(Q38972708)

8 September 2017

title

Blockade of CD40-TRAF2,3 or CD40-TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells (English)

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8 September 2017

Carlos S Subauste

5

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author name string

Jose-Andres C Portillo

1

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8 September 2017

Jennifer A Greene

2

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8 September 2017

Isaac Schwartz

3

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8 September 2017

Maria Cecilia Subauste

4

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8 September 2017

publication date

1 January 2015

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8 September 2017

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8 September 2017

volume

144

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8 September 2017

issue

1

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8 September 2017

page(s)

21-33

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CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

8 September 2017

cites work

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CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.

21 January 2018

1 reference

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis

21 January 2018

1 reference

Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154.

21 January 2018

1 reference

CD40 and autoimmunity: the dark side of a great activator.

21 January 2018

1 reference

The CD40-CD40L pathway contributes to the proinflammatory function of intestinal epithelial cells in inflammatory bowel disease

21 January 2018

1 reference

Crucial role of CD40 signaling in vascular wall cells in neointimal formation and vascular remodeling after vascular interventions

21 January 2018

1 reference

CD40 ligand-dependent tyrosine nitration of prostacyclin synthase in vivo

21 January 2018

1 reference

CD40 ligand (CD154) stimulation of macrophages to produce HIV-1-suppressive beta-chemokines

21 January 2018

1 reference

CD40-mediated activation of vascular smooth muscle cell chemokine production through a Src-initiated, MAPK-dependent pathway

21 January 2018

1 reference

TNF receptor-associated factor 6 is an essential mediator of CD40-activated proinflammatory pathways in monocytes and macrophages.

21 January 2018

1 reference

Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor.

21 January 2018

1 reference

Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture?

21 January 2018

1 reference

CD40 ligation induces tissue factor expression in human vascular smooth muscle cells

21 January 2018

1 reference

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion

21 January 2018

1 reference

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

21 January 2018

1 reference

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

21 January 2018

1 reference

Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice

21 January 2018

1 reference

Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype

21 January 2018

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The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling

21 January 2018

1 reference

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

21 January 2018

1 reference

CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization

21 January 2018

1 reference

CD40 signaling through a newly identified tumor necrosis factor receptor-associated factor 2 (TRAF2) binding site

21 January 2018

1 reference

The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells

21 January 2018

1 reference

Distinct contributions of different CD40 TRAF binding sites to CD154-induced dendritic cell maturation and IL-12 secretion

21 January 2018

1 reference

CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes

21 January 2018

1 reference

CD40 and tumour necrosis factor-α co-operate to up-regulate inducuble nitric oxide synthase expression in macrophages.

21 January 2018

1 reference

TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells

21 January 2018

1 reference

CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells

21 January 2018

1 reference

TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.

21 January 2018

1 reference

The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen

21 January 2018

1 reference

Human dendritic cells discriminate between viable and killed Toxoplasma gondii tachyzoites: dendritic cell activation after infection with viable parasites results in CD28 and CD40 ligand signaling that controls IL-12-dependent and -independent T ce

21 January 2018

1 reference

CD40 mediates retinal inflammation and neurovascular degeneration

21 January 2018

1 reference

Characterization of the roles of TNF receptor-associated factor 6 in CD40-mediated B lymphocyte effector functions

21 January 2018

1 reference

Cutting edge: molecular mechanisms of synergy between CD40 and the B cell antigen receptor: role for TNF receptor-associated factor 2 in receptor interaction.

21 January 2018

1 reference

Antibodies to intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 prevent crescent formation in rat autoimmune glomerulonephritis

21 January 2018

1 reference

Intercellular Adhesion Molecule-1–Deficient Mice Are Resistant Against Renal Injury After Induction of Diabetes

21 January 2018

1 reference

Specific peptides for the therapeutic targeting of oncogenes

21 January 2018

1 reference

Role of vascular cell adhesion molecule-1 and fibronectin connecting segment-1 in monocyte rolling and adhesion on early atherosclerotic lesions.

