(Q38946644)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

3-Bromopyruvate induces rapid human prostate cancer cell death by affecting cell energy metabolism, GSH pool and the glyoxalase system (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

ChEBI release 2020-05-28

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1 reference

1

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28 February 2020

Rosa Anna Vacca

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

Lidia de Bari

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

publication date

3 November 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

Journal of Bioenergetics and Biomembranes

28 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

47

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

6

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28 February 2020

page(s)

493-506

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency

28 February 2020

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Role of glyoxalase I in the proliferation and apoptosis control of human LNCaP and PC3 prostate cancer cells

21 January 2018

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A novel mechanism of methylglyoxal cytotoxicity in prostate cancer cells

21 January 2018

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Selective inhibition of mitochondrial respiration and glycolysis in human leukaemic leucocytes by methylglyoxal

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Mitochondrial respiratory chain Complexes I and IV are impaired by β-amyloid via direct interaction and through Complex I-dependent ROS production, respectively.

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A possible regulatory role of glyoxalase I in cell viability of human prostate cancer

21 January 2018

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Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers

21 January 2018

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Prostate cancer cells metabolize d-lactate inside mitochondria via a D-lactate dehydrogenase which is more active and highly expressed than in normal cells

21 January 2018

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3-bromopyruvate inhibits glycolysis, depletes cellular glutathione, and compromises the viability of cultured primary rat astrocytes.

21 January 2018

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Zinc as an anti-tumor agent in prostate cancer and in other cancers

21 January 2018

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Mitochondria: 3-bromopyruvate vs. mitochondria? A small molecule that attacks tumors by targeting their bioenergetic diversity.

21 January 2018

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Hypoxia and the metabolic phenotype of prostate cancer cells

21 January 2018

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Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications

21 January 2018

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The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I

21 January 2018

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Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase

21 January 2018

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Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP.

21 January 2018

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A translational study "case report" on the small molecule "energy blocker" 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside

21 January 2018

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Otto Warburg's contributions to current concepts of cancer metabolism

21 January 2018

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Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains

21 January 2018

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Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer

21 January 2018

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Effect of metabolic inhibitors on ATP and citrate content in PC3 prostate cancer cells

21 January 2018

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Anti-AGEing defences against Alzheimer's disease

21 January 2018

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Bioenergetic and antiapoptotic properties of mitochondria from cultured human prostate cancer cell lines PC-3, DU145 and LNCaP.

21 January 2018

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Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate

21 January 2018

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Lactate transporters in the context of prostate cancer metabolism: what do we know?

21 January 2018

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Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.

21 January 2018

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Monocarboxylate transporter 2 (MCT2) as putative biomarker in prostate cancer

21 January 2018

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Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy

21 January 2018

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Purification and characterization of two forms of glyoxalase II from the liver and brain of Wistar rats.

21 January 2018

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3-Bromopyruvate induces necrotic cell death in sensitive melanoma cell lines

21 January 2018

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Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease

21 January 2018

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Methylglyoxal induces mitochondrial dysfunction and cell death in liver

21 January 2018

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3-Bromopyruvate: targets and outcomes

21 January 2018

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Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.

21 January 2018

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Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy

21 January 2018

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Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells

21 January 2018

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Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile

21 January 2018

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A convenient one-step extraction of cellular ATP using boiling water for the luciferin-luciferase assay of ATP.

21 January 2018

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Anticancer efficacy of the metabolic blocker 3-bromopyruvate: specific molecular targeting

21 January 2018

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12 December 2020

Intracellular ATP levels determine cell death fate by apoptosis or necrosis.

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12 December 2020

Cold Atmospheric Plasma Treatment Induces Anti-Proliferative Effects in Prostate Cancer Cells by Redox and Apoptotic Signaling Pathways

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12 December 2020

Effect of 3-bromopyruvic acid on human erythrocyte antioxidant defense system

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12 December 2020

Three spectrophotometric assays for the measurement of the five respiratory chain complexes in minuscule biological samples

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12 December 2020

Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress

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12 December 2020

Novel therapy for liver cancer: direct intraarterial injection of a potent inhibitor of ATP production.

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12 December 2020

L-lactate metabolism can occur in normal and cancer prostate cells via the novel mitochondrial L-lactate dehydrogenase

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12 December 2020

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pyruvylated during 3-bromopyruvate mediated cancer cell death

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12 December 2020

Differential inhibition/inactivation of mitochondrial complex I implicates its alteration in malignant cells

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 February 2020

1030232525

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26530987%20AND%20SRC:MED&resulttype=core&format=json