(Q38938380)

7 September 2017

title

Activation of the bile acid receptor TGR5 enhances LPS-induced inflammatory responses in a human monocytic cell line (English)

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7 September 2017

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Kaia Mobraten

1

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7 September 2017

Tarjei Haugbro

2

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7 September 2017

Ellen Karlstrom

3

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7 September 2017

Charlotte R Kleiveland

4

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7 September 2017

Tor Lea

5

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7 September 2017

publication date

24 November 2014

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Journal of Receptors and Signal Transduction

7 September 2017

published in

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7 September 2017

volume

35

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7 September 2017

issue

5

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7 September 2017

page(s)

402-409

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Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus

7 September 2017

cites work

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Hepatic uptake of bile acids in man. Fasting and postprandial concentrations of individual bile acids in portal venous and systemic blood serum

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Identification of membrane-type receptor for bile acids (M-BAR)

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The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders

21 January 2018

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A G protein-coupled receptor responsive to bile acids

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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

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TGR5-mediated bile acid sensing controls glucose homeostasis

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Expression and function of the bile acid receptor TGR5 in Kupffer cells

21 January 2018

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TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading

21 January 2018

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Chylomicrons promote intestinal absorption of lipopolysaccharides

21 January 2018

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Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier

21 January 2018

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Increased toll-like receptor activity in patients with metabolic syndrome

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Endotoxemia is associated with an increased risk of incident diabetes

21 January 2018

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Metabolic endotoxemia initiates obesity and insulin resistance

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Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes

21 January 2018

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Bile acid-induced TGR5-dependent c-Jun-N terminal kinase activation leads to enhanced caspase 8 activation in hepatocytes

21 January 2018

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Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells

21 January 2018

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Coactivation of TLR4 and TLR2/6 coordinates an additive augmentation on IL-6 gene transcription via p38MAPK pathway in U937 mononuclear cells.

21 January 2018

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The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice

21 January 2018

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Targeting bile-acid signalling for metabolic diseases

21 January 2018

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Different signaling mechanisms regulating IL-6 expression by LPS between gingival fibroblasts and mononuclear cells: seeking the common target

21 January 2018

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Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

21 January 2018

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MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65.

21 January 2018

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p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

21 January 2018

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p38 mitogen-activated protein kinase controls NF-kappaB transcriptional activation and tumor necrosis factor alpha production through RelA phosphorylation mediated by mitogen- and stress-activated protein kinase 1 in response to Borrelia burgdorferi

21 January 2018

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Mycoplasma genitalium-derived lipid-associated membrane proteins induce activation of MAPKs, NF-kappaB and AP-1 in THP-1 cells

21 January 2018

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Interleukin-1 stimulates cytokines, prostaglandin E2 and matrix metalloproteinase-1 production via activation of MAPK/AP-1 and NF-kappaB in human gingival fibroblasts

21 January 2018

1 reference

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IL-1β and IL-6 activate inflammatory responses of astrocytes against Naegleria fowleri infection via the modulation of MAPKs and AP-1.

21 January 2018

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Insulin suppresses endotoxin-induced oxidative, nitrosative, and inflammatory stress in humans

21 January 2018

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Insulin resistance and substrate utilization in human endotoxemia

21 January 2018

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Experimental endotoxemia induces adipose inflammation and insulin resistance in humans

21 January 2018

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21 January 2018

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Modulation of the JNK pathway in liver affects insulin resistance status

21 January 2018

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Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide

21 January 2018

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A central role for JNK in obesity and insulin resistance

21 January 2018

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Prevention of fat-induced insulin resistance by salicylate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2014.986744

Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2014.986744

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2014.986744

Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2014.986744

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2014.986744

Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2014.986744

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

21 January 2018

1 reference

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Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2014.986744

10.3109/10799893.2014.986744

21 January 2018

Identifiers

DOI

1 reference

7 September 2017

1 reference