(Q38986437)

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A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels.

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24913304%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53(mut) exhibits ATP-binding cassette transporter upregulation and high glutathione levels (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24913304%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

head and neck cancer

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

head and neck carcinoma

1 reference

based on heuristic

inferred from title

cancer cell line

1 reference

based on heuristic

inferred from title

Thomas E. Carey

13

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20 March 2020

Thorsten Stiewe

15

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20 March 2020

author name string

Manuel Tonigold

1

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20 March 2020

Annette Rossmann

2

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20 March 2020

Marie Meinold

3

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20 March 2020

Michael Bette

4

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20 March 2020

Melanie Märken

5

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20 March 2020

Katharina Henkenius

6

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20 March 2020

Anne C Bretz

7

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20 March 2020

Gavin Giel

8

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20 March 2020

Chengzhong Cai

9

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20 March 2020

Fiona R Rodepeter

10

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20 March 2020

Vladimir Beneš

11

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20 March 2020

Reidar Grénman

12

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20 March 2020

Hermann Lage

14

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20 March 2020

Andreas Neubauer

16

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20 March 2020

Cornelia Brendel

18

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20 March 2020

Robert Mandic

19

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20 March 2020

Jochen A Werner

17

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20 March 2020

language of work or name

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publication date

10 June 2014

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20 March 2020

Journal of Cancer Research and Clinical Oncology

1 reference

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20 March 2020

140

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20 March 2020

10

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20 March 2020

1689-1704

1 reference

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20 March 2020

https://scigraph.springernature.com/pub.10.1007/s00432-014-1727-y

0 references

ABCA12 mutations and autosomal recessive congenital ichthyosis: a review of genotype/phenotype correlations and of pathogenetic concepts

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Arginine482 to threonine mutation in the breast cancer resistance protein ABCG2 inhibits rhodamine 123 transport while increasing binding

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Modulation of MDR/MRP by wild-type and mutant p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Imatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Cancer chemoresistance: the relationship between p53 and multidrug transporters

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

P-glycoprotein is not expressed in a majority of colorectal carcinomas and is not regulated by mutant p53 in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Gain of function mutations in p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Mechanisms of cancer drug resistance

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Activation of multidrug efflux transporter activity at fertilization in sea urchin embryos (Strongylocentrotus purpuratus).

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

ABC transporters, mechanisms and biology: an overview

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Overexpression of cMOAT (MRP2/ABCC2) is associated with decreased formation of platinum-DNA adducts and decreased G2-arrest in melanoma cells resistant to cisplatin

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Epidermal growth factor-induced modulation of cytokeratin expression levels influences the morphological phenotype of head and neck squamous cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Reduced cisplatin sensitivity of head and neck squamous cell carcinoma cell lines correlates with mutations affecting the COOH-terminal nuclear localization signal of p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Circumvention of the multidrug-resistance protein (MRP-1) by an antitumor drug through specific inhibition of gene transcription in breast tumor cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Homozygous mutation Arg768Trp in the ABC-transporter encoding gene MRP2/cMOAT/ABCC2 causes Dubin-Johnson syndrome in a Caucasian patient

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

RNA expression of MDR1/P-glycoprotein, DNA-topoisomerase I, and MRP2 in ovarian carcinoma patients: correlation with chemotherapeutic response

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Protection of platinum-DNA adduct formation and reversal of cisplatin resistance by anti-MRP2 hammerhead ribozymes in human cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Drug insight: aminosalicylates for the treatment of IBD.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Low molecular weight heparin ablates lung cancer cisplatin-resistance by inducing proteasome-mediated ABCG2 protein degradation

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

The drug efflux pump MRP2: regulation of expression in physiopathological situations and by endogenous and exogenous compounds

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Molecular-targeted therapies in head and neck cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Pheophorbide a is a specific probe for ABCG2 function and inhibition.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Rapid detection of ABC transporter interaction: potential utility in pharmacology.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Characterization of side populations in HNSCC: highly invasive, chemoresistant and abnormal Wnt signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

ELM1 is required for multidrug resistance in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Regulation of expression of the multidrug resistance protein MRP1 by p53 in human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

ABCC2 (MRP2, cMOAT) can be localized in the nuclear membrane of ovarian carcinomas and correlates with resistance to cisplatin and clinical outcome

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Constitutive AhR activation leads to concomitant ABCG2-mediated multidrug resistance in cisplatin-resistant esophageal carcinoma cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Interaction of Positional Isomers of Quercetin Glucuronides with the Transporter ABCC2 (cMOAT, MRP2)

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

xCT inhibition depletes CD44v-expressing tumor cells that are resistant to EGFR-targeted therapy in head and neck squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

The p53 mutation "gradient effect" and its clinical implications

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Mitochondrial ABC proteins in health and disease

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS00432-014-1727-Y

21 January 2018

Expression and function of ABCG2 in head and neck squamous cell carcinoma and cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MDR1 expression correlates with mutant p53 expression in colorectal cancer metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ABCB1 and ABCG2 in the multidrug resistance of hypopharyngeal carcinoma FaDu cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transactivation of the human multidrug resistance (MDR1) gene promoter by p53 mutants.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of metastatic head and neck cancer: chemotherapy and novel agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of stem-like cells in head and neck cancer cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The individualization of cancer therapy: the unexpected role of p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glutathione in the regulation of Cisplatin resistance in cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional suppression of multidrug resistance-associated protein (MRP) gene expression by wild-type p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/24913304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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