21 January 2018

1 reference

Matrix metalloproteinase inhibition therapy for vascular diseases

21 January 2018

1 reference

Therapeutic applications of cell-penetrating peptides

21 January 2018

1 reference

Expression of CD40 and its ligand, CD40L, in intestinal lesions of Crohn's disease

21 January 2018

1 reference

CD40-CD40 ligand mediates the recruitment of leukocytes and platelets in the inflamed murine colon

21 January 2018

1 reference

12 December 2020

CD40-TRAF6 and autophagy-dependent anti-microbial activity in macrophages

1 reference

12 December 2020

IL-4 and IL-13 augment cytokine- and CD40-induced RANTES production by human renal tubular epithelial cells in vitro

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12 December 2020

CD40 expression on graft infiltrates and parenchymal CD154 (CD40L) induction in human chronic renal allograft rejection

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12 December 2020

Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice

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12 December 2020

Effects of the anti-ICAM-1 monoclonal antibody on dextran sodium sulphate-induced colitis in rats

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12 December 2020

The TRAF6, but not the TRAF2/3, binding domain of CD40 is required for cytokine production in human lung fibroblasts

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12 December 2020

Membrane-bound CD154, but not CD40-specific antibody, mediates NF-kappaB-independent IL-6 production in B cells

1 reference

12 December 2020

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12 December 2020

Cell adhesion molecule expression in murine lupus-like nephritis induced by lipopolysaccharide

1 reference

12 December 2020

Prevention of experimental colitis in SCID mice reconstituted with CD45RBhigh CD4+ T cells by blocking the CD40-CD154 interactions

1 reference

12 December 2020

Macrophages, smooth muscle cells, endothelial cells, and T-cells express CD40 and CD40L in fatty streaks and more advanced human atherosclerotic lesions. Colocalization with epitopes of oxidized low-density lipoprotein, scavenger receptor, and CD16

1 reference

12 December 2020

Expression of CD40 in vascular smooth muscle cells and macrophages is associated with early development of human atherosclerotic lesions

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12 December 2020

Function of CD40/CD40L in peritubular capillary of renal allograft rejection

1 reference

12 December 2020

Analysis of the oligomeric requirement for signaling by CD40 using soluble multimeric forms of its ligand, CD154

1 reference

12 December 2020

CD40 ligation stimulates MCP-1 and IL-8 production, TRAF6 recruitment, and MAPK activation in proximal tubule cells

1 reference

12 December 2020

Importance of monocyte chemoattractant protein-1 pathway in neointimal hyperplasia after periarterial injury in mice and monkeys

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12 December 2020

Mechanisms of TNF receptor-associated factor (TRAF) regulation in B lymphocytes.

1 reference

12 December 2020

The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching

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12 December 2020

A short course of BG9588 (anti-CD40 ligand antibody) improves serologic activity and decreases hematuria in patients with proliferative lupus glomerulonephritis

1 reference

12 December 2020

Platelets trigger a CD40-dependent inflammatory response in the microvasculature of inflammatory bowel disease patients

1 reference

12 December 2020

Intrinsic renal cell expression of CD40 directs Th1 effectors inducing experimental crescentic glomerulonephritis

1 reference

12 December 2020

Mesangial expression of intercellular adhesion molecule-1 in primary glomerulosclerosis

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12 December 2020

Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis.

1 reference

12 December 2020

Immunohistologic analysis of renal CD40 and CD40L expression in lupus nephritis and other glomerulonephritides

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12 December 2020

Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells

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12 December 2020

Deficiency of inflammatory cell adhesion molecules protects against atherosclerosis in mice

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12 December 2020

Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes.

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12 December 2020

TNF receptor-associated factor 6-dependent CD40 signaling primes macrophages to acquire antimicrobial activity in response to TNF-alpha

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12 December 2020

Identifiers

DOI

10.1111/IMM.12361

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8 September 2017

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