(Q38949698)

English

Double-negative feedback loop between ZEB2 and miR-145 regulates epithelial-mesenchymal transition and stem cell properties in prostate cancer cells

scientific article published on 9 October 2014

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scholarly article

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Europe PubMed Central

PubMed publication ID

7 September 2017

Double-negative feedback loop between ZEB2 and miR-145 regulates epithelial-mesenchymal transition and stem cell properties in prostate cancer cells (English)

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Europe PubMed Central

PubMed publication ID

7 September 2017

prostate cancer

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based on heuristic

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object named as

Dong Ren

1

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author name string

Min Wang

2

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Europe PubMed Central

PubMed publication ID

7 September 2017

Wei Guo

3

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Shuai Huang

4

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Zeyu Wang

5

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Xiaohui Zhao

6

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Hong Du

7

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Europe PubMed Central

PubMed publication ID

7 September 2017

Libing Song

8

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Europe PubMed Central

PubMed publication ID

7 September 2017

Xinsheng Peng

9

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Europe PubMed Central

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7 September 2017

publication date

9 October 2014

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Europe PubMed Central

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7 September 2017

Cell and Tissue Research

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Europe PubMed Central

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7 September 2017

358

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Europe PubMed Central

PubMed publication ID

7 September 2017

3

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Europe PubMed Central

PubMed publication ID

7 September 2017

763-778

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Europe PubMed Central

PubMed publication ID

7 September 2017

https://scigraph.springernature.com/pub.10.1007/s00441-014-2001-y

0 references

MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

The functions of animal microRNAs

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

The Snail genes as inducers of cell movement and survival: implications in development and cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Three clonal types of keratinocyte with different capacities for multiplication

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

MiR-34 and SNAIL: another double-negative feedback loop controlling cellular plasticity/EMT governed by p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma

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21 January 2018

A perspective on cancer cell metastasis

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21 January 2018

Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2.

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https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Abate and switch: miR-145 in stem cell differentiation.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Snail1 induces epithelial-to-mesenchymal transition and tumor initiating stem cell characteristics

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

MicroRNA-145 targets vascular endothelial growth factor and inhibits invasion and metastasis of osteosarcoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Protein expression of ZEB2 in renal cell carcinoma and its prognostic significance in patient survival

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Microenvironmental regulation of epithelial-mesenchymal transitions in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Overexpression of TWIST2 correlates with poor prognosis in head and neck squamous cell carcinomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Mesenchymal-epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

HEF1 promotes epithelial mesenchymal transition and bone invasion in prostate cancer under the regulation of microRNA-145

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Hallmarks of Cancer: The Next Generation

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

δEF1 promotes osteolytic metastasis of MDA-MB-231 breast cancer cells by regulating MMP-1 expression

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Retracted: MiR-145 Regulates Epithelial to Mesenchymal Transition of Breast Cancer Cells by Targeting Oct4

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

MicroRNAs as post-transcriptional machines and their interplay with cellular networks

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Biological roles and prognostic values of the epithelial-mesenchymal transition-mediating transcription factors Twist, ZEB1 and Slug in diffuse large B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

c-MYC delays prometaphase by direct transactivation of MAD2 and BubR1: identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Association of human DNA topoisomerase IIalpha with mitotic chromosomes in mammalian cells is independent of its catalytic activity

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Cancer stemness and metastasis: therapeutic consequences and perspectives

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Smad interacting protein 1 (SIP1) is associated with peritoneal carcinomatosis in intestinal type gastric cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Prognostic value of microvessel density and p53 expression on the locoregional metastasis and survival of the patients with head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays.

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Stem cell characteristics in prostate cancer cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Epithelial to mesenchymal transition by TGFβ-1 induction increases stemness characteristics in primary non small cell lung cancer cell line

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

The increasing complexity of the cancer stem cell paradigm

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Heterogeneity in cancer: cancer stem cells versus clonal evolution

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Complex networks orchestrate epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Linkage between Twist1 and Bmi1: molecular mechanism of cancer metastasis/stemness and clinical implications

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

Establishing human prostate cancer cell xenografts in bone: induction of osteoblastic reaction by prostate-specific antigen-producing tumors in athymic and SCID/bg mice using LNCaP and lineage-derived metastatic sublines

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

The bisphosphonate olpadronate inhibits skeletal prostate cancer progression in a green fluorescent protein nude mouse model

1 reference

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21 January 2018

miR-145 suppresses cell invasion in hepatocellular carcinoma cells: miR-145 targets ADAM17.

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21 January 2018

Current perspectives in intronic micro RNAs (miRNAs).

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21 January 2018

Enhancement of cancer stem-like and epithelial-mesenchymal transdifferentiation property in oral epithelial cells with long-term nicotine exposure: reversal by targeting SNAIL.

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21 January 2018

MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha

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21 January 2018

miRNA-145 targets v-ets erythroblastosis virus E26 oncogene homolog 1 to suppress the invasion, metastasis, and angiogenesis of gastric cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00441-014-2001-Y

21 January 2018

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10.1007/S00441-014-2001-Y

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Europe PubMed Central

PubMed publication ID

7 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

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