(Q38952589)

7 September 2017

title

TRIM35 Interacts with pyruvate kinase isoform M2 to suppress the Warburg effect and tumorigenicity in hepatocellular carcinoma (English)

1 reference

7 September 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Xianghuo He

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Z Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

W Guo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Z Zhang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

F Zhao

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Y Zhao

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

D Jia

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

J Ding

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

H Wang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

M Yao

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

29 September 2014

1 reference

7 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

3946-3956

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263439%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2014.325

4 June 2020

exact match

0 references

cites work

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Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

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PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis

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Pyruvate kinase M2 is a phosphotyrosine-binding protein

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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

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Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland

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Pyruvate kinase type M2 and its role in tumor growth and spreading

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Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

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Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation

31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25263439