(Q39012308)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

PKA signaling drives mammary tumorigenesis through Src (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author

Alexander G Beristain

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Purna A Joshi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Gilbert G Privé

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Rama Khokha

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

S D Molyneux

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

N C Pomroy

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

M A Di Grappa

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

M C Chang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

L S Kirschner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

M A Pujana

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

24 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

1160-1173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2014.41

12 March 2020

exact match

0 references

cites work

Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Phosphorylation of estrogen receptor alpha, serine residue 305 enhances activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Regulatory subunits of PKA and breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Minireview: PRKAR1A: normal and abnormal functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the carney complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

The essential role of RI alpha in the maintenance of regulated PKA activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Is expression or activation of Src kinase associated with cancer-specific survival in ER-, PR- and HER2-negative breast cancer patients?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

A pathway-based classification of human breast cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Engineering A-kinase anchoring protein (AKAP)-selective regulatory subunits of protein kinase A (PKA) through structure-based phage selection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells. Evidence of a BRCA1 and p300 exchange

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

The rapamycin-sensitive phosphoproteome reveals that TOR controls protein kinase A toward some but not all substrates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Comprehensive molecular portraits of human breast tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

A gene-expression signature as a predictor of survival in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Ductal adenoma of the breast with tubular features. A probable component of the complex of myxomas, spotty pigmentation, endocrine overactivity, and schwannomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Progesterone induces adult mammary stem cell expansion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Supervised risk predictor of breast cancer based on intrinsic subtypes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Significance analysis of microarrays applied to the ionizing radiation response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.41

31 March 2020

Identifiers

DOI

10.1038/ONC.2014.41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24662820%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference