(Q35591693)

9 August 2017

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title

Survivin, versatile modulation of cell division and apoptosis in cancer (English)

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9 August 2017

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Dario C Altieri

1

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PubMed ID

14634620

9 August 2017

language of work or name

English

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publication date

1 November 2003

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9 August 2017

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9 August 2017

22

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9 August 2017

8581-8589

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9 August 2017

53

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207113

9 August 2017

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cites work

Chromosomal passengers and the (aurora) ABCs of mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Expression and prognostic significance of survivin in de novo acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Validating survivin as a cancer therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Activation of cancer-specific gene expression by the survivin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Cytokine-regulated expression of survivin in myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Ribozyme-mediated cleavage of the human survivin mRNA and inhibition of antiapoptotic function of survivin in MCF-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Proliferation, cell cycle and apoptosis in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Regulation of the inhibitor-of-apoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: implication of survivin expression in normal hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Survivin, bcl-2, bax, and bcl-X gene expression in sentinel lymph nodes from melanoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Mechanisms which mediate the antiapoptotic effects of angiopoietin-1 on endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

survivin messenger RNA expression is a good prognostic biomarker for oesophageal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Participation of Survivin in mitotic and apoptotic activities of normal and tumor-derived cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Deterin, a new inhibitor of apoptosis from Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Expression of survivin in astrocytic tumors: correlation with malignant grade and prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Aberrant expression of caspase cascade regulatory genes in adult T-cell leukaemia: survivin is an important determinant for prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Livin, a novel inhibitor of apoptosis protein family member

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Expression of survivin in esophageal cancer: correlation with the prognosis and response to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Control of apoptosis and mitotic spindle checkpoint by survivin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Interleukin-11 up-regulates survivin expression in endothelial cells through a signal transducer and activator of transcription-3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Differential subcellular localization of functionally divergent survivin splice variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Cancer gene therapy using a survivin mutant adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Survivin mRNA is down-regulated during early Xenopus laevis embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Control of apoptosis during angiogenesis by survivin expression in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

A p34(cdc2) survival checkpoint in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Radiosensitization of human melanoma cells by ribozyme-mediated inhibition of survivin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Complexities in the development of cyclin-dependent kinase inhibitor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Survivin is a shared tumor-associated antigen expressed in a broad variety of malignancies and recognized by specific cytotoxic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Phase I study of the cyclin-dependent kinase inhibitor flavopiridol in combination with paclitaxel in patients with advanced solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Chromosome dynamics: new light on Aurora B kinase function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Human survivin is a kinetochore-associated passenger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

A role for survivin in chemoresistance of endothelial cells mediated by VEGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

STAT proteins: novel molecular targets for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Gene expression profiling predicts clinical outcome of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Analysis of human transcriptomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Structural basis for phosphoserine-proline recognition by group IV WW domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Co-expression of survivin and TERT and risk of tumour-related death in patients with soft-tissue sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Downregulation of survivin expression by induction of the effector cell protease receptor-1 reduces tumor growth potential and results in an increased sensitivity to anticancer agents in human colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Hodgkin and Reed-Sternberg cells harbor alterations in the major tumor suppressor pathways and cell-cycle checkpoints: analyses using tissue microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Quantitatively determined survivin expression levels are of prognostic value in human gliomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

The antiapoptosis protein survivin is associated with cell cycle entry of normal cord blood CD34(+) cells and modulates cell cycle and proliferation of mouse hematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Effect of intravesical treatment of transitional cell carcinoma with bacillus Calmette-Guerin and mitomycin C on urinary survivin levels and outcome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Relationship between expression of genes involved in cell cycle control and apoptosis in diffuse large B cell lymphoma: a preferential survivin–cyclin B link

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Tumor Content of the Antiapoptosis Molecule Survivin and Recurrence of Bladder Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207113

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207113

1 reference

9 August 2017

1 reference

PubMed ID

14634620