylline ameliorates renal tumor necrosis factor expression, sodium retention, and renal hypertrophy in diabetic rats

21 January 2018

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Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy

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Long-term renal effects of a neutralizing RAGE antibody in obese type 2 diabetic mice

21 January 2018

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Renal IL-18 production is macrophage independent during obstructive injury

21 January 2018

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Leukocyte recruitment and vascular injury in diabetic nephropathy

21 January 2018

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Baricitinib in Patients with Refractory Rheumatoid Arthritis

21 January 2018

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Clinical review: The role of advanced glycation end products in progression and complications of diabetes

21 January 2018

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Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes

21 January 2018

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21 January 2018

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21 January 2018

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Effects of pentoxifylline on proteinuria and glucose control in patients with type 2 diabetes: a prospective randomized double-blind multicenter study.

21 January 2018

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Association between mannose-binding lectin and vascular complications in type 1 diabetes

21 January 2018

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Elevated levels of mannan-binding lectin in patients with type 1 diabetes

21 January 2018

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Endothelial cell-selective adhesion molecule regulates albuminuria in diabetic nephropathy

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Global Toll-like receptor 4 knockout results in decreased renal inflammation, fibrosis and podocytopathy

21 January 2018

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The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy

21 January 2018

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Tranilast reduces mesenteric vascular collagen deposition and chymase-positive mast cells in experimental diabetes

21 January 2018

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Low serum endothelial cell-selective adhesion molecule predicts increase in albuminuria in type 2 diabetes patients

21 January 2018

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DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The monocyte chemoattractant protein-1/CCR2 loop, inducible by TGF-beta, increases podocyte motility and albumin permeability.

21 January 2018

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Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes.

21 January 2018

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Anti-GBM glomerulonephritis involves IL-1 but is independent of NLRP3/ASC inflammasome-mediated activation of caspase-1.

21 January 2018

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Lymphocytes promote albuminuria, but not renal dysfunction or histological damage in a mouse model of diabetic renal injury.

21 January 2018

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Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

21 January 2018

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Inhibition of chymase protects against diabetes-induced oxidative stress and renal dysfunction in hamsters

21 January 2018

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21 January 2018

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Expression of ICAM-1 on glomeruli is associated with progression of diabetic nephropathy in a genetically obese diabetic rat, Wistar fatty.

21 January 2018

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21 January 2018

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Innate immunity: the virtues of a nonclonal system of recognition

21 January 2018

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Glomerular cell death and inflammation with high-protein diet and diabetes

21 January 2018

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Impaired IL-18 processing protects caspase-1-deficient mice from ischemic acute renal failure

21 January 2018

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CSF-1 signals directly to renal tubular epithelial cells to mediate repair in mice

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Streptozotocin-induced diabetic nephropathy in rats: the role of inflammatory cytokines

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The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

21 January 2018

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Serum interleukin-18 levels are associated with nephropathy and atherosclerosis in Japanese patients with type 2 diabetes

21 January 2018

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Renal pro-inflammatory cytokine gene expression in diabetic nephropathy: effect of angiotensin-converting enzyme inhibition and pentoxifylline administration.

21 January 2018

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Inflammatory parameters are independently associated with urinary albumin in type 2 diabetes mellitus

21 January 2018

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Urinary protein excretion and serum tumor necrosis factor in diabetic patients with advanced renal failure: effects of pentoxifylline administration

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21 January 2018

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21 January 2018

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Serum concentrations of markers of TNFalpha and Fas-mediated pathways and renal function in nonproteinuric patients with type 1 diabetes.

21 January 2018

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Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice.

21 January 2018

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Tumor necrosis factor (TNF)-alpha-induced IL-8 expression in gastric epithelial cells: role of reactive oxygen species and AP endonuclease-1/redox factor (Ref)-1.

21 January 2018

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Cloning of a new cytokine that induces IFN-gamma production by T cells

21 January 2018

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Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)

21 January 2018

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A randomized phase 2b trial of baricitinib, an oral Janus kinase (JAK) 1/JAK2 inhibitor, in patients with moderate-to-severe psoriasis.

