(Q38939473)

English

Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive Gi-proteins in murine BV-2 microglia cells

scientific article

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scholarly article

1 reference

Europe PubMed Central

7 September 2017

Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive Gi-proteins in murine BV-2 microglia cells (English)

1 reference

Europe PubMed Central

7 September 2017

0 references

microglial inhibitor

0 references

author name string

Boonrat Chantong

1

1 reference

Europe PubMed Central

7 September 2017

Denise V Kratschmar

2

1 reference

Europe PubMed Central

7 September 2017

Adam Lister

3

1 reference

Europe PubMed Central

7 September 2017

Alex Odermatt

4

1 reference

Europe PubMed Central

7 September 2017

publication date

19 November 2014

1 reference

Europe PubMed Central

7 September 2017

Journal of Neuroinflammation

1 reference

Europe PubMed Central

7 September 2017

11

1 reference

Europe PubMed Central

7 September 2017

190

1 reference

Europe PubMed Central

7 September 2017

copyright license

Creative Commons Attribution 4.0 International

19 November 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1186/s12974-014-0190-7

0 references

ER stress-induced cell death mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Phenformin activates the unfolded protein response in an AMP-activated protein kinase (AMPK)-dependent manner.

1 reference

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9 September 2017

Chronological changes and effects of AMP-activated kinase in the hippocampal CA1 region after transient forebrain ischemia in gerbils.

1 reference

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9 September 2017

Microglial calcium signaling in the adult, aged and diseased brain

1 reference

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9 September 2017

Calcium influx through reversed NCX controls migration of microglia

1 reference

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9 September 2017

Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury

1 reference

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9 September 2017

A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production

1 reference

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9 September 2017

Mitochondria, oxidative stress and neurodegeneration.

1 reference

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9 September 2017

Redox implications of AMPK-mediated signal transduction beyond energetic clues

1 reference

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Oxidative stress and microglial cells in Parkinson's disease

1 reference

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9 September 2017

Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury

1 reference

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9 September 2017

ATP-P2X7 receptor signaling controls basal and TNFα-stimulated glial cell proliferation

1 reference

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9 September 2017

Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia

1 reference

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9 September 2017

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Role of microglia in the process of inflammation in the hypoxic developing brain

1 reference

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9 September 2017

The role of mitochondria in neurodegenerative diseases

1 reference

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9 September 2017

Novel neuroinflammatory targets in the chronically injured spinal cord

1 reference

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9 September 2017

AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Intracellular Ca2+ storage in health and disease: a dynamic equilibrium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

AICAR (5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside) increases the production of toxic molecules and affects the profile of cytokines release in LPS-stimulated rat primary microglial cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

AMPK in the brain: its roles in energy balance and neuroprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Activation of metabotropic glutamate receptor 5 modulates microglial reactivity and neurotoxicity by inhibiting NADPH oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Dantrolene: mechanisms of neuroprotection and possible clinical applications in the neurointensive care unit

1 reference

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9 September 2017

Inositol trisphosphate receptor Ca2+ release channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Metabotropic glutamate receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Involvement of proinflammatory factors, apoptosis, caspase-3 activation and Ca2+ disturbance in microglia activation-mediated dopaminergic cell degeneration

1 reference

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9 September 2017

Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

1 reference

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9 September 2017

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

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9 September 2017

Regulation of phosphoinositide-specific phospholipase C

1 reference

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9 September 2017

Activation of murine microglial cell lines by lipopolysaccharide and interferon-gamma causes NO-mediated decreases in mitochondrial and cellular function.

1 reference

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9 September 2017

Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

9 September 2017

Pharmacology and functions of metabotropic glutamate receptors

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9 September 2017

Ca(2+) spiking activity caused by the activation of store-operated Ca(2+) channels mediates TNF-α release from microglial cells under chronic purinergic stimulation

1 reference

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Activation of AMP-activated protein kinase alleviates homocysteine-mediated neurotoxicity in SH-SY5Y cells

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1 reference

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9 September 2017

Neurotoxic effects of bisphenol AF on calcium-induced ROS and MAPKs

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Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions

1 reference

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9 September 2017

Activation of AMP-kinase by AICAR induces apoptosis of DU-145 prostate cancer cells through generation of reactive oxygen species and activation of c-Jun N-terminal kinase

1 reference

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9 September 2017

Berberine suppresses neuroinflammatory responses through AMP-activated protein kinase activation in BV-2 microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

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The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

1 reference

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Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells.

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14 September 2017

Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors

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A prolonged pharmacological blockade of type-5 metabotropic glutamate receptors protects cultured spinal cord motor neurons against excitotoxic death.

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Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

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17 June 2018

Activation of metabotropic glutamate receptor 5 reduces the secondary brain injury after traumatic brain injury in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4240888

21 August 2018

Expression and cell distribution of metabotropic glutamate receptor 5 in the rat cortex following traumatic brain injury.

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21 August 2018

5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.

1 reference

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21 August 2018

Expression and signaling of group I metabotropic glutamate receptors in astrocytes and microglia.

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21 August 2018

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https://pubmed.ncbi.nlm.nih.gov/25407356

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https://pubmed.ncbi.nlm.nih.gov/25407356

12 December 2020

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Subtype selective antagonism of substantia nigra pars compacta Group I metabotropic glutamate receptors protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo

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https://pubmed.ncbi.nlm.nih.gov/25407356

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1 reference

https://pubmed.ncbi.nlm.nih.gov/25407356

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12974-014-0190-7

1 reference

Europe PubMed Central

7 September 2017

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1 reference

Europe PubMed Central

7 September 2017

1 reference

Europe PubMed Central

7 September 2017

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