(Q38964460)

English

Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair

scientific article published on 20 August 2014

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair (English)

1 reference

Europe PubMed Central

8 September 2017

esophageal squamous cell carcinoma

1 reference

based on heuristic

inferred from title

author name string

Qin Qin

1

1 reference

Europe PubMed Central

8 September 2017

Hongyan Cheng

2

1 reference

Europe PubMed Central

8 September 2017

Jing Lu

3

1 reference

Europe PubMed Central

8 September 2017

Liangliang Zhan

4

1 reference

Europe PubMed Central

8 September 2017

Jianchao Zheng

5

1 reference

Europe PubMed Central

8 September 2017

Jing Cai

6

1 reference

Europe PubMed Central

8 September 2017

Xi Yang

7

1 reference

Europe PubMed Central

8 September 2017

Liping Xu

8

1 reference

Europe PubMed Central

8 September 2017

Hongcheng Zhu

9

1 reference

Europe PubMed Central

8 September 2017

Chi Zhang

10

1 reference

Europe PubMed Central

8 September 2017

Jia Liu

11

1 reference

Europe PubMed Central

8 September 2017

Jianxin Ma

12

1 reference

Europe PubMed Central

8 September 2017

Xizhi Zhang

13

1 reference

Europe PubMed Central

8 September 2017

Shengbin Dai

14

1 reference

Europe PubMed Central

8 September 2017

Xinchen Sun

15

1 reference

Europe PubMed Central

8 September 2017

publication date

20 August 2014

1 reference

Europe PubMed Central

8 September 2017

Journal of Hematology & Oncology

1 reference

Europe PubMed Central

8 September 2017

7

1 reference

Europe PubMed Central

8 September 2017

62

1 reference

Europe PubMed Central

8 September 2017

copyright license

Creative Commons Attribution 4.0 International

20 August 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1186/s13045-014-0062-8

0 references

Smac mimetic compound LCL161 sensitizes esophageal carcinoma cells to radiotherapy by inhibiting the expression of inhibitor of apoptosis protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Targeting Polo-like kinase in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Targeting survivin in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

The universal character of the tumor-associated antigen survivin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

MDC1 regulates DNA-PK autophosphorylation in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Survivin, versatile modulation of cell division and apoptosis in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

The interplay between nonhomologous end-joining and cell cycle checkpoint factors in development, genomic stability, and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Validating survivin as a cancer therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Expression of survivin in esophageal cancer: correlation with the prognosis and response to chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Control of apoptosis and mitotic spindle checkpoint by survivin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Effects and mechanism of downregulation of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Survivin siRNA inhibits gastric cancer in nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

High expression of survivin predicts poor prognosis in esophageal squamous cell carcinoma following radiotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

Antitumor activity of YM155, a selective small-molecule survivin suppressant, alone and in combination with docetaxel in human malignant melanoma models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

9 September 2017

YM155, a novel survivin suppressant, enhances taxane-induced apoptosis and tumor regression in a human Calu 6 lung cancer xenograft model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

14 September 2017

Antitumor effects of YM155, a novel survivin suppressant, against human aggressive non-Hodgkin lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

14 September 2017

Down-regulation of survivin by oxaliplatin diminishes radioresistance of head and neck squamous carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

14 September 2017

Prognostic significance of survivin expression in renal cell cancer and its correlation with radioresistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

14 September 2017

Adenovirus-mediated transfer of siRNA against survivin enhances the radiosensitivity of human non-small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

14 September 2017

Survivin as a radioresistance factor, and prognostic and therapeutic target for radiotherapy in rectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

14 September 2017

Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

14 September 2017

Chk1, but not Chk2, is involved in the cellular response to DNA damaging agents: differential activity in cells expressing or not p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

14 September 2017

siRNA targeting survivin inhibits the growth and enhances the chemosensitivity of hepatocellular carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

Survivin as a prognostic marker for urothelial carcinoma of the bladder: a multicenter external validation study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

Immunohistochemical analysis of nuclear survivin expression in esophageal squamous cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

Checkpoint abrogation in G2 compromises repair of chromosomal breaks in ataxia telangiectasia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

Human Chk1 expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237864

21 August 2018

Treating cutis verticis gyrata using skin expansion method.

1 reference

https://api.crossref.org/works/10.1186%2FS13045-014-0062-8

21 January 2018

Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/25139395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear survivin expression predicts poorer prognosis in glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25139395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survivin in esophageal cancer: An accurate prognostic marker for squamous cell carcinoma but not adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25139395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13045-014-0062-8

1 reference

https://api.fatcat.wiki/v0/release/m4gttlussfh2fhnq2oiitynfra

30 July 2022

based on heuristic

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Dimensions Publication ID

0 references

release_m4gttlussfh2fhnq2oiitynfra

1 reference

https://api.fatcat.wiki/v0/release/m4gttlussfh2fhnq2oiitynfra

30 July 2022

based on heuristic

mapped directly with Wikidata item

1 reference

https://api.fatcat.wiki/v0/release/m4gttlussfh2fhnq2oiitynfra

30 July 2022

based on heuristic

mapped directly with Wikidata item

1 reference

https://api.fatcat.wiki/v0/release/m4gttlussfh2fhnq2oiitynfra

30 July 2022

based on heuristic

mapped directly with Wikidata item

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