(Q39012184)

English

The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function.

scientific article published on 19 June 2014

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24664237%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

retracted paper

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Retraction Watch

29 December 2023

https://doi.org/10.1186/s10020-020-00265-0

http://retractionwatch.com/?s=Daniel+J+Antoine

The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function (English)

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12 March 2020

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12 March 2020

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12 March 2020

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Ravikumar A Sitapara

1

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12 March 2020

Daniel J Antoine

2

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12 March 2020

Charles R Ashby

5

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12 March 2020

Samir Gorasiya

6

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12 March 2020

Huan Yang

7

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12 March 2020

Michelle Zur

8

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12 March 2020

Lin L Mantell

9

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12 March 2020

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19 June 2014

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12 March 2020

Molecular Medicine

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12 March 2020

20

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12 March 2020

238-247

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12 March 2020

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Creative Commons Attribution 4.0 International

1 January 2014

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11 June 2022

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Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury

1 reference

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1 reference

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1 reference

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Lipopolysaccharide upregulates α7 acetylcholine receptors: stimulation with GTS-21 mitigates growth arrest of macrophages and improves survival in burned mice

1 reference

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1 reference

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Potential role of high-mobility group box 1 in cystic fibrosis airway disease.

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1 reference

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1 reference

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Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation

1 reference

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High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

1 reference

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LPS induces HMGB1 relocation and release by activating the NF-κB-CBP signal transduction pathway in the murine macrophage-like cell line RAW264.7.

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Guidelines for preventing health-care--associated pneumonia, 2003: recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee.

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24664237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2119/MOLMED.2013.00086

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24664237%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.2119/molmed.2013.00086

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24664237%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24664237%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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