21 January 2018

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Juxtaglomerular body abnormalities in youth-onset diabetic subjects

21 January 2018

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Bardoxolone methyl and kidney function in CKD with type 2 diabetes

21 January 2018

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Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes

21 January 2018

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Glycation inactivation of the complement regulatory protein CD59: a possible role in the pathogenesis of the vascular complications of human diabetes

21 January 2018

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Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

21 January 2018

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T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Correlation between circulating adhesion molecule levels and albuminuria in type-2 diabetic hypertensive patients.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Mast cells and type VIII collagen in human diabetic nephropathy

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

21 January 2018

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Revisiting inflammation in diabetic nephropathy: the role of the Nlrp3 inflammasome in glomerular resident cells

21 January 2018

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Increased levels of mannan-binding lectin in type 1 diabetic patients with incipient and overt nephropathy

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells

21 January 2018

1 reference

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Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy

21 January 2018

1 reference

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Soluble vascular cell adhesion molecule-1 and soluble E-selectin are associated with micro- and macrovascular complications in Type 1 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: progressive, interrelated, and independently associated with risk of death

21 January 2018

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Recent advances in the cellular and molecular biology of mast cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-beta1-dependent pathway

21 January 2018

1 reference

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TNF-alpha activation of arterioles and venules alters distribution and levels of ICAM-1 and affects leukocyte-endothelial cell interactions

21 January 2018

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Diabetic tubulopathy: an emerging entity.

21 January 2018

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Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes

21 January 2018

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Urinary levels of monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8), and renal injuries in patients with type 2 diabetic nephropathy.

21 January 2018

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CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages.

21 January 2018

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NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

21 January 2018

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Is the inflammasome a potential therapeutic target in renal disease?

21 January 2018

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Diabetic Kidney Disease: A Call to Action: Preface

21 January 2018

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The effect of ruboxistaurin on nephropathy in type 2 diabetes

21 January 2018

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Effect of ruboxistaurin on albuminuria and estimated GFR in people with diabetic peripheral neuropathy: results from a randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Interleukin-18 stimulates a positive feedback loop during renal obstruction via interleukin-18 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Gene therapy via blockade of monocyte chemoattractant protein-1 for renal fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Cellular and humoral immune responses in the early stages of diabetic nephropathy in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

The imbalance of Th17/Th1/Tregs in patients with type 2 diabetes: relationship with metabolic factors and complications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Albumin impairs renal tubular tight junctions via targeting the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Serum amyloid a and risk of death and end-stage renal disease in diabetic kidney disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Increased IL-12 and decreased IL-33 serum levels are associated with increased Th1 and suppressed Th2 cytokine profile in patients with diabetic nephropathy (CURES-134)

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Increased mast cell density in renal interstitium is correlated with relative interstitial volume, serum creatinine and urea especially in diabetic nephropathy but also in primary glomerulonephritis.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Flavones mitigate tumor necrosis factor-alpha-induced adhesion molecule upregulation in cultured human endothelial cells: role of nuclear factor-kappa B.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Antiproteinuric therapy while preventing the abnormal protein traffic in proximal tubule abrogates protein- and complement-dependent interstitial inflammation in experimental renal disease

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Role of complement in acute tubulointerstitial injury of rats with aminonucleoside nephrosis

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Human mast cells activate fibroblasts: tryptase is a fibrogenic factor stimulating collagen messenger ribonucleic acid synthesis and fibroblast chemotaxis.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

In vitro alternative pathway activation of complement by the brush border of proximal tubules of normal rat kidney

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Spontaneous immunoglobulin and complement deposition in glomeruli of diabetic rats

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Glomerular changes in mice with spontaneous hereditary diabetes.

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

In vivo localization of C3 on the brush border of proximal tubules of kidneys from nephrotic patients

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Tumor necrosis factor induces glomerular damage in the rabbit

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

Studies of the Rate of Regression of the Glomerular Lesions in Diabetic Rats Treated with Pancreatic Islet Transplantation

4 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6109808

α-Actinin-4 Is Required for Normal Podocyte Adhesion

4 November 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Aberrant activation profile of cytokines and mitogen-activated protein kinases in type 2 diabetic patients with nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

The Brush Border of Proximal Tubules of Normal Human Kidney Activates the Alternative Pathway of the Complement System In Vitroa

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Alternative pathway complement activation induces proinflammatory activity in human proximal tubular epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00314.2016

Angiotensin I Conversion by Human and Rat Chymotryptic Proteinases

21 January 2018

1 reference

12 December 2020

Juxtaglomerular apparatus T-cell infiltration affects glomerular structure in Type 1 diabetic patients

1 reference

12 December 2020

Usefulness of a highly sensitive urinary and serum IL-6 assay in patients with diabetic nephropathy

1 reference

12 December 2020

Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats

1 reference

12 December 2020

Diabetic glomerulopathy in the uninephrectomized rat resists amelioration following islet transplantation

1 reference

12 December 2020

Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy.

