(Q38953922)

English

Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models

scientific article published on 10 September 2014

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

7 September 2017

Volitinib, a potent and highly selective c-Met inhibitor, effectively blocks c-Met signaling and growth in c-MET amplified gastric cancer patient-derived tumor xenograft models (English)

1 reference

Europe PubMed Central

7 September 2017

1 reference

based on heuristic

inferred from title

tumour xenograft

1 reference

based on heuristic

inferred from title

author name string

Paul R Gavine

1

1 reference

Europe PubMed Central

7 September 2017

Yongxin Ren

2

1 reference

Europe PubMed Central

7 September 2017

Lu Han

3

1 reference

Europe PubMed Central

7 September 2017

Jing Lv

4

1 reference

Europe PubMed Central

7 September 2017

Shiming Fan

5

1 reference

Europe PubMed Central

7 September 2017

Wei Zhang

6

1 reference

Europe PubMed Central

7 September 2017

Wen Xu

7

1 reference

Europe PubMed Central

7 September 2017

Yuan Jie Liu

8

1 reference

Europe PubMed Central

7 September 2017

Tianwei Zhang

9

1 reference

Europe PubMed Central

7 September 2017

Haihua Fu

10

1 reference

Europe PubMed Central

7 September 2017

Yongjuan Yu

11

1 reference

Europe PubMed Central

7 September 2017

Huiying Wang

12

1 reference

Europe PubMed Central

7 September 2017

Shirlian Xu

13

1 reference

Europe PubMed Central

7 September 2017

Feng Zhou

14

1 reference

Europe PubMed Central

7 September 2017

Xinying Su

15

1 reference

Europe PubMed Central

7 September 2017

XiaoLu Yin

16

1 reference

Europe PubMed Central

7 September 2017

Liang Xie

17

1 reference

Europe PubMed Central

7 September 2017

Linfang Wang

18

1 reference

Europe PubMed Central

7 September 2017

Weiguo Qing

19

1 reference

Europe PubMed Central

7 September 2017

Longxian Jiao

20

1 reference

Europe PubMed Central

7 September 2017

Weiguo Su

21

1 reference

Europe PubMed Central

7 September 2017

Q May Wang

22

1 reference

Europe PubMed Central

7 September 2017

publication date

10 September 2014

1 reference

Europe PubMed Central

7 September 2017

Molecular Oncology

1 reference

Europe PubMed Central

7 September 2017

9

1 reference

Europe PubMed Central

7 September 2017

323-333

1 reference

Europe PubMed Central

7 September 2017

1

1 reference

Europe PubMed Central

7 September 2017

HER2, MET and FGFR2 oncogenic driver alterations define distinct molecular segments for targeted therapies in gastric carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Phase II study evaluating 2 dosing schedules of oral foretinib (GSK1363089), cMET/VEGFR2 inhibitor, in patients with metastatic gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

The emerging role of MET/HGF inhibitors in oncology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyraz

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

MET in gastric carcinomas: comparison between protein expression and gene copy number and impact on clinical outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Durable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Targeting MET in cancer: rationale and progress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

MET expression and amplification in patients with localized gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Why does Japan have a high incidence of gastric cancer? Comparison of gastritis between UK and Japanese patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

The global health burden of infection-associated cancers in the year 2002

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Met, metastasis, motility and more

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Hepatocyte growth factor and its receptor (c-MET) in prostatic carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Molecular cloning and expression of human hepatocyte growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

FGFR2 gene amplification in gastric cancer predicts sensitivity to the selective FGFR inhibitor AZD4547.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

9 September 2017

Cloning of a cancer cell-producing hepatocyte growth factor, vascular endothelial growth factor, and interleukin-8 from gastric cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

14 September 2017

Emerging multipotent aspects of hepatocyte growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

25 September 2017

Activation of c-Met (hepatocyte growth factor receptor) in human gastric cancer tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

17 June 2018

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

17 June 2018

The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

17 June 2018

Frequent amplification of the c-met gene in scirrhous type stomach cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

17 June 2018

Expression of c-met/HGF receptor in human non-small cell lung carcinomas in vitro and in vivo and its prognostic significance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

3 July 2018

c-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

21 August 2018

High MET gene copy number leads to shorter survival in patients with non-small cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

21 August 2018

Phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor growth and prognosis in patients with bladder cancer: correlation with matrix metalloproteinase-2 and -7 and E-cadherin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

21 August 2018

Polysomy 17 in breast cancer: clinicopathologic significance and impact on HER-2 testing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

21 August 2018

Overexpression of the c-met protooncogene in human gastric carcinoma--correlation to clinical features.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528670

21 August 2018

Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the hepatocyte growth factor/c-Met pathway is increased at the cancer front in breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of c-myc, K-sam, and c-met in gastric cancers: detection by fluorescence in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of c-met proto-oncogene in primary colorectal cancer and liver metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of the c-met, c-erbB-2 and epidermal growth factor receptor gene in human gastric cancers: correlation to clinical features

1 reference

https://pubmed.ncbi.nlm.nih.gov/25248999

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLONC.2014.08.015

1 reference

Europe PubMed Central

7 September 2017

1 reference

Europe PubMed Central

7 September 2017

1 reference

Europe PubMed Central

7 September 2017

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