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c-Abl antagonizes the YAP oncogenic function.
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PMCID
4423178
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
title
c-Abl antagonizes the YAP oncogenic function
(English)
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Europe PubMed Central
PMCID
4423178
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
author
Inna Ricardo-Lax
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3
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PMCID
4423178
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
Ziv Porat
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5
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4423178
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
Nina Reuven
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6
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4423178
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22 February 2020
author name string
R Keshet
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1
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4423178
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22 February 2020
J Adler
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2
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PMCID
4423178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
M Shanzer
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4
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PMCID
4423178
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
Y Shaul
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7
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4423178
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22 February 2020
publication date
31 October 2014
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4423178
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22 February 2020
published in
Cell Death & Differentiation
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PMCID
4423178
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
volume
22
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PMCID
4423178
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
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22 February 2020
issue
6
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Europe PubMed Central
PMCID
4423178
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
page(s)
935-945
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Europe PubMed Central
PMCID
4423178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4423178/fullTextXML
based on heuristic
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exact match
https://scigraph.springernature.com/pub.10.1038/cdd.2014.182
0 references
cites work
YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
PTPN14 is required for the density-dependent control of YAP1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade
1 reference
stated in
PubMed Central
reference URL
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retrieved
9 September 2017
YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
PTPN14 interacts with and negatively regulates the oncogenic function of YAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
WW domain interactions regulate the Hippo tumor suppressor pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Role of YAP/TAZ in mechanotransduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Modularity in the Hippo signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
The Hippo pathway regulates Wnt/beta-catenin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors
1 reference
stated in
PubMed Central
reference URL
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The basics of epithelial-mesenchymal transition
1 reference
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PubMed Central
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9 September 2017
TEAD mediates YAP-dependent gene induction and growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
YAP1 increases organ size and expands undifferentiated progenitor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Elucidation of a universal size-control mechanism in Drosophila and mammals
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Filling out the Hippo pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Hippo signaling in organ size control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma
2 references
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Physical interaction with Yes-associated protein enhances p73 transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
9 September 2017
Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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9 September 2017
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1 reference
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PubMed Central
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9 September 2017
YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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1 reference
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PubMed Central
reference URL
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14 September 2017
Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
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14 September 2017
Autoinhibition of c-Abl
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
25 September 2017
Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
25 September 2017
The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
21 August 2018
Drosophila Pez acts in Hippo signaling to restrict intestinal stem cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
21 August 2018
The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4423178
retrieved
21 August 2018
Identifiers
DOI
10.1038/CDD.2014.182
1 reference
stated in
Europe PubMed Central
PMCID
4423178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
PMCID
4423178
1 reference
stated in
Europe PubMed Central
PMCID
4423178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
PubMed ID
25361080
1 reference
stated in
Europe PubMed Central
PMCID
4423178
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25361080%20AND%20SRC:MED&resulttype=core&format=json
retrieved
22 February 2020
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