1 reference

12 December 2020

[Role of CD4+CD25+Foxp3+ regulatory T cells in type 2 diabetic nephropathy]

1 reference

12 December 2020

Macrophage accumulation in human progressive diabetic nephropathy

1 reference

12 December 2020

Tissue-specific induction of E-selectin in glomeruli is augmented following diabetes mellitus

1 reference

12 December 2020

Release of superoxide radicals by mouse macrophages stimulated by oxidative modification of glycated low density lipoproteins

1 reference

12 December 2020

Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy

1 reference

12 December 2020

NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy

1 reference

12 December 2020

Cyclooxygenase inhibition enhances rat interleukin 1 beta-induced growth of rat mesangial cells in culture

1 reference

12 December 2020

Transfused Macrophages Ameliorate Pancreatic and Renal Injury in Murine Diabetes Mellitus

1 reference

12 December 2020

Improved renal function in diabetic patients with acute gout treated with anakinra

1 reference

12 December 2020

Possible role of tumor necrosis factor and interleukin-1 in the development of diabetic nephropathy

1 reference

12 December 2020

Mannose-binding lectin as a predictor of microalbuminuria in type 1 diabetes: an inception cohort study

1 reference

12 December 2020

Allopurinol treatment improves renal function in patients with type 2 diabetes and asymptomatic hyperuricemia: 3-year randomized parallel-controlled study

1 reference

12 December 2020

Tranilast slows the progression of advanced diabetic nephropathy

1 reference

12 December 2020

TNF-alpha enhances colony-stimulating factor-1-induced macrophage accumulation in autoimmune renal disease

1 reference

12 December 2020

Correlation of renal tubular epithelial cell-derived interleukin-18 up-regulation with disease activity in MRL-Faslpr mice with autoimmune lupus nephritis

1 reference

12 December 2020

The role of macrophages in diabetic glomerulosclerosis

1 reference

12 December 2020

In situ hybridization of interleukin 6 in diabetic nephropathy

1 reference

12 December 2020

The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition

1 reference

12 December 2020

A central role for protein kinase C overactivity in diabetic glomerulosclerosis: implications for prevention with antioxidants, fish oil, and ACE inhibitors

1 reference

12 December 2020

Tumor necrosis factor stimulates prostaglandin production and cyclic AMP levels in rat cultured mesangial cells

1 reference

12 December 2020

Glomerular hemodynamic and structural correlations in long-term experimental diabetic rats

1 reference

12 December 2020

Detection of serum IL-6 in patients with diabetic nephropathy

1 reference

12 December 2020

Linking metabolism and immunology: diabetic nephropathy is an inflammatory disease

1 reference

12 December 2020

Enhanced glomerular Toll-like receptor 4 expression and signaling in patients with type 2 diabetic nephropathy and microalbuminuria

1 reference

12 December 2020

Toll-like receptors and danger signaling in kidney injury

1 reference

12 December 2020

Proinflammatory CD14+CD16+ monocytes are associated with microinflammation in patients with type 2 diabetes mellitus and diabetic nephropathy uremia

1 reference

12 December 2020

Complement activation accelerates glomerular injury in diabetic rats

1 reference

12 December 2020

Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes

1 reference

12 December 2020

Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease

1 reference

12 December 2020

Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes

1 reference

12 December 2020

Tubulointerstitial mast cell infiltration in glomerulonephritis

1 reference

12 December 2020

Complement activation products in the urine from proteinuric patients

1 reference

12 December 2020

Serum amyloid A and inflammation in diabetic kidney disease and podocytes

1 reference

12 December 2020

Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: relationship with diabetic nephropathy

1 reference

12 December 2020

Ultrastructural localization of the membrane attack complex of complement in human renal tissues

1 reference

12 December 2020

Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-alpha and inducible nitric oxide synthase in diabetic rat glom

1 reference

12 December 2020

Increased expression of intercellular adhesion molecule-1 (ICAM-1) in diabetic rat glomeruli: glomerular hyperfiltration is a potential mechanism of ICAM-1 upregulation

1 reference

12 December 2020

Urinary tumor necrosis factor contributes to sodium retention and renal hypertrophy during diabetes

1 reference

12 December 2020

TNF-alpha increases albumin permeability of isolated rat glomeruli through the generation of superoxide

1 reference

12 December 2020

Role of chymase in diabetic nephropathy

1 reference

12 December 2020

mRNA expression of growth factors in glomeruli from diabetic rats

1 reference

12 December 2020

10.1152/AJPRENAL.00314.2016

Identifiers

DOI

1 reference

7 September 2017

0 references

1 reference