(Q38995606)

English

20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol suppresses UV-Induced MMP-1 expression through AMPK-mediated mTOR inhibition as a downstream of the PKA-LKB1 pathway

scientific article published on October 2014

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 September 2017

20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol suppresses UV-Induced MMP-1 expression through AMPK-mediated mTOR inhibition as a downstream of the PKA-LKB1 pathway (English)

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Europe PubMed Central

PubMed publication ID

8 September 2017

13

object named as

Ki Won Lee

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Europe PubMed Central

PubMed publication ID

8 September 2017

12

object named as

Hyong Joo Lee

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8 September 2017

10

object named as

Ann M Bode

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8 September 2017

11

object named as

Zigang Dong

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8 September 2017

6

object named as

Nam Joo Kang

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PubMed publication ID

8 September 2017

Myeong-Hun Yeom

8

object named as

Myeong-Hun Yeom

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PubMed publication ID

8 September 2017

9

object named as

Deok Kun Oh

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Europe PubMed Central

PubMed publication ID

8 September 2017

author name string

Dong Joo Shin

1

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Europe PubMed Central

PubMed publication ID

8 September 2017

Jong-Eun Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Tae-Gyu Lim

3

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Europe PubMed Central

PubMed publication ID

8 September 2017

Eun Hee Jeong

4

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Europe PubMed Central

PubMed publication ID

8 September 2017

Gaeun Park

5

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8 September 2017

Jun-Seong Park

7

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PubMed publication ID

8 September 2017

language of work or name

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publication date

1 October 2014

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8 September 2017

Journal of Cellular Biochemistry

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8 September 2017

115

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PubMed publication ID

8 September 2017

10

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PubMed publication ID

8 September 2017

1702-1711

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Europe PubMed Central

PubMed publication ID

8 September 2017

Proteolytic remodeling of extracellular matrix

1 reference

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21 January 2018

Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-1 (MMP-3) protein levels in huma

1 reference

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21 January 2018

Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events

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21 January 2018

AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytes

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Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities

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Effect of compound K, a metabolite of ginseng saponin, combined with gamma-ray radiation in human lung cancer cells in vitro and in vivo

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Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: a crucial role of AMPK and mTOR pathways.

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Proapoptotic ginsenosides compound K and Rh enhance Fas-induced cell death of human astrocytoma cells through distinct apoptotic signaling pathways.

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Ginsenosides chemistry, biosynthesis, analysis, and potential health effects

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AMPKalpha1 regulates the antioxidant status of vascular endothelial cells

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Activation of rat liver cytosolic 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase by adenosine 5'-monophosphate.

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21 January 2018

Molecular basis of sun-induced premature skin ageing and retinoid antagonism.

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Defining the role of mTOR in cancer

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Targeting AMPK: a new therapeutic opportunity in breast cancer

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Compound K enhances insulin secretion with beneficial metabolic effects in db/db mice

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The AMP-activated protein kinase pathway--new players upstream and downstream.

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Regulation of AMP-activated protein kinase activity by G-protein coupled receptors: potential utility in treatment of diabetes and heart disease

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Selenium regulates cyclooxygenase-2 and extracellular signal-regulated kinase signaling pathways by activating AMP-activated protein kinase in colon cancer cells.

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Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin

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21 January 2018

20-O-β-d-glucopyranosyl-20(S)-protopanaxadiol, a metabolite of ginseng, inhibits colon cancer growth by targeting TRPC channel-mediated calcium influx.

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21 January 2018

LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism

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21 January 2018

Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin

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21 January 2018

Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation--the key step of inflammation.

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21 January 2018

Carnosol, a dietary diterpene, displays growth inhibitory effects in human prostate cancer PC3 cells leading to G2-phase cell cycle arrest and targets the 5'-AMP-activated protein kinase (AMPK) pathway

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21 January 2018

Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf.

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21 January 2018

Matrix metalloproteinases in skin

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AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

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21 January 2018

G1 phase arrest of the cell cycle by a ginseng metabolite, compound K, in U937 human monocytic leukamia cells.

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21 January 2018

Effects of red ginseng extract on UVB irradiation-induced skin aging in hairless mice.

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21 January 2018

Effects of ginseng saponins isolated from red ginseng on ultraviolet B-induced skin aging in hairless mice.

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21 January 2018

A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells

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21 January 2018

Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells

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21 January 2018

Compound K, intestinal metabolite of ginsenoside, attenuates hepatic lipid accumulation via AMPK activation in human hepatoma cells

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21 January 2018

Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine

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21 January 2018

AMP kinase/cyclooxygenase-2 pathway regulates proliferation and apoptosis of cancer cells treated with quercetin

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21 January 2018

The role of TRPV1 channel in aged human skin

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Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling

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21 January 2018

Hypoglycemic effect of protopanaxadiol-type ginsenosides and compound K on Type 2 diabetes mice induced by high-fat diet combining with streptozotocin via suppression of hepatic gluconeogenesis.

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21 January 2018

Cytokine regulation of metalloproteinase gene expression

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Akt-dependent and -independent mechanisms of mTOR regulation in cancer

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The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

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Fucoidan inhibits UVB-induced MMP-1 expression in human skin fibroblasts

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21 January 2018

Evidence that AMP triggers phosphorylation as well as direct allosteric activation of rat liver AMP-activated protein kinase. A sensitive mechanism to protect the cell against ATP depletion

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21 January 2018

AMP-activated protein kinase inhibits angiotensin II-stimulated vascular smooth muscle cell proliferation

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Structure and function of AMP-activated protein kinase.

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Ultraviolet B-induced matrix metalloproteinase-1 and -3 secretions are mediated via PTEN/Akt pathway in human dermal fibroblasts

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Cyclic AMP suppresses matrix metalloproteinase-1 expression through inhibition of MAPK and GSK-3beta

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AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway

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Growing roles for the mTOR pathway

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Reactive oxygen species are produced at low glucose and contribute to the activation of AMPK in insulin-secreting cells

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The effect of 4-hydroxypanduratin A on the mitogen-activated protein kinase-dependent activation of matrix metalloproteinase-1 expression in human skin fibroblasts

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Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

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UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes

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21 January 2018

Identifiers

10.1002/JCB.24833

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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